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Fish in a barrel : Atlantic sturgeon (Acipenser oxyrinchus) from the Baltic Sea wreck of the royal Danish flagship Gribshunden (1495)

In 1495, the royal Danish ship Gribshunden sank in the Baltic Sea, near the town of Ronneby. During archaeological excavations in 2019, a wooden barrel submerged inside the shipwreck revealed the almost complete and well-preserved remains of a sturgeon fish. In this paper, we present the find in terms of species identification, estimation of number of individuals, size reconstruction and butchery

A new dawn for (oil) incumbents within the bioeconomy? Trade-offs and lessons for policy

This paper develops a more detailed understanding of when incumbent actors may become the main locomotive driving energy transitions. It also illustrates the trade-offs between policy approaches that actively seek to involve the incumbents in transitions, and policy approaches that pursue transitions without their active involvement. The paper examines state support for the bioeconomy in Sweden an

Children with oligoarticular juvenile idiopathic arthritis have skewed synovial monocyte polarization pattern with functional impairment - a distinct inflammatory pattern for oligoarticular juvenile arthritis

Background Juvenile idiopathic arthritis (JIA) is an umbrella term of inflammatory joint diseases in children. Oligoarthritis is the most common form in the Western world, representing roughly 60% of all patients. Monocytes and macrophages play an important role in adult arthritides, but their role in oligoarticular JIA is less studied. Polarization highly influences monocytes’ and macrophages’ ef

A sustainable synthetic route for biobased 6-hydroxyhexanoic acid, adipic acid and ϵ-caprolactone by integrating bio- And chemical catalysis

A green route for the production of 6-carbon polymer building blocks 6-hydroxyhexanoic acid, adipic acid and ϵ-caprolactone from 1,6-hexanediol, a hydrogenation product of biobased 5-hydroxymethylfurfural is reported. Gluconobacter oxydans oxidized 1,6-hexanediol completely to adipic acid, and selectively at pH 6-7 to 6-hydroxyhexanoic acid, which was converted to ϵ-caprolactone by catalytic cycli

RECOMIA—a cloud-based platform for artificial intelligence research in nuclear medicine and radiology

Background: Artificial intelligence (AI) is about to transform medical imaging. The Research Consortium for Medical Image Analysis (RECOMIA), a not-for-profit organisation, has developed an online platform to facilitate collaboration between medical researchers and AI researchers. The aim is to minimise the time and effort researchers need to spend on technical aspects, such as transfer, display,

Revised stratigraphic framework for the lower Anti-Atlas supergroup based on U–Pb geochronology of magmatic and detrital zircons (Zenaga and Bou Azzer-El Graara inliers, Anti-Atlas Belt, Morocco)

U–Pb geochronology of magmatic and detrital zircons (Zenaga and Bou Azzer-El Graara inliers, Anti-Atlas Belt, Morocco) and a reassessment of the published constraints suggest a revised stratigraphic framework for the lower Anti-Atlas Supergroup. Five major unconformity-bounded lithostratigraphic packages are here distinguished: the two lower units of Paleoproterozoic age are named the Tasserda-Tag

Particle characterization and toxicity in C57BL/6 mice following instillation of five different diesel exhaust particles designed to differ in physicochemical properties

BACKGROUND: Diesel exhaust is carcinogenic and exposure to diesel particles cause health effects. We investigated the toxicity of diesel exhaust particles designed to have varying physicochemical properties in order to attribute health effects to specific particle characteristics. Particles from three fuel types were compared at 13% engine intake O2 concentration: MK1 ultra low sulfur diesel (DEP1

A Brief Breathing Space : Experiences of Brief Admission by Self-Referral for Self-Harming and Suicidal Individuals with a History of Extensive Psychiatric Inpatient Care

Individuals with severe self-harm and experiences of lengthy psychiatric admissions often have complex mental health conditions and are at risk of suicide. In this qualitative study, self-harming individuals with >180 days of psychiatric admission over 12 months shared their experiences of Brief Admission (BA), a standardized crisis-management intervention encouraging self-admission and autonomy.

