PURPOSE: This review aims to provide guidance in managing glaucoma patients more effectively. It focuses on the importance of detecting progression and measuring its rate within the management of primary open-angle glaucoma today. Recent findings strongly indicate that continued monitoring of visual fields (VFs) and reassessment of target intraocular pressures (IOPs) depending on VF progression ra

Risk stratification of patients presenting with acute chest pain is crucial for immediate and long-term management. Traditional predictors are suboptimal; therefore inflammatory biomarkers are studied for clinical assessment of patients at risk. Recently, we reported the association of IgM-uria with worse cardiovascular outcome in patients with acute chest pain. In this study, in the same cohort o

Objective: To study the effects of different doses of platelet activating factor receptor antagonist WEB 2170 on animal survival, haemodynamics, reperfusion and ultrastructural changes in the ischaemic liver in rats undergoing 90-min total hepatic inflow interruption (THII). Design: Sixty-five rats were divided into five groups. All animals underwent 90-min THII. Group 1 served as controls. Group

Summary. Assessing response to treatment with bypassing agents presents a substantial challenge in the treatment of patients with haemophilia and inhibitors. Rapid and accurate identification of bleeding episodes that are non-responsive to bypassing therapy with either Factor Eight Inhibitor Bypassing Activity (FEIBA; Baxter AG) or recombinant activated factor VII (rFVIIa; NovoSeven(®), Novo Nordi

Keratoacanthoma (KA) is difficult to histologically distinguish from squamous cell carcinoma (SCC). Therefore, although KA is a benign self-resolving skin lesion, KA is commonly treated as SCC. Biomarkers to distinguish KA and SCC would thus be desirable. In search for specific markers, paraffin-embedded tissue samples from 25 SCC and 64 KA were arranged in a tissue microarray (TMA) and stained fo

The radiative lifetimes in the s and d Rydberg sequences of neutral boron were investigated by combining the methods of laser-pulse compression and frequency-up conversion. The multiconfiguration Hartree-Fock (MCHF) method was used to calculate the lifetimes. Rydberg sequences in boron showed strong irregularities in energy due to configuration interaction. The results also showed that the energy

BACKGROUND AND AIMS:: Celiac disease is associated with tissue transglutaminase autoantibodies (tTGAb) and the human leukocyte antigen (HLA)-risk alleles DQB1*02 and DQB1*0302. The aim was to estimate the proportion of undiagnosed celiac disease in children with HLA risk at 3 years of age. PATIENTS AND METHODS:: From a population-based HLA-DQ screening study of newborns born between June 2001 and

Popular Abstract in Swedish Förmågan att planera med en medveten mental simulering har ansetts vara unikt mänsklig sedan Aristoteles. När människor planerar för psykologiska eller fysiologiska driftstillstånd som de för närvarande inte upplever, tror man att de använder sig av så kallad episodisk framförhållning. Den episodiska framförhållningen är en del av det större episodiska kognitiva systemeThe ability to plan for future, not currently experienced, mental or physiological states has been regarded as unique to humans. When humans plan for such states it has been hypothesized that they make use of what has been known as episodic foresight. Episodic foresight is a part of the episodic cognitive system, which also includes episodic memory. The defining feature of this system is so-called

Popular Abstract in Swedish Olyckor i järnvägssektorn kan ge upphov till katastrofala konsekvenser. I första hand kan människors liv och hälsa drabbas, men allvarliga konsekvenser kan även uppstå för samhället i stort. Detta beror på att järnvägssystemet, liksom en rad andra infrastruktursystem är väsentliga för att vårt moderna samhälle ska fungera. Under de senaste decennierna har dessa system bIn recent decades, the Swedish railway system has faced substantial deregulations. As a result, management of risk is often carried out in settings involving multiple stakeholders having various roles, mandates, and viewpoints on risk, and where no single stakeholder has the superior authority. In order to manage risks in this type of multi-actor setting, the traditional elements of risk assessmen

For evaluation of specific antenna arrangements in wireless communication systems we need physical channel models that take into account the directional domain. Here we propose a practical approach to wireless channel modeling in, particularly, mobile communication systems, by using an assumption that the channel can be divided into separate parts or regions that can be treated and modeled individ

Ischemic stroke is a major cause of adult disability. Stroke-induced brain damage is accompanied by inflammation - activation of resident microglia and infiltration of blood-circulating monocytes. The effect of these cells on neuro-plasticity and recovery after stroke could be detrimental as well as beneficial. The future challenge is to understand the mechanisms of action of immune cells on cellu

The aim of this study was to 1) examine the occurrence and burden of side effects over time in the period after post surgical adjuvant radiotherapy in women with breast cancer and 2) explore the women's experiences of given information and need of support to handle side effects. MATERIAL AND METHOD: 171 women with breast cancer receiving post-surgical adjuvant radiotherapy completed a questionnair

Background: Knowledge of the radiographic catheter tip position after central venous cannulation is normally not required for short-term catheter use. Detection of a possible iatrogenic pneumothorax may nevertheless justify routine post-procedure chest X-ray. Our aim was to design a clinical decision rule to select patients for radiographic evaluation after central venous cannulation. Methods: A t

This contribution provides interdisciplinary analysis of expressions of austerity-policies. It is argued that expressions of austerity-policies are meaningful if and only if intended addressees’ psychological states are adequately attuned and conceptual preconditions for implementation met. Furthermore, it is argued that if addressees are suitably psychologically attuned and preconditions met, uti

Despite an observable trend in reducing the number of layers in core and metropolitan area networks, still the optimal design of multi-layer networks (like IP over WDM) remains a important issue as a means to reduce CAPEX and OPEX. In multi-layer networks, usually a connection oriented transport network (like WDM) is used to deploy a layout for optimal transport of traffic. In today's networks, th