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Laminar burning velocities of pyrrole/air flames : Experimental and comprehensive modeling study

Adiabatic laminar burning velocities for pyrrole/air flames were experimentally determined using the heat flux method, over equivalence ratios ranging from 0.6 to 1.3, at atmospheric pressure and initial temperature of 338 K. The detailed kinetic model of the authors was extended by the reactions of pyrrole and its intermediates based on previous theoretical studies and analogies to reactions of s

Cystatin C and derived measures of renal function as risk factors for mortality and acute kidney injury in sepsis – A post-hoc analysis of the FINNAKI cohort

Purpose: To assess the association between cystatin C-derived estimates of kidney function and mortality and acute kidney injury (AKI) in sepsis. Materials and methods: Post-hoc analysis of sepsis patients in the FINNAKI-cohort (n = 802). Primary outcome was 90-day mortality. We measured plasma cystatin C and creatinine at intensive care unit (ICU) admission and estimated glomerular filtration rat

Luteolin, a Potent Anticancer Compound : From Chemistry to Cellular Interactions and Synergetic Perspectives

Increasing rates of cancer incidence and the toxicity concerns of existing chemotherapeutic agents have intensified the research to explore more alternative routes to combat tumor. Luteolin, a flavone found in numerous fruits, vegetables, and herbs, has exhibited a number of biological activities, such as anticancer and anti-inflammatory. Luteolin inhibits tumor growth by targeting cellular proces

Low-Frequency Noise in Vertical InAs/InGaAs Gate-All-Around MOSFETs at 15 K for Cryogenic Applications

Low-frequency noise (LFN), or 1/ f -noise, can be used effectively to evaluate device reliability which is a major concern in analog as well as digital circuits. In this work, we present 1/ f -noise characterization of vertical InAs/InGaAs gate-all-around (GAA) MOSFETs with a 70-nm gate length ( LG ) measured at cryogenic temperatures down to 15 K. The measurements at cryogenic temperatures reveal

Income inequality in an industrial city during the great levelling: micro level evidence from malmö, 1900–1950

This paper contributes to the debate on historical income inequality, and especially on the decrease in inequality found in industrialised countries during the first half of the twentieth century. We use new archival individual – and household-level data for taxpayers in Sweden’s third- largest city, Malmö, from 1900 to 1950. Previous research has established that Sweden had a distinctive downtur

Human CIDEC transgene improves lipid metabolism and protects against high-fat diet–induced glucose intolerance in mice

Cell death–inducing DNA fragmentation factor-like effector C (CIDEC) expression in adipose tissue positively correlates with insulin sensitivity in obese humans. Further, E186X, a single-nucleotide CIDEC variant is associated with lipodystrophy, hypertriglyceridemia, and insulin resistance. To establish the unknown mechanistic link between CIDEC and maintenance of systemic glucose homeostasis, we

Perfusion Monitoring During Oculoplastic Reconstructive Surgery : A Comprehensive Review

PURPOSE: Knowledge of how blood perfusion is affected during and after reconstructive surgery is of great importance to predict the survival of grafts and flaps. When commonly used reconstructive procedures were developed a century ago, they were based on empirical observations of clinical outcome.METHODS: This is a comprehensive literature review that summarizes the current state of knowledge reg

Single-shot coherent control of molecular rotation by fs/ns rotational coherent anti-Stokes Raman spectroscopy

We present a novel method, to our knowledge, to control the shape of the spectra using 2-beam hybrid femtosecond (fs)/nanosecond (ns) coherent anti-Stokes Raman scattering (RCARS). The method is demonstrated experimentally and theoretically by utilizing a species-selective excitation approach via a field-free molecular alignment as an illustrative example. Two non-resonant fs laser pulses with pro

Internet-based cognitive behavior therapy for eating disorders – Development and feasibility evaluation

Background: Eating disorders (ED) are severe psychiatric conditions, characterized by decreased quality of life and high mortality. However, only a minority of patients with ED seek care and very few receive treatment. Internet-delivered cognitive behavioral therapy (ICBT) has the potential to increase access to evidence-based treatments. Aims: The aims of the present study were to (1) develop and

Simulated Microgravity Modulates Focal Adhesion Gene Expression in Human Neural Stem Progenitor Cells

