HMGCR and rosuvastatin regulates GLP-1 secretion and expression - a translational study
CONTEXT: Statin use is associated with increased risk of type 2 diabetes and mild hyperglycemia. The underlying mechanisms are not well studied and the effect of statin treatment on GLP-1 secretion or production are unknown.OBJECTIVE: To assess the effects of rosuvastatin on GLP-1 secretion and production.METHODS: We performed association studies in the Malmö Diet and Cancer study cardiovascular c
