According to a recent conjecture in the literature, earnings have become a poorer proxy for cash flow from operations over time. We find that since 1988, when cash flow statements started to be consistently reported in Compustat, the cash effectiveness of earnings has actually increased for a large sample of U.S. manufacturing firms. This occurs despite the introduction of fair value accounting an

This paper investigates trends in the study of Modern languages or second foreign languages (SFLs) in Swedish lower secondary school between 2000 and 2018. Over the last decades, SFLs, i.e. French, German and Spanish, have been the target of several policy measures as a response to a declining interest. However, few reports on their impact have been published. We report the proportion of pupils st

A novel technique for studies of the dynamics of molecular coherences has been developed. The concept is based on prompt excitation using broadband femtosecond (fs) laser pulses, whereupon a narrowband nanosecond (ns) laser pulse probes the fast dynamics of the coherences. Detection of the spectrally dispersed coherent signal using a streak camera allows simultaneous spectrally and temporally reso

Objective: To investigate the relationship between tear menisci and corneal nerve density in patients after laser in situ keratomileusis (LASIK). Methods: Twenty-eight eyes of 14 myopic patients were enrolled. Height and area of the upper and lower tear menisci—upper tear meniscus height, upper tear meniscus area, lower tear meniscus height (LTMH), and lower tear meniscus area (LTMA)—were measured

Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1, BRCA2, PALB2, ATM, and CHEK2 are associated with breast cancer risk. FANCM, which encodes for a DNA translocase, has been proposed as a breast cancer predisposition gene, with greater effects for the ER-negative and triple-negative breast cancer (TNBC) subtypes. We te

AIMS/HYPOTHESIS: Evidence that glucose-dependent insulinotropic peptide (GIP) and/or the GIP receptor (GIPR) are involved in cardiovascular biology is emerging. We hypothesised that GIP has untoward effects on cardiovascular biology, in contrast to glucagon-like peptide 1 (GLP-1), and therefore investigated the effects of GIP and GLP-1 concentrations on cardiovascular disease (CVD) and mortality r

Recension av doktorsavhandling om uppkomsten av handböcker i konsthistoria och genomslaget av historieskrivningens kanon och uteslutningar under 1800-talet.

This article examines the literary evidence for a settlement in Phrygia named Leonton Kephalai, i.e. Lions´Heads. According to preserved literary sources, of which there are only three, Leonton Kephalai was an important military stronghold from the Achaemenid period until the end of the Roman Republic, but the settlement may have been occupied for longer. Furthermore, one literary source specifial

This article investigates the impact of economic policy uncertainty on the British interwar economy. The first type of evidence examined is qualitative. The historical record shows that contemporaries regularly reported the incidence and consequences of major uncertainty shocks. The second type of evidence analysed is quantitative. Based on a new index of economic policy uncertainty constructed fr

To provide a consistent database for all important classes of hydrocarbons considered as components of surrogate mixtures, laminar burning velocities of n-decane, p-xylene and methylcyclohexane blended with ethanol were determined using the heat flux method at atmospheric pressure and initial temperatures of 318–400 K. The results obtained at Samara University and Lund University are within overla

In a regulatory context, skin sensitization hazard and risk evaluations of manufactured products and their ingredients (e.g. cosmetics) are mandatory in several regions. Great efforts have been made within the field of 21st Century Toxicology to provide non-animal testing approaches to assess the skin allergy potential of materials (e.g. chemicals, mixtures, nanomaterials, particles). Mechanistic

Suspensions of islet cells were prepared by shaking pancreatic islets from non inbred ob/ob mice in a Ca 2+ free buffer. The cells were incubated with or without 20 mM alloxan, and subsequently with Trypan Blue. The uptake of Trypan Blue by cell nuclei was analysed by microscope photometry and by counting the frequency of cells appearing stained on visual inspection. Cells classified as stained o

The effects of thiol compounds on insulin release were studied in microdissected pancreatic islets of non-inbred ob/ob mice. In control experiments the reactivity of thiols against 6,6′-dithiodinicotinic acid and the degradation of mouse insulin were measured. At a concentration of 0.1 mM, 1-thio-D-glucose or reduced glutathione potentiated the insulin-releasing action of 10 mM D-glucose without a

Six previously pancreatectomized dogs were transplanted with ductligated, pancreatic allografts. Glucagon and insulin levels in the venous outflow from the graft and in the systemic circulation were determined during the first 60 minutes after transplantation. Two of the dogs were subjected to L-arginine stimulation 5 days after transplantation and the glucagon levels in the venous outflow from th

Suspensions of dispersed islet cells were prepared by shaking collagenaseisolated pancreatic islets of ob ob-mice in Ca2+-free buffer. The dispersed cells exhibited a glucose uptake with stereospecificity for the d isomer and concentrated Rb+ about 30-fold from a medium containing 70 μm RbCl. These results compare well with previous observations on unbroken islets and indicate that the dispersion