We analyzed the morphology and the transcriptomic changes of human neural stem progenitor cells (hNSPCs) grown on laminin in adherent culture conditions and subjected to simulated microgravity for different times in a random positioning machine apparatus. Low-cell-density cultures exposed to simulated microgravity for 24 h showed cell aggregate formation and significant modulation of several genes

Mobility and transport for elderly and disabled persons

First Published in 1991. This is Volume 13 in a series of Transportation Studies. It contains 2 parts of the proceedings of a Conference held at Stockholmsmassan, Alvsjo, Sweden, 21-24 May 1989, organized by the Swedish Board of Transport in co-operation with the Department of Traffic Planning and Engineering, Lund Institute of Technology.

Kollektivtrafikens sårbarhet i Covid-19-eran : En holistisk strategi framåt

The role of public transport in society is crucial, particularly for those who do not have access to alternative transport modes. For public transport to be able to fulfil its societal role, it should not be perceived as unsafe or unhealthy by its (potential) users. Several studies from all over the world have shown that anxiety has increased remarkably during the pandemic, and it is likely to las

The Urothelial Transcriptomic Response to Interferon Gamma : Implications for Bladder Cancer Prognosis and Immunotherapy

Interferon gamma (IFNγ) is central to the inflammatory immune response, such as that entrained by BCG immunotherapy for bladder cancer. However, immune-mediated tumour cell killing is subject to modulation by immunoinhibitory “checkpoint” receptors such as PD-L1. We investigated the effects of IFNγ on barrier-forming in vitro-differentiated normal human urothelium using mRNA-sequencing, and showed

Intensive care patients with preeclampsia – Clinical risk factors and biomarkers for oxidative stress and angiogenic imbalance as discriminators for severe disease

Background: Approximately 180 mothers are treated in Swedish Intensive Care Units (ICU) due to preeclampsia each year. Although several clinical risk factors are known, prediction of critical disease is challenging. Two scavenger proteins, hemopexin (Hpx) and alpha-1-microglobulin (A1M) have been suggested to be associated with the oxidative stress seen in preeclampsia. The ratio of two other biom

Trisotech Tutorial

En vägledning i att lära sig grunderna i att arbeta med Trisotech Enterprise Suite för att utforma arbetsflöden i BPMN med beslutspunkter som modelleras i DMN. Syftet är att utforma modeller och lösningar för strukturerat och automatiserat beslutsfattande i verksamhetsprocesser.

Shared PV Systems in Multi-Scaled Communities

In past years, Sweden has been facing a rapid growth of photovoltaic cells, and the total PV installation capacity increased from 300 kW to 1090 MW (2006–2020). The increased number of PV users was a result of active support from the Swedish government with an aim of achieving multiple sustainable goals regarding renewable energy. This project evaluates the profitability of shared PV systems in co

Seed-coating of rapeseed (Brassica napus) with the neonicotinoid clothianidin affects behaviour of red mason bees (Osmia bicornis) and pollination of strawberry flowers (Fragaria × ananassa)

Neonicotinoid insecticides applied to flowering crops can have negative impacts on bees, with implications for crop pollination. To assess if exposure to the neonicotinoid clothianidin via a treated crop (rapeseed) affected bee behaviour, pollination performance (to strawberry), and bee reproduction, we provided each of 12 outdoor cages with rapeseed (autumn-sown plants complemented with a few spr

Rate and risk factors for thromboembolism and major bleeding in adults with congenital heart disease taking vitamin K antagonist therapy

Background: The risk of adults with a congenital heart defect (ACHD) developing heart failure, stroke, arrhythmias, and the need for valve replacement is increased compared to healthy peers. Evidence for the use of novel oral anticoagulants (NOAC) in this patient group is still lacking and vitamin K antagonists (VKA) are the primary choice for patients with a mechanical valve. The present aim was

Acid suppressants use and risk of atherosclerotic cardiovascular disease in middle-aged and older adults

Background and aims: Concerns regarding adverse events associated with the use of acid suppressants have increased. However, the impact of proton pump inhibitors (PPIs) and histamine‐2 receptor antagonists (H2RAs) on the risk of atherosclerotic cardiovascular disease (ASCVD) remains unknown. This study aimed to estimate the risk of ASCVD in association with the use of PPIs and H2RAs. Methods: This