Neutrophils and extracellular traps in abdominal sepsis
Abdominal sepsis is associated with changes in systemic inflammation response and coagulation homeostasis. Excessive neutrophil activation is a key regulator in both pro-inflammatory immune response and septic lung injury. Neutrophil-derived DNA may form extracellular traps in response to invading pathogens. To examine the role of neutrophil extracellular traps for septic lung injury and systemic