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Selection of DNA aptamers against rat liver X receptors

Liver X receptors alpha and beta (LXRα; LXRβ) are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors. LXRs play an important role in the reverse cholesterol transport and govern the expression of many of the proteins that are indispensable for the regulation of normal cholesterol levels in the body. SELEX, an in vitro selection technology, was used on a s

Growth mechanisms for GaAs nanowires grown in CBE

We have investigated the growth of GaAs nanowires as a function of temperatures and source pressures on (I 1 1) B-oriented substrates in chemical beam epitaxy (CBE), to establish the mechanisms that govern wire growth and to optimize growth conditions. The grown nanowires were characterized with a scanning electron microscope (SEM). We found two mechanisms to be of importance for wire growth: (i)

Ett mögelsäkrare kryprum med konventionell teknik

Denna seminarieuppsats påvisar dels de avsevärda risker för mögelpåväxt som föreligger vid normala kryprum kombinerade med bjälklag i trä samt dels en enkel metod att stävja problemen nämligen medelst markisolering i kryprummet bestående av lättklinker.

On variable rate frame independent predictive speech coding: Re-engineering iLBC

The Internet Low Bit-rate Coder (iLBC) is now widely used for Voice over Internet Protocol (VoIP) applications. Unlike speech coders such as those based on Code Excited Linear Prediction (CELP), the iLBC achieves superior robustness to packet loss by avoiding inter-frame coding dependencies. While robustness to packet loss is essential, a VoIP codec should also possess the flexibility to change it

Sensor fusion as a tool to monitor dynamic dairy processes

A system for monitoring milk and fat concentration in a dynamic milk/water system by fusing information from several sensors was investigated. Standard instrumentation for food production was used, the sensors were a conductivity meter, a density meter and an optical instrument used to measure backscattered light. The system was applied to a dynamic mixing situation. Prediction error did not excee

Male gynecomastia and risk for malignant tumours--a cohort study

BACKGROUND: Men with gynecomastia may suffer from absolute or relative estrogen excess and their risk of different malignancies may be increased. We tested whether men with gynecomastia were at greater risk of developing cancer.METHODS: A cohort was formed of all the men having a histopathological diagnosis of gynecomastia at the Department of Pathology, University of Lund, following an operation

Cooking of meat and fish in Europe - results from the European Prospective Investigation into Cancer and Nutrition (EPIC)

Objectives: There is epidemiologic evidence that the consumption of fried, grilled or barbecued meat and fish that are well-done or browned may be associated with an increased cancer risk. These high-temperature cooking methods are thought to be surrogates for mutagens and carcinogens produced in meat and fish, eg heterocyclic amines or polycyclic hydrocarbons. Since data on food cooking methods a

Does the hormonal situation modify lipid effects by lifestyle factors in middle-aged women? Results from a population-based study of Swedish women: the Women's Health in the Lund Area study.

The aim of the study was to outline whether the influence by lifestyle factors on serum lipids was modified by the hormonal situation in middle-aged women. Six thousand nine hundred eight women, aged 50 to 59 years, participated in a health assessment program, including a serum lipid profile evaluation. The women were grouped according to their hormonal status into premenopausal (PM) (n = 492), po

Twelve- and 52-Week Efficacy of the Dipeptidyl Peptidase IV Inhibitor LAF237 in Metformin-Treated Patients With Type 2 Diabetes.

OBJECTIVE—To assess the 12- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 versus placebo in patients with type 2 diabetes continuing metformin treatment. RESEARCH DESIGN AND METHODS—We conducted a 12-week, randomized, double-blind, placebo-controlled trial in 107 patients with type 2 diabetes with a 40-week extension in those completing the core study and agreeing, together

Cerebral vessel laminins and IFN-gamma y define Trypanosoma brucei brucei penetration of the blood-brain barrier

Subspecies of Trypanosoma brucei cause severe brain diseases after penetration of the blood-brain barrier. We investigated whether cytokines that modulate inflammatory cell infiltration into the brain also influence T. brucei neuroinvasion. Migration of a rodent pathogenic T. brucei strain from the cerebral blood vessels into the brain parenchyma was impeded in IFN-gamma(-/-), IFN-gamma receptor(-

Infrared polarization spectroscopy of CO2 at atmospheric pressure

Polarisation spectroscopy (PS) was used to probe CO2 gas concentration in a CO2/N-2 binary mixture at atmospheric pressure and ambient temperature. The CO2 molecules were probed by a direct laser excitation to an overtone and combination vibrational state. The tuneable narrow linewidth infrared laser radiation at 2 mum was obtained by Raman shifting of the output from a single-longitudinal-mode pu