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Silica seed particles improve the efficiency and throughput of nanoparticle acoustic trapping

Silica has rarely been used as a seed particle material in acoustic trapping of nanoparticles. Here we use fluorescent nanoparticles, which are frequently used as a model system, to demonstrate that throughput and nanoparticle trapping efficiency can be improved by using silica seed particles as opposed to traditionally used polystyrene seed particles. The 10 times larger dipole scattering coeffic

Reconfiguring a Plane-Parallel Transmission Ionization Chamber to Extend the Operating Range into the Ultra-High Dose-per-pulse Regime

This study aims to investigate the feasibility of enhancing the charge collection efficiency (CCE) of a transmission chamber by reconfiguring its design and operation. The goal was to extend the range of dose-per-pulse (DPP) values with no or minimal recombination effects up to the ultra-high dose rate (UHDR) regime. The response of two transmission chambers, with electrode distance of 1 mm and 0.

A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile

The complement system plays a central role in the pathogenesis of Systemic Lupus Erythematosus (SLE), but most studies have focused on the classical pathway. Ficolin-3 is the main initiator of the lectin pathway of complement in humans, but its role in systemic autoimmune disease has not been conclusively determined. Here, we combined biochemical and genetic approaches to assess the contribution o

Hypertension in Pregnancy Among Immigrant and Swedish Women : A Cohort Study of All Pregnant Women in Sweden

BACKGROUND: Little is known about risks of hypertensive disorders of pregnancy in both first-and second-generation immigrant women in Europe and other Western countries; such knowledge may help elucidate the influence of genetic versus social factors on such risks. We aimed to study both first-and second-generation immigrant women for the presence of all types of hypertension (preexisting hyperten

Macromolecular characterization of high β-glucan oat lines

Oat (Avena sativa) is a cereal grain rich in fibers, proteins, vitamins and minerals. Oats have been linked to several health benefits, such as lowering blood cholesterol levels, counteracting cardiovascular disease and regulating blood sugar levels. This study aimed to characterize two new oat lines with high β-glucan content emanating from ethyl methyl sulphonate mutagenesis on the Lantmännen el

Three-pion scattering in Chiral Perturbation Theory

We present the results on the relativistic six-pion scattering amplitude at low energy, calculated at O(p4) within the framework of the massive O(N) nonlinear sigma model extended to the next-to-leading order in the chiral counting. For N = 3, this approach corresponds to the two(quark)-flavor Chiral Perturbation Theory. We also present the expressions for the pion mass, pion decay constant and th

Modeling Atmospheric Transport of Cosmogenic Radionuclide 10Be Using GEOS-Chem 14.1.1 and ECHAM6.3-HAM2.3 : Implications for Solar and Geomagnetic Reconstructions

A prerequisite to applying 10Be in natural archives for solar and geomagnetic reconstructions is to know how 10Be deposition reflects atmospheric production changes. However, this relationship remains debated. To address this, we use two state-of-the-art global models GEOS-Chem and ECHAM6.3-HAM2.3 with the latest beryllium production model. During solar modulation, both models suggest that 10Be de

Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias

Background and Clonal haematopoiesis of indeterminate potential (CHIP), the age-related expansion of blood cells with preleukemic mutaAims tions, is associated with atherosclerotic cardiovascular disease and heart failure. This study aimed to test the association of CHIP with new-onset arrhythmias.Methods UK Biobank participants without prevalent arrhythmias were included. Co-primary study outcome

Reassessment of Archaeooides based on new material from the Fortunian (early Cambrian) of China infers algal affinity

Archaeooides originally refers to a group of early Cambrian globular microfossils with regularly arranged nodular surface ornaments, and of a diameter ranging from less than 400 μm to more than 2 mm. The traditional taxonomy assigns all Archaeooides-like microfossils to a single morphotaxon, Archaeooides granulatus, irrespective of their differences in size and surface ornamentation. Archaeooides

Inferring the Redshift of More than 150 GRBs with a Machine-learning Ensemble Model

Gamma-ray bursts (GRBs), due to their high luminosities, are detected up to a redshift of 10, and thus have the potential to be vital cosmological probes of early processes in the Universe. Fulfilling this potential requires a large sample of GRBs with known redshifts, but due to observational limitations, only 11% have known redshifts (z). There have been numerous attempts to estimate redshifts v

Substantial Differences in Crop Yield Sensitivities Between Models Call for Functionality-Based Model Evaluation

Crop models are often used to project future crop yield under climate and global change and typically show a broad range of outcomes. To understand differences in modeled responses, we analyzed modeled crop yield response types using impact response surfaces along four drivers of crop yield: carbon dioxide (C), temperature (T), water (W), and nitrogen (N). Crop yield response types help to underst

Uncovering power asymmetries in North-South research collaborations – An example from sustainability research in Tanzania

North - South collaboration between scientists and collaborators is increasingly prominent and promoted in research. This study examines power dynamics within a North-South research collaboration project conducted between institutions in Tanzania and Germany. The research design is guided by postcolonial considerations of knowledge production and seeks to amplify underrepresented voices from the S

Colonization of a Novel Host Plant Reduces Phenotypic Variation

Understanding the evolution of evolvability—the evolutionary potential of populations—is key to predicting adaptation to novel environments. Despite growing evidence that evolvability structures adaptation, it remains unclear how adaptation to novel environments in turn influences evolvability. Here we address the interplay between adaptation and evolvability in the peacock fly Tephritis conura, w

Empowering macrophages : the cancer fighters within the tumour microenvironment in mantle cell lymphoma

In Mantle Cell Lymphoma (MCL), the role of macrophages within the tumour microenvironment (TME) has recently gained attention due to their impact on prognosis and response to therapy. Despite their low absolute number in MCL tumour tissue, recent findings reveal an association between the levels of macrophages and prognosis, consistent with trends observed in other lymphoma subtypes. M2-like macro

Conviviality in Burgaz : Living, Loving and Fighting on a Diverse Island in Istanbul

This open access book tells stories of conviviality, solidarity, and everyday management of conflicts and tensions, by building on original, long-term ethnographic research (fourteen months in 2009-2010, followed by fieldwork trips until now) on Burgaz, an island home to more than twenty ethnic and religious groups from different socio-economic backgrounds. The island provides an excellent case st

Functional and molecular 3D mapping of angiosarcoma tumor using non-invasive laser speckle, hyperspectral, and photoacoustic imaging

PURPOSE: The gold standard for skin cancer diagnosis is surgical excisional biopsy and histopathological examination. Several non-invasive diagnostic techniques exist, although they have not yet translated into clinical use. This is a proof-of-concept study to assess the possibility of imaging an angiosarcoma in the periocular area.METHODS: We use laser speckle, hyperspectral, and photoacoustic im

Machine learning evaluation for identification of M-proteins in human serum

Serum electrophoresis (SPEP) is a method used to analyze the distribution of the most important proteins in the blood. The major clinical question is the presence of monoclonal fraction(s) of antibodies (M-protein/paraprotein), which is essential for the diagnosis and follow-up of hematological diseases, such as multiple myeloma. Recent studies have shown that machine learning can be used to asses