Bacterial ribosomes stalled on faulty, often truncated, mRNAs lacking stop codons are rescued by trans-translation. It relies on an RNA molecule (tmRNA) capable of replacing the faulty mRNA with its own open reading frame (ORF). Translation of tmRNA ORF results in the tagging of faulty protein for degradation and its release from the ribosome. We used single-particle cryo-electron microscopy to vi

Abstract is not available

Hallin, A.-L., Stjernqvist, K. (2010). Adolescents born extremely preterm: behavioral outcomes and quality of life. Scandinavian Journal of Psychology. Fifty-two extremely premature born and 54 full-term controls were assessed regarding behavioral outcomes, risk-taking and self-perceived quality of life. Behavioral outcomes were assessed with the Achenbach Youth Self Report; risk-taking was estima

The purpose of the thesis is to study whether any special professional norms exist with regard to principals’ leadership of the democratic mission which is presented to the schools. The aim is to identify norms in order to be able to later analyse and understand them. Norms exist in groups of various types, and by using the term “norm” I am addressing the actions of principals, rather than their i

Aims: To establish a cardiac cell culture model for simulated ischemia and reperfusion and in this model investigate the impact of simulated ischemia and reperfusion on expression of the calcium handling proteins FKBP12 and FKBP12.6, and intracellular calcium dynamics. Methods: HL-1 cell cultures were exposed to normoxia (as control), hypoxia, simulated ischemia (HEDA) or HEDA + reactive oxygen sp

Currently, the majority of spent batteries are not recycled but become part of the household waste in many countries, especially in China which is the largest producer and consumer of batteries. This is due to many reasons, including the lack of governmental policies to encourage and facilitate battery return and recycling. In that context this research was designed to investigate the attitudes an

We present measured J/psi production rates in d + Au collisions at root s(NN) = 200 GeV over broad ranges of transverse momentum (p(T) = 0-14 GeV/c) and rapidity (-2.2 < y < 2.2). We construct the nuclear-modification factor R-dAu for these kinematics and as a function of collision centrality (related to impact parameter for the d + Au collision). We find that the modification is largest for colli

We propose a new model that accounts for the asymmetric response of volatility to positive (`good news') and negative (`bad news') shocks in economic time series – the so-called leverage effect. In the past, asymmetric powers of errors in the conditionally heteroskedastic models have been used to capture this effect. Our model is using the gamma difference representation of the generalized Laplace

The world is facing of a number of great challenges as the population is growing and living habits are getting more resource demanding. At the same time as food security has to be assured, growth in biofuel and meat production pose a risk for increasing land use conflicts and negative environmental consequences. In this report production of food, feed and biofuels are discussed from a land use pe

Net primary production (NPP) is the principal source of energy for ecosystems and, by extension, human populations that depend on them. The relationship between the supply and demand of NPP is important for the assessment of socio-ecological vulnerability. We present an analysis of the supply and demand of NPP in the Sahel using NPP estimates from the MODIS sensor and agri-environmental data from

Background The clinical distinction between Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) is sometimes difficult, particularly in mild cases. Although CSF markers such as amyloid beta 42 (A beta 42) and P-tau can distinguish between AD and normal controls, their ability to distinguish between AD and DLB is not adequate. Objective This study aims to investigate whether CSF markers, i

We present two flexible stochastic models for 2D and 3D ocean waves with potential to reproduce severe and non-homogeneous sea conditions. The first family consists of generalized Lagrange models for the movements of individual water particles. These models can generate crest-trough and front-back statistically asymmetric waves, with the same degree of asymmetry as measured ocean waves. They are s

A three-dimensional (3D) Dirac semimetal is a novel state of quantum matter which has recently attracted much attention as an apparent 3D version of graphene. In this paper, we report results on the electronic structure of the 3D Dirac semimetal Na3Bi at a surface that reveals its nontrivial ground state. Our studies reveal that the two 3D Dirac cones go through a topological change in the constan

This Letter presents a search at the LHC for s-channel single top-quark production in proton-proton collisions at a centre-of-mass energy of 8 TeV. The analyzed data set was recorded by the ATLAS detector and corresponds to an integrated luminosity of 20.3 fb(-1). Selected events contain one charged lepton, large missing transverse momentum and exactly two b-tagged jets. A multivariate event class

1. Aquatic ecosystems in Northern Europe are expected to face increases in temperature and water colour (TB) in future. While effects of these factors have been studied separately, it is unknown whether and how a combination of them might affect phenological events and trophic interactions. 2. In a mesocosm study, we combined both factors to create conditions expected to arise during the coming ce

Abstract is not available