Popular Abstract in Swedish Inflammatoriska ledsjukdomar, innefattande bl.a. ledgångsreumatism, reumatoid artrit, och ledinflammation vid psoriasis, psoriasisartrit, är vanliga. I västvärlden lider cirka 1 procent av den vuxna befolkningen av reumatoid artrit (RA) medan psoriasisartrit (PsoA) är mindre vanlig. Ett kännetecken för dessa sjukdomar är att de medför en risk att ledernas vävnader brytsThe pathogenesis of inflammatory arthritides include synovial inflammation and joint tissue destruction. Tissue destruction has traditionally been regarded a consequence of inflammation, but recent observations indicate that the processes are not always closely linked and may proceed uncoupled. The ultimate target organs for the destructive process are articular cartilage and bone. This thesis f

Popular Abstract in Swedish Tjocktarmcancer är en av de vanligaste cancerformerna i västvärlden. I Sverige drabbas årligen ca 5000 människor. Ungefär 10% av fallen går att härleda till ärftliga faktorer medan den övervägande delen orsakas av miljöfaktorer. Kända riskfaktorer är fysisk inaktivitet, fetma och rökning. Risken för cancer påverkas dock mest av den kost vi äter. Allmänt kan sägas att enSphingomyelin (SM) is present both in eucaryotic cells and the diet. Sphingomyelinase (SMase) hydrolyses SM and generates ceramide that has been implicated in the regulation of cell growth, differentiation and apoptosis. Previously a SMase with alkaline pH optimum was identified in the intestinal tract. The thesis studied the distribution pattern, the species difference and the clinical implicatio

The management of construction tolerances is a necessary and routine part of the construction activity and is normally brought to our attention only when failures are reported. In a study of tolerance management, the authors found widespread evidence of the same failures and the reasons for them. There seems to be no shortage of experience of the effects of failures in tolerances or of knowledge a

Boken handlar om Karl Knutsson, en av centralgestalterna i 1400-talets svenska historia. Han var riksföreståndare en gång och kung tre gånger, dessutom mångårig makthavare i Finland, härskare över en del av norra Polen (Putzig), herre över sjörövare på Östersjön och en förgrundsgestalt i den svenska politiska propagandans historia. I boken skildras Karl Knutssons liv från vaggan till graven. Det ä

We describe the implementation of a gated resonant tunneling diode and its application in a wavelet generator. The GaAs-based device is fabricated by embedding a metal gate directly above a double barrier heterostructure with a peak current of 120 kA/cm2. The gate is used to modulate the tunneling current via the Schottky depletion around the buried metal. We integrate the gated tunnel diodes in o

Report of a trans-european research project that has taken place over two years (1999 – 2001) involving 15 partners from 10 EU countries, one EFTA and one non-EU country, and a European federation. On the basis of empirical and conceptual work the project proposes a common framework for education and training with a duration of six years. It is intended to be used to: Assess the adequacy of existi

The article aims at discussing the relationship between history and moral/värdegrund in didactical work, with special attention to the Swedish government's Living history initiative from 1997.

In modern chemical process industry, process state transitions, or grade changes, are common operations. Frequent production changes increase the focus on efficient operator support for such procedures. The aims of a grade change may be complex, and sometimes conflicting.Fast transitions are desirable in order to minimize production loss. There may also be safety aspects that must be considered, i

In this chapter it is argued that the feminist pioneer Mary Wollstonecraft regarded moral agency as an exercise of freedom; a person who is unfree cannot perform acts that are moral in the proper sense. There are three aspects to this deprivation: first, the psychological effects of oppression; second, processes of deliberation and reasons for action, and third, the moral character of an act, such

Germanic verb second (V2) is often said to be difficult for L2ers irrespective of their L1. Recent work on Swedish/German (e.g. vulnerable C-domain (Platzack 2001), processability (Håkansson, Pienemann & Sayehli 2001)) claims that speakers of a V2-language learning another V2-language start with a non-V2 interlanguage grammar, i.e. they don’t transfer V2, but follow a universal developmental p

This paper considers a housing market with price restrictions. On such markets, the existence of a unique minimum rationing equilibrium price vector has been established for each preference profile on a general preference domain that contains almost all preference profiles. This vector can be used as a key ingredient in a direct and strategy-proof allocation mechanism. The main contribution of thi

Popular Abstract in Swedish Sjögrens syndrom är en autoimmun sjukdom, vilket betyder att immunsystemet felreagerar och angriper kroppens egen vävnad. Nittio procent av dem som får diagnosen är kvinnor, av vilka de flesta är mellan 40 och 60 år. Vid Sjögrens syndrom, som tillhör en av våra vanligaste reumatiska sjukdomar, är det framförallt tår- och spottkörtlar som angrips och blir inflammerade. DPrimary Sjögren’s syndrome (SS) is a chronic autoimmune disease of unknown etiology. The disease primarily involves lachrymal and salivary glands, leading to dryness of the eyes and mouth, but a wide spectrum of exocrine and non-exocrine disease manifestations may be seen. A characteristic property of primary SS is the production of autoantibodies directed against intracellular, often DNA/RNA-modi

Based on Brandtler (2012), this paper argues that polarity items are sensitive to evaluability, a concept that refers to the possibility of accepting or rejecting an utterance as true in a communicative exchange. The main distinction is made between evaluable and non-evaluable utterances. The evaluable category comprises any clause that asserts, presupposes or entails the truth of an affirmative o