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Measurement of the coherent beam properties at the CoSAXS beamline

The CoSAXS beamline at the MAX IV Laboratory is a modern multi-purpose (coherent) small-Angle X-ray scattering (CoSAXS) instrument, designed to provide intense and optionally coherent illumination at the sample position, enabling coherent imaging and speckle contrast techniques. X-ray tracing simulations used to design the beamline optics have predicted a total photon flux of 1012-1013 photons s-1

NanoMAX : The hard X-ray nanoprobe beamline at the MAX IV Laboratory

NanoMAX is the first hard X-ray nanoprobe beamline at the MAX IV laboratory. It utilizes the unique properties of the world's first operational multi-bend achromat storage ring to provide an intense and coherent focused beam for experiments with several methods. In this paper we present the beamline optics design in detail, show the performance figures, and give an overview of the surrounding infr

Gamma-Ray Imaging with Spatially Continuous Intensity Statistics

Novel methods for the inference of radiation intensityfunctions defined over known surfaces are proposed, intendedfor use in surveying applications with mobile spectrometers.Previous approaches, based on the maximum likelihoodexpectation maximization (ML-EM) framework with Poissonlikelihoods, are extended to better handle spatially continuousintensity statistics using ideas from Gaussian filtering

Distributed Neural-Network-Based Cooperation Control for Teleoperation of Multiple Mobile Manipulators Under Round-Robin Protocol

This article addresses the distributed cooperative control design for a class of sampled-data teleoperation systems with multiple slave mobile manipulators grasping an object in the presence of communication bandwidth limitation and time delays. Discrete-time information transmission with time-varying delays is assumed, and the Round-Robin (RR) scheduling protocol is used to regulate the data tran

Targeted selected reaction monitoring verifies histology specific peptide signatures in epithelial ovarian cancer

Epithelial ovarian cancer (OC) is a disease with high mortality due to vague early clinical symptoms. Benign ovarian cysts are common and accurate diagnosis remains a challenge because of the molecular heterogeneity of OC. We set out to investigate whether the disease diversity seen in ovarian cyst fluids and tumor tissue could be detected in plasma. Using existing mass spectrometry (MS)-based pro

Not All Lectins Are Equally Suitable for Labeling Rodent Vasculature

The vascular system is vital for all tissues and the interest in its visualization spans many fields. A number of different plant-derived lectins are used for detection of vasculature; however, studies performing direct comparison of the labeling efficacy of different lectins and techniques are lacking. In this study, we compared the labeling efficacy of three lectins: Griffonia simplicifolia isol

Pharmacometabolomic Profiling Of The General Population: Relation Of Active Metabolite Levels To Cardiovascular Risk Factor Control And Manifest Atherosclerosis

Introduction: The use of medications in the general population has increased over time. Information on active metabolite concentrations for common drugs in the general population is limited. Recent advances in metabolomic technologies have made high-throughput profiling of many active metabolites in large epidemiological cohorts increasingly feasible.Aim: 1. Prospective assessment of the proportio

Population-based study of multisystem inflammatory syndrome associated with COVID-19 found that 36% of children had persistent symptoms

AimOur aim was to describe the outcomes of multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19.MethodsThis national, population-based, longitudinal, multicentre study used Swedish data that were prospectively collected between 1 December 2020 and 31 May 2021. All patients met the World Health Organization criteria for MIS-C. The outcomes 2 and 8 weeks after diagnosis are

Smart and sustainable? : Five tensions in the visions and practices of the smart-sustainable city in Europe and North America

Smart cities are increasingly advocated by governments and the private sector as the primary means to deliver urban sustainability. Particularly in Europe and North America, the smart city is envisioned as a place where digital technologies are deployed to ‘solve’ urban sustainability problems. Such visions have been broadly cri- tiqued in the urban studies literature for reflecting techno-utopian

Data Governance in the Sustainable Smart City

The wisdom of ‘smart’ development increasingly shapes urban sustainability in Europe and beyond. Yet, the ‘smart city’ paradigm has been critiqued for favouring technological solutions and business interests over social inclusion and urban innovation. Despite the rhetoric of ‘citizen-centred approaches’ and ‘user-generated data’, the level of stakeholder engagement and public empowerment is still

Capturing the social value of buildings : The promise of Social Return on Investment (SROI)

Existing post-occupancy research rarely considers the importance of the sociality of the building user community and its building user group dynamics. A social value agenda is proposed to promote user- centred design within the built environment, by looking beyond physical design to consider the dy- namic interactions that exist between people and their built environment within the social context

Reflections on a policy denouement : the politics of mainstreaming zero-carbon housing

We reflect on the decision to abandon the mainstreaming of zero-carbon house building in England, in the context of our paper (Walker et al. 2015) that took this long-standing policy commitment as its case study. We consider this denouement as further evidence of how the exigencies of capital accumulation resist moves towards low-carbon transition. We reflect on what it reveals about the relation

Re-conceiving building design quality : A review of building users in their social context

Considerable overlap exists between post-occupancy research evaluating building design quality and the concept of ‘social value’, popularised by its recent application to issues of the public realm. To outline this potential research agenda, the paper reviews design quality research on buildings in rela- tion to users and their social context where the term ‘social context’ refers to building user

Conditioning demand : Older people, thermal comfort and low-carbon housing

This special issue presents findings from the ‘Conditioning Demand: Older People, Diversity, and Thermal Experience’ re- search project undertaken between 2011 and 2013. The aim of the project was to address the confluence of two key future trends: Europe's ageing population and the need to reduce domestic en- ergy consumption to counter rising utility prices and the in- creasing threat of climate

Negotiating comfort in low energy housing : The politics of intermediation

Optimising the energy performance of buildings is technically and economically challenging but it also has significant social implications. Maintaining comfortable indoor conditions while reducing energy consumption involves careful design, construction, and management of the built environment and its inhabitants. In this paper, we present findings from the study of a new low energy building for o

Living labs and co-production : university campuses as platforms for sustainability science

Living labs and co-production are increasingly popular strategies for universities to address sustainability challenges and yet the links between them remain largely implicit. This paper discusses the potential of living labs to provide a holistic and iterative framework for the co-production of knowledge. The University Living Lab initiative was launched in 2012 to transform the University of Man

Towards systemic domestic retrofit : a social practices approach

The UK housing stock will play an important role in achieving the 2050 national carbon reduction targets. Upgrading the energy performance of the existing housing stock is a significant challenge because retrofit activities are shaped by a wide range of fragmented policies, programmes and actors. Existing approaches to housing retrofit focus on regulations, financial incentives and information pro

The civics of urban nature : enacting hybrid landscapes

Urban nature is typically managed through top-down, bureaucratic, and expert-driven approaches that tend to rationalize and simplify the interactions between humans and their surround- ings. In the last few decades, there has been a significant push in cultural geography and the design disciplines to develop a relational ontology of urban nature, a perspective that emphasizes the hybrid connection