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What drives home solar PV uptake? Subsidies, peer effects and visibility in Sweden

Solar PV capacity in Sweden has grown considerably in the last years, however and despite techno-economic potential, its share in the power mix remains rather marginal. There are growing claims about economic and non-monetary factors driving the (non-)adoption of solar PV, but quantitative evidence about potential adopters is rather limited. Our study addresses this gap and investigates subsidy ef

Neuroimaging, genetic, clinical, and demographic predictors of treatment response in patients with social anxiety disorder

Background: Correct prediction of treatment response is a central goal of precision psychiatry. Here, we tested the predictive accuracy of a variety of pre-treatment patient characteristics, including clinical, demographic, molecular genetic, and neuroimaging markers, for treatment response in patients with social anxiety disorder (SAD). Methods: Forty-seven SAD patients (mean±SD age 33.9 ± 9.4 ye

Intrinsic memory of temporal intervals in cerebellar Purkinje cells

The general consensus for learning and memory, including in the cerebellum, is that modification of synaptic strength via long-term potentiation (LTP) or long-term depression (LTD) are the primary mechanisms for the formation of memories. Recent findings suggest additional cellular mechanisms – referred to as ‘intrinsic plasticity’ – where a neuron's membrane excitability intrinsically changes. Th

Preschool attendance, schooling, and cognitive skills in East Africa

We study the effects of preschool attendance on children's schooling and cognitive skills in Kenya and Tanzania. We use a within-household estimator and data from nationally representative surveys of school-age children's literacy and numeracy skills, which include retrospective information on preschool attendance. In both countries, school entry rules are not strictly enforced, and children who a

Impact of variations in residential use of household electricity on the energy and power demand for space heating – Variations from measurements in 1000 apartments

Low energy buildings are usually characterized by a very well insulated building envelope and an efficient ventilation system that makes use of the heat in the exhaust air. Internal heat gains from residents and their use of appliances can cover the heating demand to a certain extent. The magnitude of internal heat gains that cover demand are often modelled in a simplified way and thus can be asso

Low-temperature back-end-of-line technology compatible with III-V nanowire MOSFETs

We present a low-temperature processing scheme for the integration of either lateral or vertical nanowire (NW) transistors with a multilayer back-end-of-line interconnect stack. The nanowire device temperature budget has been addressed, and materials for the interconnect fabrication have been selected accordingly. A benzocyclobutene (BCB) polymer is used as an interlayer dielectric, with interconn

A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy

Der p 2 is one of the most important allergens from the house dust mite Dermatophagoides pteronyssinus Identification of human IgE Ab binding epitopes can be used for rational design of allergens with reduced IgE reactivity for therapy. Antigenic analysis of Der p 2 was performed by site-directed mutagenesis based on the x-ray crystal structure of the allergen in complex with a Fab from the murine

Roadmap for valuing soil ecosystem services to inform multi-level decision-making in agriculture

Agricultural soils contribute to human welfare through their generation of manifold ecosystem services such as food security, water quality and climate regulation, but these are degraded by common farming practices. We have developed a roadmap for evaluating the contribution of both private- and public-good ecosystem services generated by agricultural soils to societal welfare. The approach consid

Clinical characteristics of subependymal giant cell astrocytoma in tuberous sclerosis complex

Background: This study evaluated the characteristics of subependymal giant cell astrocytoma (SEGA) in patients with tuberous sclerosis complex (TSC) entered into the TuberOus SClerosis registry to increase disease Awareness (TOSCA). Methods: The study was conducted at 170 sites across 31 countries. Data from patients of any age with a documented clinical visit for TSC in the 12 months preceding en

Kulturmiljöer i odlingslandskapet – hur kan de bevaras?

Kulturmiljöer som historiska byggnader, stenmurar, diken och alléer är värdefulla delar av vårt kulturarv. Om miljöerna ska bevaras krävs att ersättningen för skötsel av dem är så pass attraktiv att många väljer att ansluta sig. Förutom nivån på den ekonomiska ersättningen finns en rad faktorer som spelar roll för viljan att ansluta sig, och vissa av dessa kan stimuleras av så kallad nudging.Denna

Oxygen Therapy in Myocardial Infarction Patients With or Without Diabetes : A Predefined Subgroup Analysis From the DETO2X-AMI Trial

OBJECTIVE: To determine the effects of oxygen therapy in myocardial infarction (MI) patients with and without diabetes. RESEARCH DESIGN AND METHODS: In the Determination of the Role of Oxygen in Suspected Acute Myocardial Infarction (DETO2X-AMI) trial, 6,629 normoxemic patients with suspected MI were randomized to oxygen at 6 L/min for 6-12 h or ambient air. In this prespecified analysis involving

Comparison of conventional and Si-photomultiplier-based PET systems for image quality and diagnostic performance

BACKGROUND: A new generation of positron emission tomography with computed tomography (PET-CT) was recently introduced using silicon (Si) photomultiplier (PM)-based technology. Our aim was to compare the image quality and diagnostic performance of a SiPM-based PET-CT (Discovery MI; GE Healthcare, Milwaukee, WI, USA) with a time-of-flight PET-CT scanner with a conventional PM detector (Gemini TF; P

Immune effector monocyte–neutrophil cooperation induced by the primary tumor prevents metastatic progression of breast cancer

Metastatic behavior varies significantly among breast cancers. Mechanisms explaining why the majority of breast cancer patients never develop metastatic outgrowth are largely lacking but could underlie the development of novel immunotherapeutic target molecules. Here we show interplay between nonmetastatic primary breast cancer and innate immune response, acting together to control metastatic prog

Prevalence of Survival Without Major Comorbidities Among Adults Born Prematurely

Importance: Preterm birth has been associated with cardiometabolic, respiratory, and neuropsychiatric disorders in adulthood. However, the prevalence of survival without any major comorbidities is unknown. Objective: To determine the prevalence of survival without major comorbidities in adulthood among persons born preterm vs full-term. Design, Setting, and Participants: National cohort study of a

Educational inequalities in all-cause and cause-specific mortality among people with gout : a register-based matched cohort study in southern Sweden

BACKGROUND: Gout is the most common inflammatory arthritis with a rising prevalence around the globe. While educational inequalities in incidence and prevalence of gout have been reported, no previous study investigated educational inequality in mortality among people with gout. The aim of this study was to assess absolute and relative educational inequalities in all-cause and cause-specific morta