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Background We investigate whether, in Swedish national registers, social and psychiatric outcomes for six major psychiatric and substance disorders - drug use disorder (DUD), alcohol use disorder (AUD), major depression (MD), bipolar disorder (BD), anxiety disorder (AD), and schizophrenia (SZ) - reflect the primary genetic risk for each disorder and the level of genetic heterogeneity. Methods We u

Background Access to adequate antenatal care (ANC) is crucial for improving maternal and neonatal health outcomes. Despite high national ANC coverage, Colombia still faces regional and socioeconomic disparities. This study aims to estimate geographical and intersectional inequalities in ANC coverage and evaluate the contribution of social determinants to these disparities. Methods We conducted a c

This article analyses the rapid rise of gambling addiction in Kazakhstanwithin the broader context of Central Asia’s evolving gambling economy. Drawingon ethnographic fieldwork, it shows how digital technologies, regulatory gaps, andneoliberal reforms have expanded gambling access while deepening its harms.Official statistics vastly understate the problem, while unofficial estimates suggesthundred

Introduction Sweden, as many other high-income countries, has adopted guidelines to offer induction of labour at 41+0 gestational weeks to decrease the risk for perinatal death. As more than 20% of the pregnant population reach this gestational age, and along with other contributing factors, induction rates have increased up to 30% in many countries. Both women and care providers have raised the q

The chemical structures of dissolved organic compounds in natural waters, including the degree of aromaticity, affect their physical, chemical, and biological properties and ultimately the fate of carbon in aquatic systems and during water treatment. Herein, a new fluorescence-based aromaticity index named ARIX is shown to link the composition of aquatic dissolved organic matter to its aromaticity

Combined quantum mechanics and molecular mechanics (QM/MM) calculations are a popular approach to study reaction mechanisms of enzymes. However, recently, the reproducibility of such calculations has been questioned, comparing the results of two software: NWChem and Q-Chem. Here, we continue and extend this study by including three additional software─ComQum, ORCA, and AMBER─using the same test ca

Introduction: Obesity is a chronic, progressive, and recurring disease that contributes significantly to multimorbidity across Europe. Despite the publication of numerous clinical practice guidelines (CPGs) for obesity, many chronic disease guidelines for obesity related diseases such as diabetes, MASLD, heart disease, obstructive sleep apnea do not integrate contemporary understandings of obesity

The Nordic countries have been described as generous front-runners in their development assistance, making observers suggest the existence of a ‘Nordic Model’. They have been claimed to play a leadership role in a European and global context. Recently, however, this characterisation has been challenged due to changes in Nordic policies and in the external environment. We investigate the developmenThe Nordic countries have been described as generous front-runners in their development assistance, making observers suggest the existence of a ‘Nordic Model’. They have been claimed to play a leadership role in a European and global context. Recently, however, this characterisation has been challenged due to changes in Nordic policies and in the external environment. We investigate the developmen

Perturbed secretion of insulin and other pancreatic islet hormones is the main cause of type 2 diabetes (T2D). The islets harbor five cell types that are potentially altered differently by T2D. Whole-islet transcriptomics and single-cell RNA-sequencing (scRNAseq) studies have revealed differentially expressed genes without reaching consensus. Here, we demonstrate that further insights into T2D dis

Intelligence scholars have described the contemporary availability ofOpen-Source Intelligence (OSINT) and the entrance of civil society actorsinto the field of intelligence as a “democratization of intelligence”, therebyportraying a fundamentally positive and inclusive enterprise. Assessingthe implications of the recent explosion of OSINT groups and activists fortraditional state intelligence acto

This paper examines the impact of artificial intelligence (AI)-enabled technologies on employee pay in the United Kingdom. We use matched nationally representative data from the Employers’ Digital Practices at Work Survey and an original survey of 6000 UK workers and apply machine learning techniques to uncover relationships between AI technology and employee pay across qualification and occupatio

This study explore how visitors experience "time travel" at an open-air museum, focusing on reconstructed buildings at Fredriksdal Museums and gardens in Helsingborg. Through interviews, observations and thematic coding the research identifies elements that enhance the sense of historical immersion. Using David Kolb's experiential learning theory the analysis reveal that learning occ

Syftet med min uppsats är att undersöka hur typograferna upplevde övergången i tryckteknik mellan högtryck och offsettryck. Inledningsvis beskrivs skiftet till offsettryck och de konsekvenser som följde. Undersökningen utgår från respondenternas utsagor om teknikskiftet. I min kvalitativa analys har jag använt Bosse Angelöws teori om övergångsprocesser med individen i centrum, för att försöka förs

Avhandlingen undersöker föreningar i Sverige som organiserar öppna verkstäder. Öppna verkstäder, vilka också kallas för makerspaces, är platser som möjliggör skapande. Verktyg, maskiner och kunskap är delade mellan användarna. Syftet med avhandlingen är att undersöka hur föreningar organiserar sina delade verkstäder, vilka svårigheter föreningarna möter samt vilka implikationer detta har för den bAlternative building as an interstitial mode of transformation plays a central role in the discussion of strategies for degrowth. In this debate the questions of how alternative projects can be scaled up and how degrowth politics can gain broad societal support have been identified as crucial. In this context open workshops – grassroots infrastructures for creative activities, such as repair, upcy

In cold regions, snow cover and seasonally frozen ground (SFG) exert a substantial influence on hydrological processes, yet their effects – especially at the scale of large basins – remain insufficiently understood due to limited observations and process-based analyses. To address this, we extended the widely used Grid Xinanjiang (GXAJ) hydrological model by developing two physically meaningful ye

From Seedlings to Solutions: Which Test Will Sprout Success? Type 1 diabetes (T1D) is a condition in which the body attacks its own cells that produce insulin, a necessary hormone that allows us to use energy from food. People who do not have insulin are unable to process sugar effectively, which causes major health problems. Since there is currently no cure for this condition, affected individua