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Impact on road safety and operation of rerouting traffic in rural travel time information system

The Travel Time Information System (TTIS) is an Intelligent Traffic Control System installed in Poland. As is common, travel time is the only factor in the decision about rerouting traffic, while a route recommendation may consider multiple criteria, including road safety. The aim of the paper is to analyze the safety level of the entire road network when traffic is rerouted on paths with differen

The human–environment nexus and vegetation–rainfall sensitivity in tropical drylands

Global climate change is projected to lead to an increase in both the areal extent and degree of aridity in the world’s drylands. At the same time, the majority of drylands are located in developing countries where high population densities and rapid population growth place additional pressure on the ecosystem. Thus, drylands are particularly vulnerable to environmental changes and large-scale env

Characterization of Mechanically Pretreated Wheat Straw for Biogas Production

Biogas production from wheat straw is one strategy of converting biomass to bioenergy, but pretreatment of the lignocellulosic material is necessary in order to render the substrate biodegradable. In this study, four different mechanical pretreatments of wheat straw were investigated: roll milling, extrusion, pelletization, and hammer milling. The effects of the pretreatments on anaerobic digestio

Compex: a cubic germanium detector

The Compex detector is an electrically cooled, composite germanium detector that uses four coaxial, cubic-shaped, single-encapsulated germanium crystals. This novel detector allows for new heights in photon detection efficiency in decay spectroscopy setups using box-shaped vacuum chambers. Its spectroscopic performance and detection efficiency is evaluated by means of source measurements. Motivate

What's normal? Microbiomes in human milk and infant feces are related to each other but vary geographically : The inspire study

Background: Microbial communities in human milk and those in feces from breastfed infants vary within and across populations. However, few researchers have conducted cross-cultural comparisons between populations, and little is known about whether certain “core” taxa occur normally within or between populations and whether variation in milk microbiome is related to variation in infant fecal microb

Towards a relational paradigm in sustainability research, practice and education

Relational thinking has recently gained increasing prominence across academic disciplines in an attempt to understand complex phenomena in terms of constitutive processes and relations. Interdisciplinary fields of study, such as science and technology studies (STS), the environmental humanities, and the posthumanities, for example, have started to reformulate academic understanding of nature-cultu

Temozolomide therapy for aggressive pituitary tumours – current understanding and future perspectives

The use of temozolomide (TMZ) for the management of aggressive pituitary tumours (APT) has revolutionised clinical practice in this field with significantly improved clinical outcomes and long-term survival. Its use is now well established however a large number of patients do not respond to treatment and recurrence after cessation of TMZ is common. A number of challenges remain for clinicians suc

Driving with and without automation on the motorway–an observational study

User-related assessment of a level 3 automated driving system, providing functions such as lane- and distance-keeping, stop & go driving, lane change and overtaking, was carried out on a motorway in Germany with the aim to assess user-related issues of automated driving, i.e., behavior when driving with automation on motorways, user experiences, reactions and acceptance. Twenty-one persons dro

Nurses’ experiences of providing nonpharmacological pain management in palliative care : A qualitative study

Aim and objectives: To explore the experiences and views of nurses who provide nonpharmacological therapies for chronic pain management in palliative care. Background: Nursing expertise in palliative care is essential in providing pain relief to patients with chronic diseases. Examinations of the use of nonpharmacological therapies for chronic pain management in palliative care have revealed what

The possible origin of the common wall lizard, Podarcis muralis (Laurenti, 1768) in Ukraine

The phylogenetic relationships and possible origin of a putative non-native population of Podarcis muralis in Ukraine were assessed based on sequences of the mitochondrial gene cytochrome b. Phylogenetic analysis showed that the Ukrainian lizards belong to two distinct mitochondrial lineages (haplogroups), both occurring within the Central Balkan clade, which includes most of central and south-eas

Correlation between membrane surface properties, polymer nature and fouling in skim milk ultrafiltration

The fouling of the membranes in skim milk ultrafiltration with the nominal molecular weight cut-off (MWCO) of 100 kDa fabricated from different polymers (polysulfone (PSF), polysulfonamide (PSA), aromatic polyamide (PA), polyacrylonitrile (PAN), cellulose acetate (CA) and regenerated cellulose (RC)) was studied. The membrane structure and physical-chemical properties of the selective layer were an

Disease duration, age at diagnosis and organ damage are important factors for cardiovascular disease in SLE

OBJECTIVE: To report the incidence rate ratios (IRR) of acute myocardial infarctions (AMI) and cerebrovascular events (CVE) in incident SLE cases from a defined population. To study the risk factors for cardiovascular events in all patients with SLE at our unit.METHODS: Patients with SLE diagnosed from 1981 to 2006 were followed through to 2016. IRRs of AMI and CVE were calculated. The AMI and CVE

Characterisation of microbial communities for improved management of anaerobic digestion of food waste

Anaerobic digestion of food waste is an attractive and increasingly popular technology within waste management and energy recovery. A better understanding of the microbiology associated with anaerobic digestion of food waste will provide new insight into the operational conditions required for optimizing this process, as well as its potential for utilisation in co-digestion systems. Eighteen full-

Circular business model experimentation : Demystifying assumptions

Circular business model experiments may help firms transition towards a circular economy. Little is known about how the participants of experimentation – entrepreneurs, intrapreneurs, innovation managers – develop and test their assumptions during the experimentation process to achieve more circular outcomes. Using a design-science approach, we investigate this process and develop principles to im

Biochar increases soil microbial biomass but has variable effects on microbial diversity : A meta-analysis

Biochar has been extensively studied as a soil amendment for carbon sequestration and for improving soil quality; however, a systematic understanding of the responses of soil microbial biomass and diversity to biochar addition is lacking. Here, a meta-analysis of 999 paired data points from 194 studies shows that biochar increases microbial biomass but has variable effects on microbial diversity.

STAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population

Cancer stem cells (CSCs) are a small subpopulation of quiescent cells with the potential to differentiate into tumor cells. CSCs are involved in tumor initiation and progression and contribute to treatment failure through their intrinsic resistance to chemo- or radiotherapy, thus representing a substantial concern for cancer treatment. Prostate CSCs’ activity has been shown to be regulated by the

Diffusion tensor distribution imaging of an in vivo mouse brain at ultrahigh magnetic field by spatiotemporal encoding

Diffusion tensor distribution (DTD) imaging builds on principles from diffusion, solid-state and low-field NMR spectroscopies, to quantify the contents of heterogeneous voxels as nonparametric distributions, with tensor “size”, “shape” and orientation having direct relations to corresponding microstructural properties of biological tissues. The approach requires the acquisition of multiple images

Evaluating the outcomes of collaborative wildlife governance : The role of social-ecological system context and collaboration dynamics

The acknowledgement of uncertainty and complexity in social-ecological systems has increased the implementation of collaborative governance regimes for environmental issues. The performance of these new regimes to deliver favourable social and ecological outcomes must therefore be evaluated. We focus on the case of Swedish wildlife governance, which has a tradition of using collaborative elements.