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Acute decrease of coronary flow after indomethacin delivery in newborn lambs.

Aim: To document the effects of indomethacin (IND) on coronary flow. Methods: We studied nine premature lambs during the first day of life. The gestational age varied between 132 and 134 days (term 145 days) and weight 3.1-4.7 kg. Coronary flow velocities were recorded with an intracoronary Doppler guide wire in the proximal left anterior descending coronary artery (LAD). Average peak flow velocit

A one step motion detection circuitry

A model of motion and direction detection is presented as well as results from a computer simulation of the model. The model is based on cooperative computations which allows an extremely simple architecture. Furthermore, it involves only one logical step in its computations even though Hubel and others have argued that motion detection requires at least two. This is made possible by not including

Läskulturer. Lärare, elever och litteraturläsning i grundskolans mellanår

Popular Abstract in Swedish Avhandlingen handlar om litteraturläsning och litteraturundervisning i grundskolan. Syftet är att belysa den betydelse läsning av skönlitteratur ges i skolans mellanår i början av det tjugoförsta århundradet. Forskningsfrågorna berör de mål och föreställningar om litteratur och läsning som lärare ger uttryck för och hur dessa kommer till uttryck i konkret klassrumsarbetThis dissertation explores the teaching of literature in Swedish compulsory school. The aim of the study is to elucidate different approaches to literature instruction in upper elementary school (grades 4-6, pupils aged 10-13). The research questions focus on what goals and ideas about literature and reading guide teachers and how these are carried out in pedagogical practice and classroom activit

Incidence of myocardial infarction in elderly men being treated with antihypertensive drugs: population based cohort study

OBJECTIVE: To analyse the association between use of antihypertensive treatment, diastolic blood pressure, and long term incidence of ischaemic cardiac events in elderly men. DESIGN: Population based cohort study. Baseline examination in 1982-3 and follow up for up to 10 years. SETTING: Malmo, Sweden. SUBJECTS: 484 randomly selected men born in 1914 and living in Malmo during 1982. MAIN OUTCOME ME

Verb serialization in Kammu

This paper presents the different kinds of serial verb constructions found in Kammu (a Mon-Khmer language spoken in northern Laos). Special focus is placed on how diagnostic tests (interrogative constructions, irrealis constructions and the scope of negation) can be applied to illustrate the contrast between the most prototypical serial verb constructions (e.g. directional coverbs and resultatives

Grading scale of radiographic findings in the pubic bone and symphysis in athletes.

Purpose: Radiographic abnormalities in the pubic bone and symphysis are often seen in athletes with groin pain. The aim was to create a grading scale of such radiologic changes. Material and Methods: Plain radiography of the pelvic ring including the pubic bone and the symphysis was performed in 20 male athletes, age 19-35, with long-standing uni- or bilateral groin pain. We used two control grou

Significance and metabolism of complexed and noncomplexed prostate specific antigen forms, and human glandular kallikrein 2 in clinically localized prostate cancer before and after radical prostatectomy

PURPOSE: We studied plasma concentrations and elimination rates of prostate specific antigen (PSA) complexed to alpha1-antichymotrypsin and alpha2-macroglobulin, free PSA, total PSA (free PSA plus PSA alpha1-antichymotrypsin) and human glandular kallikrein 2 before, during and after radical retropubic prostatectomy for clinically localized prostate cancer. MATERIALS AND METHODS: Plasma was collect

Regional brain-derived neurotrophic factor mRNA and protein levels following transient forebrain ischemia in the rat

Levels of BDNF mRNA and protein were measured in the rat brain using in situ hybridization and a two-site enzyme immunoassay. Under basal conditions, the highest BDNF concentration was found in the dentate gyrus (88 ng/g), while the levels in CA3 (50 ng/g), CA1 (18 ng/g) and parietal cortex (8 ng/g) were markedly lower. Following 10 min of forebrain ischemia, BDNF protein increased transiently in

Molecular genetic analysis of severe protein C deficiency

Severe protein C deficiency is a rare, early onset, venous thrombotic condition that is inherited as an autosomal recessive trait. The protein C (PROC) genes of nine unrelated individuals with severe protein C deficiency were sequenced yielding a total of 13 different lesions. Eight of these were novel, including a gross gene deletion, three missense mutations, two micro-deletions, a splicing muta

Homozygosity for the IgG2 subclass allotype G2M(n) protects against severe infection in hereditary C2 deficiency

Homozygous C2 deficiency (C2D) is the most common deficiency of the classical complement pathway in Western countries. It is mostly found in patients with autoimmune disease or susceptibility to bacterial infections and in healthy persons. We wished to assess to what extent other immunological factors might explain differences of susceptibility to infections in C2D. For this reason, 44 Swedish pat

Interpolation classes and matrix monotone functions

An interpolation function of order n is a positive function -/+ on (0, infinity) such that vertical bar vertical bar -/+ (A)(1/2) T -/+ (A)-(1/2) vertical bar vertical bar <= max(vertical bar vertical bar T vertical bar vertical bar, vertical bar A(1/2)TA(-1/2) vertical bar vertical bar) for all n x ii matrices T and A such that A is positive definite. By a theorem of Donoghue, the class C-n of in

Measuring the size of ulcers by planimetry: a useful method in the clinical setting

OBJECTIVE: The aim of this study was to compare four measurement methods. Digital planimetry was compared with mechanical planimetry, placing the film over graph paper and counting the squares (grid tracing), and multiplying the two maximal perpendicular diameters of the ulcer (diameter product). METHOD: Twenty patients with 50 chronic leg ulcers of various aetiology and sizes (20 ulcers were < or