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This paper aims to analyze whether patients should be allowed to veto research-related use of medical data collected during routine follow-ups after their withdrawal from first-in-human clinical trials. Forms of withdrawal are identified and it is argued that the right to withdraw might be limited to some of these. The paper concludes that if veto right is denied, then: the research participant sh
PurposeThe location of a logistics facility is strategic decision, impacting distribution cost, efficiency and environmental impact. The purpose of this paper is to systemize existing knowledge by a literature review. Based on the literature review we propose a framework in this area of theoretical and practical relevance.Design/methodology/approachWe have examined the peer-reviewed literature on
In the contemporary dual crisis, economic crisis policies cannot be dealt with in isolation from the rampant and acute ecological crisis – and vice versa. In this article, we challenge the hegemonic positions in purported attempts to solve the crises so far: in the economic realm, the Keynesian episode of 2008–2009 as well as austerity policies, and with regard to the ecological crisis, ecologicalIn the contemporary dual crisis, economic crisis policies cannot be dealt with in isolation from the rampant and acute ecological crisis – and vice versa. In this article, we challenge the hegemonic positions in purported attempts to solve the crises so far: in the economic realm, the Keynesian episode of 2008–2009 as well as austerity policies, and with regard to the ecological crisis, ecological
The analysis of the angle dependence of the elastic scattering of radiation from a sample is an efficient and non-invasive technique that is used in fundamental science, in medicine and in technical quality control in industry. Precise information on the shape, size, polydispersity and interactions of a colloidal sample is readily obtained provided an underlying scattering model, i.e. form and str
Measures of three-dimensional spatial wave size are proposed and expressed in terms of properly defined characteristics: the crest-height, the length, and the wave front location. Their statistical distributions are presented in explicit integral forms for the deep water seas modeled as Gaussian fields. The proposed approach allows for investigation of the effect that shape and directionality of t
The term ‘Green Energy Economy’ (GEE) received increasing policy and scientific attention following the 2008–2009 global financial crisis, leading to the implementation of numerous ‘Green Growth’ economic stimulus packages that targeted low-carbon energy technologies. These initiatives were portrayed as key elements in the transition to a green economy, in which low-carbon energy systems would pla
Identification of the basic processes responsible for an efficient heating of intense laser produced plasmas is one of the important features of high intensity laser matter interaction studies. Collisionless absorption due to the anharmonicity in the self-consistent electrostatic potential of the plasma, known as anharmonic resonance (AHR), has been proposed to be a basic mechanism but a clear exp
Estimates indicate that the global cancer burden may be ever-increasing. Gastric cancer is one of the major cancer forms. Despite its declining incidence, the high mortality of gastric cancer makes it the third most common cause of cancer-related death. Esophageal cancer is less common, but the incidence is increasing in parts of the world. Although some progress has been made in the treatment of
The zinc finger transcription factor Wilms' tumor gene 1 (WT1) acts as an oncogene in acute myeloid leukemia. A naturally occurring alternative splice event between zinc fingers three and four, removing or retaining three amino acids (+/-KTS), is believed to change the DNA binding affinity of WT1, although there are conflicting data regarding the binding affinity and motifs of the different isofor
A detailed understanding of the dynamic processes of vehicular radio channels is crucial for its realistic modeling. In this paper, we present multipath components (MPCs) tracking results from a channel sounder measurement with 1-GHz bandwidth at a carrier frequency of 5.7 GHz. We describe in detail the applied algorithms and perform a tracking performance evaluation based on artificial channels a
