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Modern scholarship on medieval letters has often focused on the divide between fictionality and historicity. Attempts have been made to distinguish between ‘real’ letters and those that were used as stylistic models, and discussion has focused on how to make use of these texts as historical sources. In this volume, which draws on the proceedings of the ‘Medieval Letters between Fiction and Documen

The Byzantine Panoplia Tradition and the Greek Qur’an Translation in the Latin West

Byzantium has played only a minor role, if any at all, in the Western appropriation of knowledge on Islam. One exception to this is the Panoplia dogmatike by Eustathios Zigabenos, active under and working on the commission of the Byzantine emperor Alexios I Komnenos (r. 1081-1118). The Panoplia dogmatike ('Dogmatic Armoury') was a most imperial text, designed to support the emperor's fight against

Preliminary Evidence of Efficacy and Target Engagement of Pramipexole in Anhedonic Depression

OBJECTIVE: To investigate feasibility and target engagement of high-dose, add-on pramipexole treatment in anhedonic depression.METHOD: In this open-label pilot study, we included 12 patients with unipolar or bipolar, moderate-to-severe depression and with significant anhedonia symptoms. All patients were on a stable dose of one or a combination of antidepressants and/or mood stabilizers and receiv

Plasma circulating cell-free mitochondrial DNA in social anxiety disorder

OBJECTIVE: To investigate plasma levels of circulating cell-free mitochondrial DNA (ccf-mtDNA) in patients with social anxiety disorder (SAD) and healthy controls (HC).METHODS: In this study, 88 participants (46 patients with SAD and 42 HCs) were enrolled and both ccf-mtDNA and peripheral blood mononuclear cells (PBMC) mtDNA copy number (mtDNA-cn) were measured at up to three times per individual

Role of the co-transcriptional regulators Yap/Taz in the normal and fibrotic lung epithelia

Idiopathic pulmonary fibrosis (IPF) is a fatal disease that exhibits patterns of usual interstitial pneumonia with honeycombing. IPF is characterized by damaged distal lung epithelium with excessive tissue scarring and extracellular matrix remodeling. The etiology of IPF is unknown and current therapies cannot end or reverse disease progression. Aberrant reactivation of developmental pathways is e

Who is Woman and Who is Man? : Normativity at Intersections of Gender and Sexual Orientation

Inom nuvarande könsnormer så ses kön främst som ett uttryck av biologiska könsgrupper som är binära och olika, men kompletterande. En performativ syn på kön analyserar i stället kön som något som uppstår under sociala interaktioner genom konstant repetition av handlingar som sker inom förhärskande könsdiskurser. Dessa hegemoniska könsdiskurser konstruerar kön som fundamentalt heterosexuellt. DärmeCurrent gender norms predominantly construct gender as an expression of binary sex categories that are different but complementary. A performative view of gender instead analyses gender as an emergent feature of social interactions that is created by the constant repetition of acts in relation to discourses of gender. Within these hegemonic discourses, gender is constructed as fundamentally hetero