Infusion pump-based therapies are an effective treatment option for patients with advanced Parkinson´s disease. Achieving monotherapy with infusion-based therapies could simplify the treatment regimen, provide better medication adherence, reduce adverse events and drug interactions. This review presents the literature data on the efficacy, safety, and achievability of monotherapy with all availabl

Objective: We wanted to determine if higher compliance with American College of Sports Medicine (ACSM) exercise prescription guidelines influences exercise outcomes in knee osteoarthritis (OA). Methods: We conducted a systematic review. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, and Embase up to January 4, 2024, for randomized controlled trials evaluating resistance a

Objective. Ankylosing Spondylitis Disease Activity Score based on C-reactive protein (ASDAS-CRP) is recommended over ASDAS based on erythrocyte sedimentation rate (ASDAS-ESR) to assess disease activity in axial spondyloarthritis (axSpA). Although ASDAS-CRP and ASDAS-ESR are not interchangeable, the same disease activity cut-offs are used for both. We aimed to estimate optimal ASDAS-ESR values corr

BACKGROUND: Knee osteoarthritis (OA) is a major public health issue causing chronic pain, impaired physical function, and reduced quality of life. As there is no cure, self-management of symptoms via exercise is recommended by all current international clinical guidelines. This review updates one published in 2015.OBJECTIVES: We aimed to assess the effects of land-based exercise for people with kn

This paper investigates the relationship between the experiences of mass vaccinations against two pandemic viruses: the swine flu in 2009–2010 and COVID-19 in the early 2020s. We show how distressing memories from the swine flu vaccination, which led to the rare but severe adverse effect of narcolepsy in approximately 500 children in Sweden, were triggered by the COVID-19 pandemic. The narcolepsy

Sorption of water has a profound effect on the material properties of wood. The uptake of water vapour in wood and other materials releases more heat than the condensation of vapour to liquid water. This excess energy provides insights to the interactions and energy state of the absorbed water molecules. Modification of wood by acetylation is a common way of altering the wood-water interactions; h

This paper presents a comprehensive analysis of the operation management of a multi-node community microgrid (MG), emphasizing power flow constraints and the integration of photovoltaic (PV) and battery systems. This study formulates MG operation management as a multi-objective optimal power flow problem, aiming to minimize costs (maximize profits) and emissions simultaneously. The multi-objective

This case-control study examines differences in empathetic response of patients experiencing behavioral variant frontotemporal dementia using functional magnetic resonance imaging.

Background: Beta-cell monogenic forms of diabetes have strong support for precision medicine. We systematically analyzed evidence for precision treatments for GCK-related hyperglycemia, HNF1A-, HNF4A- and HNF1B-diabetes, and mitochondrial diabetes (MD) due to m.3243 A > G variant, 6q24-transient neonatal diabetes mellitus (TND) and SLC19A2-diabetes. Methods: The search of PubMed, MEDLINE, and Emba

Concomitant fields are the unwanted transverse components that arise when spatial encoding gradients are applied in MRI. We measured the changing gradient magnetic field at multiple locations inside the scanner and examined the internal distribution and linearity of the three vector components of the field. Our results illustrate some not-so-obvious spatial characteristics of the gradient field, w

Alla människor behöver en försörjning, vilket för majoriteten innebär att de måste arbeta. Men med vad, på vilket sätt, i vilka sociala former och hur mycket människor arbetar har varierat. Varje tid och varje samhälle har sina normer och ideal om hur folk förväntas försörja sig och vad som räknas som ett riktigt arbete. Och där det finns normer finns det också normbrott.Denna antologi handlar om

We consider the generalized Thue-Morse sequences [Formula Presented] being a parameter) defined by [Formula Presented], where s2(n) is the sum of digits of the binary expansion of n. For the polynomials [Formula Presented] we have proved in [18] that the uniform norm [Formula Presented] behaves like Nγ(c)and the best exponent γ(c) is computed. In this paper, we study the pointwise behavior and giv

What is love? Is it an uncontrollable emotion? Is it, instead, socially shaped, both an emotion and a social practice? Can the bonds of care and affection between humans and non-human animals be said to be on a par with parent-child relationships between humans? Do parents owe love to their children – and do mothers and fathers, respectively, owe it to different degrees? Do subversive weddings cha

What does it take to make a customer return? René van Pelt and Ida de Wit Sandström are retail workers in the specialist jewellery trade. They have been serving their customers together for more than fifteen years. In a world where digitalisation is changing the business conditions, demands regarding distinction and profiling are increasing and consumers are becoming ever more unpredictable , show

The need for comparative studies between experimental and numerical results exists due to the long lasting necessity for verification and validation. Accordingly, background oriented schlieren (BOS) provides a unique opportunity to perform non-intrusive quantification of density varying flows by means of an inexpensive and simple setup. As the optical flow based image processing algorithms are sho