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Determination of non-steroidal anti-inflammatory drugs in sewage sludge by direct hollow fiber supported liquid membrane extraction and liquid chromatography-mass spectrometry

In this study, a three-phase hollow fiber liquid-phase microextraction (HF-LPME) method combined with liquid chromatography-mass spectrometry was developed for direct determination of four non-steroidal anti-inflammatory drugs (ketoprofen, naproxen, diclofenac and ibuprofen) in sewage sludge. The drugs were extracted from non-spiked and spiked slurry samples with different amounts of sludge into a

Fibroblasts as matrix modulating cells in asthma and COPD

Chronic lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are two lung diseases that are continuously increasing worldwide. Despite extensively research to find curative treatment, no so such therapy exists today. New hypothesis suggests that an aberrant chronic wound healing process takes place which involves both the classical inflammation and more chronic changes of

Search for direct photons in p+Pb and p+C collisions at sqrt(snn) = 17.4 GeV

Upper limits on direct photon production were determined as a function of the transverse momentum for 0.7 < pT ≤ 3.2 GeV/c with the WA98 experiment in p + C and p + Pb collisions at . The results are compared to direct photon measurements in Pb + Pb collisions at by WA98. Implications for a possible thermal direct photon contribution are discussed.

Rätt, makt och institutionell förändring : En kritisk analys av myndigheters samverkan i barnahus

Popular Abstract in Swedish Avhandlingens övergripande syfte är att kritiskt studera interorganisatoriska samverkansprocesser och sammanhängande konsekvenser, med ett särskilt fokus på rättens och maktens betydelse. Analysen av det empiriska materialet, som speglar samverkan i en kontext av barnahus på sex orter i Sverige (samverkan under ett tak kring utredningar av misstänkta brott mot barn), The overarching objective of the dissertation is to study inter-organisational collaboration processes and their associated consequences in a critical manner, with particular emphasis on the importance of law and power. The analysis of the empirical material, reflecting collaboration in the context of Barnahus on six locations in Sweden (collaboration under one roof regarding investigations of s

Commercial potato protein concentrate as a novel source for thermoformed bio-based plastic films with unusual polymerisation and tensile properties

Commercial potato protein concentrate (PPC) was investigated as a source of thermoformed bio-based plastic film. Pressing temperatures of 100 to 190 degrees C with 15 to 25% glycerol were used to form PPC films. The shape of the tensile stress-strain curve in thermoformed PPC was controlled by glycerol level and was independent of processing temperature. Tensile testing revealed that elongation at

Cost-effectiveness of infliximab versus conventional combination treatment in methotrexate-refractory early rheumatoid arthritis: 2-year results of the register-enriched randomised controlled SWEFOT trial.

OBJECTIVE: To estimate the incremental cost-effectiveness of infliximab versus conventional combination treatment over 21 months in patients with methotrexate-refractory early rheumatoid arthritis. METHODS: In this multicentre, two-arm, parallel, randomised, active-controlled, open-label trial, rheumatoid arthritis patients with

The Flow Rate of People during Train Evacuation in Rail Tunnels: Effects of Different Train Exit Configurations

An exploratory study of a train evacuation inside a tunnel was performed in order to study the effects of different train exit configurations on the flow rate of people through the exit. A total of 84 participants in the ages 18–40 years took part in the experiment, which was carried out on two separate days and involved 18 evacuation scenarios. The statistical analysis of the experiment demonstra

ICUD-EAU International Consultation on Bladder Cancer 2012: Non-Muscle-Invasive Urothelial Carcinoma of the Bladder

Context: Our aim was to present a summary of the Second International Consultation on Bladder Cancer recommendations on the diagnosis and treatment options for non-muscle-invasive urothelial cancer of the bladder (NMIBC) using an evidence-based approach. Objective: To critically review the recent data on the management of NMIBC to arrive at a general consensus. Evidence acquisition: A detailed Med

The structuring of quantitative genetic variation in a fragmented population of Briza media (Poaceae)

The structuring of quantitative genetic variation can have a significant impact on the adaptive potential and long-term viability of species in changing landscapes. The present study of the grass Briza media investigated the relationships between patterns of heritable variation in phenotypic characters and descriptors of landscape structure, land-use history and local habitat conditions in a lands

Raphidicyrtis trichosporella new to Sweden.

Rhaphidicyrtis trichosporella (Nyl.) Vain. is reported here as new to Sweden from five sites in the southernmost part of the country, two in the province of Skåne and three in Småland. All sites are deciduous woodlands of different composition, but most likely with a long ecological continuity. Two records are from scaling bark of Alnus glutinosa in Alnus swamps, two from hard and smooth bark of F

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene.

The Kruppel-like protein ZNF224 is a co-factor of the Wilms' tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in chronic myelogenous leukemia (CML) K562 cells and contributes to cytosine arabinoside-induced apoptosis, by modulating WT1-dependent transcription of apoptotic genes. Here we demonstrate that ZNF224 gene expression is down-regulated both in

Measurement of the total cross section from elastic scattering in pp collisions at root s=7 TeV with the ATLAS detector

A measurement of the total pp cross section at the LHC at root s = 7 TeV is presented. In a special run with high-beta* beam optics, an integrated luminosity of 80 mu b(-1) was accumulated in order to measure the differential elastic cross section as a function of the Mandelstam momentum transfer variable t. The measurement is performed with the ALFA sub-detector of ATLAS. Using a fit to the diffe

Techno-economic evaluation of 2nd generation bioethanol production from sugar cane bagasse and leaves integrated with the sugar-based ethanol process

Background: Bioethanol produced from the lignocellulosic fractions of sugar cane (bagasse and leaves), i.e. second generation (2G) bioethanol, has a promising market potential as an automotive fuel; however, the process is still under investigation on pilot/demonstration scale. From a process perspective, improvements in plant design can lower the production cost, providing better profitability an

Crosstalk between colorectal cancer cells and tumour-associated macrophages

Popular Abstract in English Colorectal cancer (CRC) is a cancer caused by uncontrolled cell growth in colon or rectum. CRC is the third most common cancer and the fourth leading cause of cancer related death in the world. It is a multifactorial disease, both genetic predisposition and environmental play a role in the development of CRC. CRC is closely linked to chronic inflammation. Patients with Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of death from cancer worldwide. People suffering from inflammatory bowel disease, such as Crohns’ disease and ulcerative colitis, are at an increased risk of developing CRC. The development of CRC is highly influenced by the tumour microenvironment. Tumour cells are able to recruit macrophages and change their beh

Ncf1 Provides a Reactive Oxygen Species-Independent Negative Feedback Regulation of TLR9-Induced IL-12p70 in Murine Dendritic Cells

Permanent exposure to pathogens requires decisions toward tolerance or immunity as a prime task of dendritic cells. The molecular mechanisms preventing uncontrolled immune responses are not completely clear. We investigated the regulatory function of Ncf1, an organizing protein of NADPH oxidase, in the signaling cascade of Toll-like receptors. TLR9-stimulated spleen cells from both Ncf1-deficient