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Relationship between sex pheromone elicited behaviour and response of single olfactory receptor neurones in a wind tunnel

Responses from pheromone-specific receptor neurones in male Agrotis segetum (Denis & Schiffermuller) (Lepidoptera: Noctuidae) were recorded in a laboratory wind tunnel. Stimuli were: (1) rubber septum dispensers loaded with single components or a four-component pheromone blend, (2) excised glands from female A. segetum, (3) constrained A. segetum females with extruded glands. Dose-response cur

Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

Microglia are the immune cells of the brain. Here we show a massive infiltration of highly ramified and elongated microglia within the core of amyloid plaques in transgenic mouse models of Alzheimer's disease (AD). Many of these cells originate from the bone marrow, and the beta-amyloid-40 and -42 isoforms are able to trigger this chemoattraction. These newly recruited cells also exhibit a specifi

Chilled ceiling displacement ventilation design charts correlations to employ in optimized system operation for feasible load ranges

This paper expands Ghaddar et al. [N. Ghaddar, K. Ghali, R. Saadeh, A. Keblawi, Design charts for combined chilled ceiling displacement ventilation system (1438-RP), ASHRAE Transactions, 143 (2) (2008) 574-587] design charts of combined chilled ceiling (CC) displacement ventilation (DV) system to operating sensible load ranges from 40 W/m(2) to 100 W/m(2). It develops a global correlation of syste

Reduced anti-TNFalpha autoantibody levels coincide with flare in systemic lupus erythematosus

Deviating cytokine patterns, as a consequence of aberrant immunoregulation, is implicated to be of aetiopathogenetic importance in systemic lupus erythematosus (SLE). To evaluate the possibility of anti-cytokine autoantibody-mediated cytokine regulation/dysregulation, IgG class autoantibodies against cytokines (IL-1beta, IL-6, IL-10, TNFalpha and TGFbeta(1)) were analysed by enzyme-linked immunoso

Patients perceptions of information about risks at cardiac surgery

Objective: The aim was to describe the patients' own experiences of risk information in connection with cardiac surgery and it's outcome. Methods: Questionnaires were answered prior to and 8 weeks after cardiac surgery. Data were analysed using qualitative content analysis. Patients in the intervention group (n = 55) received standard information and a newly written extended information brochure a

Estimation of in vivo pulmonary microvascular and interstitial geometry using digital image analysis

OBJECTIVE: To determine microvascular diameter and perivascular interstitium thickness at the lung surface in the in situ, in vivo lung. METHODS: Microscopic images of the lung surface collected through a "pleural window" by a videocamera were digitized with a monochrome frame grabber (512 x 512 pixels, 8 bits per pixels) to be computer analyzed by image processing techniques. RESULTS: We found th

Reed warbler orientation: initiation of nocturnal migratory flights in relation to visibility of celestial cues at dusk

We used radiotelemetry to investigate the time of migratory flight initiation relative to available celestial orientation cues and departure direction of a nocturnal passerine migrant, the reed warbler, Acrocephalus scirpaceus, during autumn migration. The study was carried out at Falsterbo, a coastal site in southwest Sweden. The warblers initiated migration from times well after local sunset and

The emotional climate of care-giving in home-care services

The emotional aspects of the care-giving relationship in home-care services are studied, starting from the home-care recipients' and the home-care workers' perception of the emotional climate. Their experiences of the care-giving relationship and the influence from different aspects of the care-giving situation and social processes in the work organisation are explored. Two hundred and twenty-two

Echoes of Pearl in Arda's Landscape

The world of Arda and the many stories set therein carry within them echoes of earlier tales, and even though it would be terribly reductive to discuss Tolkien’s work only in terms of its sources, knowledge of where the echoes come from contribute to our understanding and, perhaps more importantly, enjoyment of his world and stories. This is illustrated as much by the numerous university courses t

Seasonal and inter-annual photosynthetic response of representative C-4 species to soil water content and leaf nitrogen concentration across a tropical seasonal floodplain

We examined the seasonal and inter-annual variation of leaf-level photosynthetic characteristics of three C-4 perennial species, Cyperus articulatus, Panicum repens and Imperata cylindrica, and their response to environmental variables, to determine comparative physiological responses of plants representing particular microhabitats within a seasonal tropical floodplain in the Okavango River Delta,

Extended analysis of the TiI spectrum: 3d-4f, 4d-4f and 4f-5g transitions

Titanium spectra recorded in the infrared wavelength region with a Fourier Transform Spectrometer have been analysed, and 572 lines have been identified as transitions of the types 3d-4f, 4d-4f and 4-5g. 11 lines in the UV region around 2400 angstrom have been identified as belonging to the 3d(3)4s a(5)F-3d(2)4s(F-4)4f transition array. 113 levels of the 3d(2)4s(F-4)4f, 3d(3)(F-4)4f and 3d(2)4s(F-

Modulation of inflammatory mediators and ppargammaand nfkappab expression by pravastatin in response to lipoproteins in human monocytes in vitro.

Statins are inhibitors of the rate-limiting step of cellular cholesterol synthesis. In vitro and in vivo studies suggest that statins have anti-inflammatory properties independent of their cholesterol-lowering effects. These observations prompted us to examine the effects of pravastatin (50 mgr; M) and native or oxidized low density lipoprotein (nLDL or oxLDL) (50 mgr; g ml(minus sign1)) on primar

Oncoretroviral gene transfer to NOD/SCID repopulating cells using three different viral envelopes

Background The aim of this study was to investigate gene transfer to human umbilical cord blood (CB) CD34(+)/CD38(low) and NOD/SCID repopulating cells using oncoretroviral vectors and to compare the transduction efficiency using three different viral envelopes. Methods CB cells were transduced on Retronectin using an MSCV-based vector with the gene for GFP (MGIN), which was packaged into three dif

Adenovirus-mediated overexpression of murine cyclic nucleotide phosphodiesterase 3B

To construct the recombinant adenovirus vector containing the cDNA for recombinant mouse cyclic nucleotide phosphodiesterase 3B (mPDE3B), the cDNA for mPDE3B was subcloned into pACCMV.pLpA. Subsequently, this recombinant plasmid, pACCMV.mPDE3B, was cotransfected with pJM17 plasmid containing the adenoviral genome into 293 human embryonic kidney cells, and the replication-deficient adenovirus AdCMV

Extracytoplasmatic processes impaired by inactivation of the trxA (thioredoxin gene) in Bacillus subtilis

The trxA gene is regarded as essential in Bacillus subtilis, but the roles of the TrxA protein in this gram-positive bacterium are largely unknown. Inactivation of trxA results in deoxyribonucleoside and cysteine or methionine auxotrophy. This phenotype is expected if the TrxA protein is important for the activity of the class Ib ribonucleotide reductase and adenosine-5'-phosphosulfate/3'-phosphoa

Challenges and opportunities for medications development in alcoholism: An international perspective on collaborations between academia and industry

This article represents the proceedings of a symposium presented at the 12th Congress of the International Society for Biomedical Research on Alcoholism held in Heidelberg/Mannheim, Germany, on September 30, 2004. The organizers and cochairs were Bankole A. Johnson, DSc, MD, PhD, and Karl Mann, MD. The presentations included the following: (1) A Perspective from Academia, by Bankole A. Johnson, DS

On the theory of low-density convolutional codes

We introduce and analyze a new statistical ensemble of lowdensity parity-check convolutional (LDC) codes. The result of the analysis are bounds, such as a lower bound for the free distance and upper bounds for the burst error probability of the LDC codes.