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Background: Treatment of brain injuries and neurodegenerative disorders is a critical challenge due to poor regenerative capabilities of the central nervous system. The current therapeutic strategies are primarily focussed on treating the symptoms than addressing the core issue of loss of neurons. Despite advances in stem cell therapies and surgical alternatives, they are not always successful due
Introduction: Prolonged intense physical activity, such as long-distance running, may lead to systemic inflammation and cause organ injury, particularly to the kidneys. This study aimed to assess the impact of trail race running on kidney and muscle injury and gut inflammation biomarkers, and the potential mitigating effects of Lactiplantibacillus plantarum 299v (Lp299v) supplementation. Methods:
Utvecklingen av de strukturella egenskaperna hos metaller är kritisk för en effektiv användning av naturtillgångar och en cirkulär ekonomi. På senaste tid har en ny klass material med imponerande strukturella egenskaper visats sig vara väldigt intressanta, nämligen harmoniskt strukturerade material. I den här rapporten analyseras en simulering av ett dragprov för att synliggöra de essentiella mekaThe improvement of the structural properties in crystalline materials is of critical importance for an efficient use of natural resources and a circular economy. It has been found that these properties can be altered through severe plastic deformation. Bimodal harmonic structured (bHS) materials is a new class of materials having specified topological arrangement of coarse- and ultra-fine grains.
I detta arbete undersöks möjligheten att införa ett webbaserat alternativ till den nuvarande Qt-baserade gränssnittsdelen i kursen VSMN20, Programutveckling för tekniska tillämpningar, vid Lunds Tekniska Högskola. Bakgrunden är en tydlig rörelse på programvarumarknaden mot webbaserade och molnbaserade lösningar, och frågan om hur man skulle kunna få in den förändringen i en kurs där studenter arbeThis study evaluates three Python-based frameworks for developing web applications for finite element analysis: Dash, Streamlit, and NiceGUI. The evaluation focused on interactivity, usability, and suitability for inclusion in a course at LTH about software development for technical applications. To compare the frameworks, the final course project was recreated in each of them while keeping the un
The International Bladder Cancer Group (IBCG) has proposed a prognostic model for intermediate risk (IR) non-muscle invasive bladder cancer (NMIBC) for clinical decision-making. We applied the IBCG IR model in a population-based Swedish setting in patients with primary IR NMIBC diagnosed 2013-2014 in BladderBaSe 2.0. Patients were stratified into low-risk (unifocal and tumour size < 3 cm) and inte
Fixed-target platforms provide convenient support for microcrystals during serial X-ray crystallography studies using synchrotron radiation. Here, we describe a simple user-friendly 3D-printed support where the crystals are sandwiched between two layers of thin X-ray-transparent membrane resulting in very low scattering background. The platform is compatible with magnetic mounting onto the standar
Rising global temperatures and compound climatic extremes outpace avian thermoregulatory capacity. Yet, heat tolerance has been studied in only 1–2% of birds, mostly from the southern subtropics. The field requires research in two main areas. First, temperature and humidity must be considered in unison, and we provide a guiding, biophysical, framework for how these factors interact across climates
Background/Objectives: Contemporary healthcare systems are characterised by rapid change, high workload, and staff shortages, creating conditions that may compromise care quality and generate turbulence in nursing. Turbulence has been discussed in nursing research. However, greater conceptual clarity is needed regarding its underlying factors and implications for nursing work. The aim of this stud
AIMS: To investigate the prevalence of diastolic dysfunction and associated risk factors in pre-diabetes and diabetes in the general population.METHODS: Diastolic function was assessed by transthoracic echocardiography in a cross-sectional sample of 3840 men and women aged 50-64 years from the Swedish CArdioPulmonary bioImage Study. Anthropometry, medical history, blood pressure, biochemistry and
Cells must recycle stalled ribosomes while preventing the accumulation of aberrant nascent chains. In bacteria, this is achieved by overlapping pathways with distinct substrates: ribosome-rescue systems act mainly on non-stop mRNAs, whereas ribosome-associated quality control (RQC) targets mid-ORF arrests. Work in Gram-positive bacteria defined an RQC mechanism that appends C-terminal degrons to s
Background & Aims Microscopic colitis (MC) is a leading cause of chronic diarrhea, particularly in older adults. Although many patients respond to budesonide, refractory and dependent cases pose major therapeutic challenges. Although the off-label use of advanced inflammatory bowel disease therapies is expanding, robust real-world data remain scarce. Methods Through the ECCO CONFER network, we
Our point of departure has been that, by using the language of solidarity, we - consciously or not - participate in the politics of it. The group of authors coming together in this volume contribute analyses of solidarity as a norm, a process, a practice, or a vocabulary creating polyperspectivity. In so doing, we let the course of our analysis be directed by the actors we investigate over a span
Waste sorting is a cognitively demanding task with high environmental stakes. To support research on the categorisation and decision processes underlying waste sorting behaviour, this paper introduces an evaluated stimulus set of 790 images of naturally occurring waste items. The images were sampled from Danish and Swedish household waste, visually standardised, and evaluated by 526 Swedish partic
This chapter draws together some thoughts and lessons from the various contributions to this book. It reflects on some persistent issues arising from the chapters. It deliberates on the complexities of understanding, and the endeavours to ensure equality, diversity and inclusion (EDI) issues are addressed in the workplace. It also examines some emerging concerns that can likely hamper the progress
The purpose of this article is to outline and introduce research in the intersection of queerness, space and spatial design – temporarily pinning down the elusive, fluid and transitional character of queerness to make this lens more broadly available to students, practitioners and researchers in the many fields interested in space and its organisation. Hence, a normative project of making a queer
A key aspect of imperialism, colonialism, and capitalism is frontier-making. Frontiers are essential for ambitions of appropriation and extraction. This paper explores the discursive practices of frontier-making in Scandinavia including the conceptualization of parts of this region as empty space and ripe for exploitation, as wild, unruly and in need of domestication. These regions have historical
Objective: Testicular torsion (TT) is a medical emergency, difficult to identify solely through clinical evaluation. This study aims to develop an assessment algorithm with a safe lower threshold for complementary ultrasound. Material and methods: Males between 1 and 30 years of age assessed for suspected TT during the years 2019 – 2023 were retrospectively included. Clinical assessments were cond