Towards a bridging concept for undesirable resilience in social-ecological systems

Non-technical summaryResilience is a cross-disciplinary concept that is relevant for understanding the sustainability of the social and environmental conditions in which we live. Most research normatively focuses on building or strengthening resilience, despite growing recognition of the importance of breaking the resilience of, and thus transforming, unsustainable social-ecological systems. Undes

GDNF and Parkinson's Disease : Where Next? A Summary from a Recent Workshop

The concept of repairing the brain with growth factors has been pursued for many years in a variety of neurodegenerative diseases including primarily Parkinson's disease (PD) using glial cell line-derived neurotrophic factor (GDNF). This neurotrophic factor was discovered in 1993 and shown to have selective effects on promoting survival and regeneration of certain populations of neurons including

A combined risk score enhances prediction of type 1 diabetes among susceptible children

Type 1 diabetes (T1D)-an autoimmune disease that destroys the pancreatic islets, resulting in insulin deficiency-often begins early in life when islet autoantibody appearance signals high risk1. However, clinical diabetes can follow in weeks or only after decades, and is very difficult to predict. Ketoacidosis at onset remains common2,3 and is most severe in the very young4,5, in whom it can be li

Stora skillnader i överdödlighet våren 2020 utifrån födelseland

The Swedish strategy for dealing with covid-19 has been criticized for not accounting for difficulties of conducting voluntary social distancing in settings with household overcrowding, dependence on public transport and large proportion of service sector workers. In such neighbourhoods there is typically a larger proportion of immigrants. We compared all-cause-mortality data in Sweden by country

Clean Production of Levulinic Acid from Fructose and Glucose in Salt Water by Heterogeneous Catalytic Dehydration

Levulinic acid (LA) is considered to be one of the promising organic bio-platform chemicals and intermediates for the synthesis of fuels, chemicals, and polymers. In the present study, heterogeneous catalytic dehydration of hexose sugars, fructose and glucose, using a strong cation exchange resin (hydrogen form) as an acid catalyst, was performed to produce LA in an aqueous medium. The effect of s

Convergence analysis of iterative learning control using pseudospectra

Iterative learning control (ILC) is an approach to improve the performance of a system that repeats the sameoperation. In this paper, we apply the theory of pseudospectra to transient analysis of ILC. The focus of thispaper is on frequency-domain analysis of filter-based ILC. Moreover, the effect of finite trial length on thetransient growth is discussed.

Effects of feed composition, protein denaturation and storage of milk serum protein/lactose powders on lactosylation

During whey powder production, the feed is subjected to several heat treatments which can cause lactosylation of proteins. In this study, lactosylation of whey proteins was evaluated in spray-dried powders before and after storage by varying the native protein fraction as well as the serum protein/lactose ratio in the powders. The lactosylation of native α-lactalbumin and β-lactoglobulin in the po

Liquid fiducial marker applicability in proton therapy of locally advanced lung cancer

Background and purpose We investigated the clinical applicability of a novel liquid fiducial marker (LFM) for image-guided pencil beam scanned (PBS) proton therapy (PBSPT) of locally advanced lung cancer (LALC). Materials and methods The relative proton stopping power (RSP) of the LFM was calculated and measured. Dose perturbations of the LFM and three solid markers, in a phantom, were measured. P

Many-body calculations of two-photon, two color matrix elements for attosecond delays

Interferometric measurements based on the combination of extreme ultraviolet (XUV) attosecond pulse trains with weak infrared laser fields, have been successfully used to study time-resolved and recently angle-resolved photoemission in various atomic systems. These measurements rely on quantum interference between electron wavepackets created by absorption of XUV radiation, with further absorption

Time-resolved dynamics of thiophene dication - Probing parent molecule survival times and multi-step dissociation processes of cyclic molecules by free-electron-laser experiments combined with theoretical simulations

Thiophene is a cyclic molecule that becomes unstable as a molecular dication. We followed the multi-step dissociation dynamics triggered by soft x-ray FEL pulses from SACLA, core-ionizing the S 2p orbital and creating parent dications by the Auger decay. The time-evolution was probed by optical laser pulsesthat reveal the survival lifetime of the parent dication and the build-up of fragmentation p