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P2Y12 receptor inhibitors in patients with non-STelevation acute coronary syndrome in the real world : Use, patient selection, and outcomes from contemporary European registries

Aims Non-ST-elevation acute coronary syndrome (NSTE-ACS) is present in about 60-70% of patients admitted with acute coronary syndromes in clinical practice. This study provides a 'real-life' overview of NSTE-ACS patient characteristics, dual antiplatelet therapy clinical practice, and outcomes at both the time of discharge from hospital and up to 1-year post-discharge. Methods and results A total

γ 2‐MSH increases during graded exercise in healthy subjects : comparison with plasma catecholamines, neuropeptides, aldosterone and renin activity

Summary. To evaluate the possibility that the proopiomelanocortin (POMC)‐derived peptide γ2‐melanocyte stimulating hormone (γ2‐MSH) has a role in circulatory regulation in man we studied circulating levels of this peptide at three different stages of physical activity in 10 young healthy subjects. The results were compared to simultaneously measured plasma levels of catecholamines, neuropeptide Y,

Chronic pain 1-5 years after lung transplantation

Chronic bodily pain after lung transplantation has received little attention. Therefore, the aim was to provide a multidimensional assessment of self-reported chronic pain 1-5 years after lung transplantation and its relationship with self-reported psychological general well-being (PGWB) and self-efficacy. This multicenter, cross-sectional study is a part of the Swedish national study: Self-manage

Managers’ Perceptions of Older Workers and an Extended Working Life in Sweden

Raising older workers’ participation level is a key objective in many countries. It is important therefore, to deepen the knowledge regarding older workers’ work situations.The objective of the present study was to describe how managers perceived older workers, and an extended working life, in Sweden.Seven focus groups, with a total of 26 managers, were conducted; with participants coming from mun

Multiconfigurational Quantum Chemistry

The first book to aid in the understanding of multiconfigurational quantum chemistry, Multiconfigurational Quantum Chemistry demystifies a subject that has historically been considered difficult to learn. Accessible to any reader with a background in quantum mechanics and quantum chemistry, the book contains illustrative examples showing how these methods can be used in various areas of chemistry,

Epithelial–mesenchymal transition, a spectrum of states : Role in lung development, homeostasis, and disease

Epithelial–mesenchymal transition (EMT) plays key roles during lung development and many lung diseases such as chronic obstructive pulmonary disease (COPD), lung cancer, and pulmonary fibrosis. Here, integrating morphological observations with underlying molecular mechanisms, we highlight the functional role of EMT in lung development and injury repair, and discuss how it can contribute to pathoge

On the implementation of finite deformation gradient-enhanced damage models

We introduce a comprehensive framework for the efficient implementation of finite deformation gradient-regularised damage formulations in existing finite element codes. The numerical implementation is established within a thermo-mechanically fully coupled finite element formulation, where the heat equation solution capabilities are utilised for the damage regularisation. The variationally consiste

Absorption and metabolism of orally fed arachidonic acid and linoleic acid in the rat.

[3H]arachidonic [( 3H]20:4) and [14C]linoleic acid [14C]18:2) were fed to rats in Intralipid or cream. Later (30-240 min) the stomach, small intestine, plasma, and liver were analyzed for radioactivity in different lipid classes. [3H]20:4 and [14C]18:2 were emptied from the stomach and absorbed by the intestine at similar rates. The [3H]20:4:[14C]18:2 ratio of the lipids in the small intestinal wa[3H]arachidonic [( 3H]20:4) and [14C]linoleic acid [14C]18:2) were fed to rats in Intralipid or cream. Later (30-240 min) the stomach, small intestine, plasma, and liver were analyzed for radioactivity in different lipid classes. [3H]20:4 and [14C]18:2 were emptied from the stomach and absorbed by the intestine at similar rates. The [3H]20:4:[14C]18:2 ratio of the lipids in the small intestinal wa

Professional judgements in collaboration

Although intimate partner violence is far from a new problem in society, it has lately gained increased attention both by governments and by the research community. In 2007, the Swedish government issued an action plan for “combating men’s violence against women, violence and oppression in the name of honour and violence in same-sex relationships” (2007/08:39), which included a call for increased