Global Bodies in Grey Zones departs from the current globalised market in biological material and treatments. Three different forms of medical travel are in focus: transplant travel, fertility travel and stem cell travel. The global travelling includes legally organised cross-border care, as well as completely illegal activities involving trafficking in bodies and body parts implicating a range of

Approximately half of human-induced carbon dioxide (CO2) emissions are taken up by the land and ocean, and the rest stays in the atmosphere, increasing the global concentration and acting as a major greenhouse-gas (GHG) climate-forcing element. Although GHG mitigation is now in the political arena, the exact spatial distribution of the land sink is not well known. In this paper, an estimation of m

PURPOSE: To study the survival of adult retinal grafts prepared in a physiologically optimized way.METHODS: Twenty-three rabbits received an adult full-thickness rabbit retinal transplant positioned under the host retina, using a vitrectomy technique. The transplants were prepared using a procedure based on a previously described in vitro model used for physiological experiments on the adult retin

There is a great need to identify new and better prognostic and predictive biomarkers to stratify prostate cancer patients for optimal treatment. The aims of this study were to characterize the expression profile of pre-B cell leukemia homeobox (PBX) transcription factors in prostate cancer with an emphasis on investigating whether PBX3 harbours any prognostic value. The expression profile of PBX3

The performance of a dry sampler, with an impregnated denuder in series with a glass fibre filter, using di-n-butylamine (DBA) for airborne isocyanates (200ml min-1) is investigated and compared with an impinger flask with a glass fibre filter in series (1 l min-1). An exposure chamber containing 1,6-hexamethylene diisocyanate (HDI), isophorone diisocyanate (IPDI), and 2,4- and 2,6-toluene diisocy

In this study the effect of the dispersed state of soy phosphatidylcholine on emulsification is investigated. The emulsifier is either dispersed in the aqueous phase (coarsely, as small vesicles, as large vesicles), or it is dispersed in the oil phase. Oil-in-water emulsions are prepared with the emulsifier present in the different dispersed states. High-pressure homogenization is used for the emu

Articular cartilage consists of chondrocytes and two major components, a collagen-rich framework and highly abundant proteoglycans. Most prior studies defining the zonal distribution of cartilage have extracted proteins with guanidine-HCl. However, an unextracted collagen-rich residual is left after extraction. In addition, the high abundance of anionic polysaccharide molecules extracted from cart

X-ray photoelectron emission microscopy (XPEEM) was used in combination with other microscopic and spectroscopic techniques to follow the surface development of an aluminum brazing sheet during heating. The studied aluminum alloy sheet is a composite material designed for vacuum brazing. Its surface is covered with a native aluminum oxide film. Changes in the chemical state of the alloying element

This article asks what key concerns emerge from the way responsibility is framed in United Nations summit documents on the Sustainable Development Goals (SDGs) adopted in 2015. Our conceptual framework serves to make the study of SDG responsibility more systematic by distinguishing three main senses of responsibility: cause, obligation, and accountability. The framework structures our analysis of

Effective approaches to neuropsychiatric disorders require detailed understanding of the cellular composition and circuitry of the complex mammalian brain. Here, we present a paradigm for deconstructing the diversity of neurons defined by a specific neurotransmitter using a microfluidic dynamic array to simultaneously evaluate the expression of 96 genes in single neurons. With this approach, we su

Technologies allowing for the derivation of patient-specific neurons from somatic cells are emerging as powerful in vitro tools to investigate the intrinsic cellular pathological behaviours of the diseases that affect these patients. While the use of patient-derived neurons to model Parkinson's disease (PD) has only just begun, these approaches have allowed us to begin investigating disease pathog

It has been hypothesized that neuroinflammation triggered during brain development can alter brain functions later in life. We investigated the contribution of inflammation to the alteration of normal brain circuitries in the context of neuroexcitotoxicity following neonatal ventral hippocampal lesions in rats with ibotenic acid, an NMDA glutamate receptor agonist. Excitotoxic ibotenic acid lesion

The article explores how the notion of European integration at the local level can be conceptualized and measured. Based on a process-oriented inclusive understanding of integration and using relational datasets that maps both domestic and cross-border communication ties among political representatives in four Euroregions along the borders of Hungary–Slovakia and Sweden–Norway, we begin by applyin

BACKGROUND: Guidelines recommend estimation of glomerular filtration rate (eGFR) prior to iodine contrast media (CM) examinations. It is also recommended that absolute eGFR in mL/min, not commonly used relative GFR (adjusted to body surface area; mL/min/1.73 m(2)), should be preferred when dosing and evaluating toxicity of renally excreted drugs.PURPOSE: To validate the absolute Lund-Malmö equatio

PURPOSE: The aim of this study was to assess the atherosclerotic plaques in a large asymptomatic population stratified based on age and sex.METHODS: [18F]-2-fluoro-2-deoxy-D-glucose (FDG)-PET/CT of 100 men and 100 women, divided in four age groups were examined to assess FDG-accumulating active, calcified inactive and mixed atherosclerotic plaques in eight defined vessel segments.RESULTS: There wa

Cellulose is insoluble in water but can be dissolved in strong acidic or alkaline conditions. How well dissolved cellulose is in solution and how it organizes are key questions often neglected in literature. The typical low pH required for dissolving cellulose in acidic solvents limits the use of typical characterization techniques. In this respect, Polarization Transfer Solid State NMR (PT ssNMR)