Small cell lung cancer (SCLC; accounting for approximately 13%–15% of all lung cancers) is an exceptionally lethal malignancy characterized by rapid doubling time and high propensity to metastasize. In contrast to the increasingly personalized therapies in other types of lung cancer, SCLC is still regarded as a homogeneous disease and the prognosis of SCLC patients remains poor. Recently, however,

Youth at clinical high risk (CHR) represent a unique population enriched for precursors of major psychiatric disorders. Sleep disturbances are consistently reported in CHR individuals. However, there is a dearth of studies investigating quantifiable objective measures of sleep dysfunction in CHR youth. In this study, sleep high density (hd)-EEG recordings were collected in twenty-two CHR and twent

Breast cancer (BC) risk for BRCA1 and BRCA2 mutation carriers varies by genetic and familial factors. About 50 common variants have been shown to modify BC risk for mutation carriers. All but three, were identified in general population studies. Other mutation carrier-specific susceptibility variants may exist but studies of mutation carriers have so far been underpowered. We conduct a novel case-

Background: Occupational therapists are generally positive towards use of measuring tools. However, such use may be problematic.Purpose: To illuminate hidden and adverse effects of using measuring tools in occupational therapy.Method: A Foucauldian inspired thematic analysis of the use of measuring tools in 13 reports of practice development projects in Denmark.Findings: Three themes were construcBackground.Occupational therapists are generally positive towards use of measuring tools. However, such use may be problematic.Purpose.To illuminate hidden and adverse effects of using measuring tools in occupational therapy.Method.A Foucauldian inspired thematic analysis of the use of measuring tools in 13 reports of practice development projects in Denmark.Findings.Three themes were constructed:

This paper draws on two ethnographic research projects in Japanese university sports clubs to examine the role alcohol plays in the social and cultural education of students. Over the course of a four-year membership, the university sports club is a site where members learn to negotiate drinking. This negotiation is demonstrated by the range of strategies members employ when engaging in one of the

Bloggpost för New Review of Film and Television Studies "Short Cuts"-bloggBlog post for New Review of Film and Television Studies "Short Cuts" blog.

BACKGROUND: Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress. Transient tachypnea typically appears within the first two hours of life in term and late preterm newborns. Although transient tachypnea of the newborn is usually a self-limited condition, it is associated with wheezing syndromes in late childhood. The rationale for the use of salbutamol

Correlation between different links is an essential characteristic for many of the forthcoming radio communication systems that utilize the multiple-input-multiple-output (MIMO) technology. This paper investigates the physical phenomena that cause the inter-link correlation by introducing a measure to quantify how large amount of energy propagates via similar propagation mechanisms in different li

A full-duplex relay enhances the end-to-end spectral efficiency compared to a half-duplex relay, provided that the loop-back interference at relays is managed well. In order to study the feasibility of the full-duplex relay, it is crucial to measure and model the loop-back interference channels. This paper presents a measurement campaign of these channels for outdoor-to-indoor communications. A co

Noise pollution is a growing global public health concern. Among other issues, it has been linked with sleep disturbance, hearing functionality, increased blood pressure and heart disease. Individuals are increasingly using social media to express complaints and concerns about problematic noise sources. This behavior-using social media to post noise-related concerns-might help us better identify t

Objectives: To compare the atrial fibrillatory rate (AFR) derived from a local right atrial intracardiac recording (RA-FR) and from a single-lead surface electrocardiogram (ECG) during atrial fibrillation (AF) and to evaluate the correlation with transvenous electrical cardioversion (TVEC) threshold (in Joules), number of shocks and cardioversion success rate in horses. Animals: ECGs and clinical

We compared estrogen receptor (ER), progesterone receptor (PR), human epidermal growth-factor receptor 2 (HER2), Ki67, and grade scores among the pathology departments in Sweden. We investigated how ER and HER2 positivity rates affect the distribution of endocrine and HER2-targeted treatments among oncology departments. All breast cancer patients diagnosed between 2013 and 2018 in Sweden were iden