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The in vivo production of thromboxane and prostacyclin was studied by measurements of their major urinary metabolites in eight patients undergoing total hip arthroplasty. Specific methods based on gas chromatography-mass spectrometry were used to measure the urinary excretion of 2,3-dinor-TxB2 and 2,3-dinor-6-keto-PGF1 alpha. The excretion of these metabolites increased about 10-fold during the in
Preclinical studies support an anticancer effect of statin drugs, yet epidemiologic evidence remains inconsistent regarding their role in breast cancer primary prevention. Here, we report an updated analysis of the association between statin use and breast cancer incidence in the Nurses' Health Study (NHS) cohort. Postmenopausal NHS participants without a cancer history were followed from 2000 unt
Popular AbstractI början på 1990-talet drabbades Sverige av en mycket djup ekonomisk kris. Den svenska nittiotalskrisen uppfattades inte som en tillfällig konjunkturnedgång utan som symptom på grundläggande systemfel i Sveriges ekonomi. Många bedömare menade att den s.k. svenska modellen med stor välfärdsstat och höga skatter hade försämrat marknadsekonomins effektivitet och gjort att Sverige undeIn the early 1990s, Sweden was hit by a profound economic crisis. The Swedish crisis of the nineties was not perceived as a temporary recession, but rather as a fundamental and systemic fault in Swedish economy. Many commentators held that the Swedish model with a large welfare state and high taxes had impaired Sweden's economic performance. The aim of this thesis is to empirically assess the hypo
Writing the history of philosophy to some extent also implies expressing a certain philosophy of history. This article discusses a particular case of this dialectic, namely how one has related modern philosophy to pre-modern theological philosophies when writing the history of philosophy during the 20th Century. Is the emphasis put on the continuity or the interruptions between the two traditions,
Intervju med den brittiske filmregissören Duncan Jones.
The article focuses on the ways exiled Tibetan youth interact on the Internet. It is argued that the discussions and debates on the Net not only communicate a sense of unity, but that they strive to control the various expressions of Tibetan identity as well. Internet has become an important arena for diasporic communities and must be recognized for its creative potential. The core of the debates
Objective This study examines whether neighbourhood deprivation increases the risk of giving birth to a small for gestational age (SGA) infant, after accounting for individual-level maternal socioeconomic characteristics. Design An open cohort of women, aged 20-44 years, was followed from 1 January 1992 through 31 December 2004 for first singleton births. The women's residential addresses during t
