This thesis consists of four papers, which treat the modelling of a spur gear set and a disc brake, and the interaction between the machine elements. Features of the performance are studied in relation to the initial stated assumptions. Initially, a method for analysing the influence of profile errors upon load-sharing capabilities and mesh stiffness of spur gears was proposed. The contacts betwee

Abstract in UndeterminedWe devised a measure based on predictions of a conversation partner's opinion in order to approximatecommunicative success in an unrestricted conversation with or without access to visual information.We validated this prediction-based measure against our intuitions that participants would have lowerprediction errors in conversations where the participants rated that they co

Reflektioner i text och bild kring ett tioårigt samarbetsprojekt mellan konstnärerna Inger Bergström, Elizabet Christiansson, Tarika Lennerbjörk och Maria Wahlgren. Artikeln fokuserar särskilt på konstens och forskningens hantverk utifrån utställningen Researcher in Residence på Kunstindustrimuseum 2005.

EU:s gemensamma jordbrukspolitik handlar i allt mindre utsträckning om produktion av jordbruksprodukter och allt mer om att utveckla landsbygden samt att föra pengar till jordbruket för att stödja jordbrukets inkomster. Stora pengar satsas också i projekt för att uppmuntra företagande och skapa sysselsättning på landsbygden, såväl av gemensamma EU-medel som från den svenska budgeten. Åtgärderna sa

This thesis describes an improvement of the glyoxylate ene reaction by using siamyl glyoxaylate and a development of the novel rearrangement of allyl benzyl ethers. The glyoxylate ene reaction was used as a key reaction in a 8-step synthesis of a Taxol A-ring building block. During the work with the ene reaction it was found that the ene component underwent a rearrangement to give arylbutanals in

Levosimendan, an inodilatory drag discovered using troponin C as a target protein, has a cardiac effect deriving from the calcium sensitization of contractile proteins. The aim of this study was to give further evidence that levosimendan binds to cardiac troponin C and that the binding involves amino acid residues on helix ε of the N-terminal domain of this calcium-binding protein. Nine organic mo

Importance: This follow-up study of extremely preterm (EPT) children (

Thee three-dimensional structure of calcium-loaded regulatory, i.e. N- terminal, domain (1-91) of human cardiac troponin C (cNTnC) was determined by NMR in water/trifluoroethanol (91:9 v/v) solution. The single-calcium-loaded cardiac regulatory domain is in a 'closed' conformation with comparatively little exposed hydrophobic surface. Difference distance matrices computed from the families of Ca2+

Neurochemical evidence indicates that cognitive impairment in dementia of Alzheimer type (DAT) is related to degeneration of cholinergic neurons in the brain. A pharmacological approach is treatment with a cholinesterase inhibitor such as tetrahydroaminoacridine (THA). THA treatment of 17 patients with DAT was studied with a double-blind crossover design with three types of treatment, THA + lecith