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Entropy-Controlled and Enantiodivergent Lewis Acid Catalysis in Water

Developing new and useful methods in asymmetric catalysis is of continuous importance. A current challenge is to address the imperatives of green chemistry, such that processes maximize resource-efficiency and minimize the generation of waste. To this end, this article discloses the potential of alpha-amino acids in the development of entropy-controlled and enantiodivergent Lewis acid catalysis. I

Importance of boreal rivers in providing iron to marine waters.

This study reports increasing iron concentrations in rivers draining into the Baltic Sea. Given the decisive role of iron to the structure and biogeochemical function of aquatic ecosystems, this trend is likely one with far reaching consequences to the receiving system. What those consequences may be depends on the fate of the iron in estuarine mixing. We here assess the stability of riverine iron

Quantum rings for beginners II: Bosons versus fermions

The purpose of this overview paper, which can be viewed as a supplement to our previous review on quantum rings [S. Viefers et al., Physica E 21 (2004), 1-35), is to highlight the differences of boson and fermion systems in one-dimensional (1D) and quasi-one-dimensional (Q1D) quantum rings. In particular this involves comparing their many-body spectra and other properties, in various regimes and m

Search for excited electrons in ep collisions at HERA

A search for excited electrons is performed using the full e(+/-) p data sample collected by the HI experiment at HERA, corresponding to a total luminosity of 475 pb(-1). The electroweak decays of excited electrons e* -> e gamma, e* -> eZ and e* -> vW with subsequent hadronic or leptonic decays of the W and Z bosons are considered. No evidence for excited electron production is found. Mass depende

Impact of Oxygen Coadsorption on Intercalation of Cobalt under the h-BN Nanomesh.

The process of penetration of cobalt atoms through the h-BN nanomesh on Rh(111) is investigated with both spectroscopic and microscopic techniques. It is discovered that oxygen coadsorption can drastically modify the physical properties and behavior of the deposited Co clusters upon postannealing. In the absence of oxygen, Co forms small nanoparticles in the pores (bonding parts) of the h-BN nanom

Signaling and regulation of cysteinyl leukotriene receptors in intestinal epithelial cells and colon cancer

Colorectal cancer is the third most common type of cancer, and the second leading cause of cancer-related deaths in the Western world. Chronic inflammation, such as inflammatory bowel diseases (IBD), increases the risk of cancer. Cysteinyl leukotrienes are pro-inflammatory mediators that are involved in IBD. They are ligands to the G-protein coupled receptors CysLT1R and CysLT2R, of which CysLT1R

Cryogel applications in microbiology.

There is a great demand for improved technologies with regard to rapid processing of nano- and microparticles. The handling of viruses in addition to microbial and mammalian cells requires the availability of appropriate adsorbents. Recent developments in macroporous gels produced at subzero temperatures (known as cryogels) have demonstrated an efficiency for processing cell and virus suspensions,

The effect of heat processing on the functional properties of pectin contained in olive mill wastewater

The purpose of this study was to evaluate the effect of prolonged heat processing (180 min at 50-80 degrees C) on the functional and theological properties of pectin, derived from olive mill wastewater (OMW). It was shown that a low temperature blanching of OMW at 60 degrees C, activates endogenous pectin methyl esterase and promotes demethylation, despite the high concentration of phenols. Activa

Oral and Oropharyngeal Cancer - Aspects on Epidemiology and Prognostic Markers

Head and neck cancer is a heterogeneous group of tumours, although histopathologically, >95% are squamous cell carcinomas (SCC). Some tumours respond better to therapy than others. Not enough is known to predict the outcome and tailor individualised treatment. Although one of the main risk factors, smoking, has decreased over the last decades, some head and neck cancer groups show increasing incid

Life Cycle Assessment of Biofuels in Sweden

The purpose of this study is to carry out updated and developed life cycle assessments of biofuels produced and used in Sweden today. The focuses are on making the assessments as relevant and transparent as possible and to identify hot spots which have significant impacts on the environmental performance of the specific biofuel production chains. The study includes sensitivity analyses showing the

Genetics of Osteoporosis - Studies on bone size, structure and strength in the rat

Osteoporosis is characterized by decreased bone mineral density (BMD) leading to reduced bone strength and increased fracture risk. Several heritable components affect a bone’s ability to resist fracture, including size, structure and strength; therefore identification of the genes underlying several bone characteristics will help elucidate the pathogenesis of fracture risk. Dissection of the gene

The Pancreatic Tumour Microenvironment. Influence by macrophages and glucose levels on tumourigenesis.

Popular Abstract in Swedish Vad har Nobelpristagaren i medicin 2011, huvudpersonen i Dirty Dancing, en av världens främsta tenorer och grundaren av Apple gemensamt? De drabbades alla av olika typer av bukspottkörtelcancer. Bukspottkörtelcancer är en av våra värsta cancerformer. Den drabbar årligen ca 1000 personer och 5-årsöverlevnaden är lägre än 5%. Den enda chansen till bot är via kirurgi, men Pancreatic cancer is the fourth cause of cancer-related death with a 5-year survival rate less than 5%. Two of the risk factors are chronic pancreatitis and type 2 diabetes (T2D), which are believed to promote the tumour progression. Pancreatic cancer and its tumour microenvironment is characterised by a dense stroma, immune cell infiltration and poor vascularisation. This creates a favourable env

Revised transmembrane orientation of the NADH:quinone oxidoreductase subunit NuoA.

NuoA is a small membrane spanning subunit of respiratory chain NADH:quinone oxidoreductase (complex I). Unlike the other complex I core protein subunits, the NuoA protein has no known homologue in other enzyme systems. The transmembrane orientation of NuoA cannot be unambiguously predicted, due to the small size of the polypeptide and the varying distribution of charged amino acid residues in NuoA

Strategic reversal – The network as reason, means and end

This paper describes and discusses strategic reversal in a network context. Strategic reversal here refers to how a company implements a strategy and, with a lapse of time, decides to undo that strategic change. The paper discusses strategic reversal in terms of being: (i) driven by the network or changes therein; (ii) using the network to accomplish the reversal; and (iii) affecting network parti