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Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson's disease with dementia and dementia with Lewy bodies compared to Alzheimer's disease.
The objective was to study whether α-synuclein oligomers are altered in the cerebrospinal fluid (CSF) of patients with dementia, including Parkinson disease with dementia (PDD), dementia with Lewy bodies (DLB), and Alzheimer disease (AD), compared with age-matched controls.
Viruses as supramolecular self-assemblies: modelling of capsid formation and genome packaging
Viruses are considered the simplest form of live. A virus is basically composed of genomic material surrounded by a protecting capsid. Today, full molecular details of many viruses are known, and several subclasses can be discerned. In this review, we present recent advances made over the past few years obtained from theoretical considerations and model simulations to improve our understanding on
Review of: C. L. Westphahl. A Discourse Analysis of the Letter to the Hebrews. The Relationship between Form and Meaning (Library of NT Studies, 297), T & T Clark Intern. London – New York. 339 pp
Westphal's thesis contains a summary of earlier structural analyses of Hebrews. Her own discourse analysis structures Hebrews into three parts 1) 1:1–4:16; 2) 4:11–7:28 and 8:1–10:25; 3) 10:19–13:25. Westphal characterizes Heb 4:11-16 and 10:19-25 as "overlapping" parts and as keys to the structure and meaning of Hebrews. The structure according to this approach is not new. A shortcoming in this t
Heavy-flavor electron-muon correlations in p plus p and d plus Au collisions at root s(NN)=200 GeV
Background: Heavy-flavor modification in relativistic p(d) + A collisions are sensitive to different kinds of strong-interaction physics ranging from modifications of the nuclear wave function to initial- and final-state energy loss. Modifications to single heavy-flavor particles and their decay leptons at midrapidity and forward rapidity are well established at the Relativistic Heavy Ion Collider
European Association of Urology Guidelines on Male Infertility: The 2012 Update
Context: New data regarding the diagnosis and treatment of male infertility have emerged and led to an update of the European Association of Urology (EAU) guidelines for Male Infertility. Objective: To review the new EAU guidelines for Male Infertility. Evidence acquisition: A comprehensive work-up of the literature obtained from Medline, the Cochrane Central Register of Systematic Reviews, and re
Imaging of Brain Prion Protein Amyloid in Patients with Gertstmann-Straussler-Scheinker Disease
Soil water and salinity distribution under different treatments of drip irrigation.
In this study, field experiments and numerical simulations for different drip irrigation treatments in a sandy loam soil were conducted to investigate soil water and salinity distribution as well as dye infiltration patterns. Three treatments, surface drip irrigation without and with plastic mulch (T1 and T2, respectively); and subsurface drip irrigation (T3), were used. In addition, daily and bi-
CONTINENT CUTANEOUS DIVERSION AM LUNDIANA - COMPLICATIONS FROM RESERVOIR AND OUTLET
Prostate cancer diagnosed after prostate-specific antigen testing of men without clinical signs of the disease: A population-based study from the National Prostate Cancer Register of Sweden
Objective. To investigate the effects of prostate-specific antigen (PSA) testing of men without clinical signs of prostate cancer on the incidence of prostate cancer in Sweden. Material and methods. Information on the cause of diagnosis, tumour characteristics and primary treatment for patients diagnosed with prostate cancer between January 1999 and December 2007 was extracted from the National Pr
Sjuttonhundratal : Nordic Yearbook for Eighteenth-Century Studies 2010
Den matematiska punkten
Erythrocyte-derived microparticles supporting activated protein C-mediated regulation of blood coagulation.
Elevated levels of erythrocyte-derived microparticles are present in the circulation in medical conditions affecting the red blood cells. Erythrocyte-derived microparticles expose phosphatidylserine thus providing a suitable surface for procoagulant reactions leading to thrombin formation via the tenase and prothrombinase complexes. Patients with elevated levels of circulating erythrocyte-derived
Long-term characterization of persistent atrial fibrillation: wave morphology, frequency, and irregularity analysis
Short-term properties of atrial fibrillation (AF) frequency, f-wave morphology, and irregularity parameters have been thoroughly studied, but not long-term properties. In the present work, f-wave morphology is characterized by principal component analysis, introducing a novel temporal parameter defined by the cumulative normalized variance of the three largest principal components . Based on 7-day
A strong comparison principle of plurisubharmonic functions with finite pluricomplex energy
We prove a strong comparison theorem in the class ${\cal E}_p(\Omega)$ of certain plurisubharmonic functions with infinite total complex Monge-Amp\`ere masses. We also obtain a convergence theorem in ${\cal E}_p(\Omega)$
Lipid metabolites as regulators of airway smooth muscle function
Compelling evidence identifies airway smooth muscle (ASM) not only as a target but also a cellular source for a diverse range of mediators underlying the processes of airway narrowing and airway hyperresponsiveness in diseases such as asthma. These include the growing family of plasma membrane phospholipid-derived polyunsaturated fatty acids broadly characterised by the prostaglandins, leukotriene
Studying reading during writing: new perspectives in research
Asymmetric Cooperation among Wireless Relays with Linear Precoding
Wireless relays extend coverage, improve spectral efficiency, and enhance reliability and rates of wireless cellular communication systems. In this work, we introduce the fundamental notion of asymmetric cooperation among cooperating relays in cellular downlinks - different relays are party to different but overlapping knowledge about the messages transmitted from the base station. We argue that a
A Study on Evaporative Resistances of Two Skins Designed for Thermal Manikin Tore under Different Environmental Conditions
A cotton skin and Gore-Tex skin were designed for thermal manikin "Tore" to simulate different sweating styles (wet cotton skin inside and Gore-Tex outside to simulate sweating style of thermal manikin "Walter", and Gore-Tex skin inside with wet cotton skin outside to simulate sweating style of thermal manikins "Newton". The evaporative resistances of two skin combinations with clothing ensembles