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Ewing's sarcoma treatment in Scandinavia 1984-1990--ten-year results of the Scandinavian Sarcoma Group Protocol SSGIV

A report on the long-term follow up of the first cooperative Scandinavian Sarcoma Group study in Ewing's sarcoma of bone is presented. Fifty-two previously untreated patients entered the study between 1984 and 1990. Half of the tumors were located in the extremities and one quarter in the pelvis. The combined modality treatment consisted of 5 cycles of chemotherapy--including vincristine, methotre

GPR40 is expressed in glucagon producing cells and affects glucagon secretion.

The free fatty acid receptor, GPR40, has been coupled with insulin secretion via its expression in pancreatic beta-cells. However, the role of GPR40 in the release of glucagon has not been studied and previous attempts to identify the receptor in alpha-cells have been unfruitful. Using double-staining for glucagon and GPR40 expression, we demonstrate that the two are expressed in the same cells in

Balanced truncation of linear time-varying systems

In this paper balanced truncation of linear time-varying systems is studied in discrete and continuous time. Based on relatively basic calculations with time-varying Lyapunov equations/inequalities we are able to derive both upper and lower error bounds for the truncated models. These results generalize well-known time-invariant formulas. The case oftime-varying state dimension is considered. Inpu

Thermal versus mechanical unfolding of ubiquitin

The authors studied the temperature-induced unfolding of ubiquitin by all-atom Monte Carlo simulations. The unfolding behavior is compared with that seen in previous simulations of the mechanical unfolding of this protein, based on the same model. In mechanical unfolding, secondary-structure elements were found to break in a quite well-defined order. In thermal unfolding, the authors saw somewhat

Spectroscopic units in conjugated polymers: A quantum chemically founded concept?

In conjugated polymers the concept of spectroscopic units belonging to different spatial segments of the chain, which are responsible for the spectroscopic properties of the polymer, has been used to explain the spectral heterogeneity and the excitation migration by (Forster type) hopping transfer. In the present work we study the possible mechanism of segmentation of polythiophene into spectrosco

Quantitative relationship between SOI and observed precipitation in southern Korea and Japan by nonparametric approaches

Several studies have tried to link southern oscillation index (Sol) and observed precipitation in Korea and Japan. However, so far no clear relationship between the Sol and the precipitation in the area has been found. In the present study, categorized Sol are used to reveal quantitative and statistically significant influence on monthly precipitation at Busan in Korea and at Fukuoka in Japan. Mon

Growth and interactions of arbuscular mycorrhizal fungi in soils from limestone and acid rock habitats

Arbuscular mycorrhizal (AM) development in different soil types, and the influence of AM fungal hyphae on their original soil were investigated. Plantago lanceolata, which can grow in soils of a very wide pH range, was grown in two closely related limestone soils and an acid soil from rock habitats. Plants were colonised by the indigenous AM fungal community. The use of compartmented systems allow

Clinical experiences with desmopressin for long-term treatment of nocturia

Purpose: To our knowledge we report the first long-term use of desmopressin for nocturia. Patients previously responding to desmopressin in short-term studies were enrolled in this long-term open label study. Materials and Methods: Patients received treatment for 10 or 12 months with the optimal desmopressin dose (0.1, 0.2 or 0.4 mg orally at bedtime). Patients were followed a further month withou

Tuberculosis mortality during a civil war in Guinea-Bissau

CONTEXT: Tuberculosis (TB) is an increasing global problem, despite effective drug therapies. Access to TB therapy during conflict situations has not been studied. OBJECTIVE: To determine the effect of irregular TB treatment due to an armed conflict in Guinea-Bissau, West Africa. DESIGN, SETTING, AND PATIENTS: Ongoing retrospective cohort study conducted in the capital city of Bissau among 101 pat

Stationary NOx storage and reduction experiments on a heavy-duty diesel engine rig using a bypass system

This work concerns exhaust gas cleaning for heavy-duty diesel engines by means of NOx storage and redn. technol. A full-scale engine rig has been constructed, and stationary NOx redn. tests performed. In the NOx storage and redn. approach, NOx is stored on a BaO surface as Ba(NO3)2 under long lean conditions and desorbed and reduced under short rich conditions. The rich conditions are created by i

Charge and energy transfer in binaphthalene molecule with two spiropyran units used for chiral molecular switches and logic gates

A new binaphthalene molecule with two spiropyran units used for chiral molecular switches and logic gates was synthesized and chaxacterized.(12) In this paper, charge and energy transfer in binaphthalene molecule with two spiropyran units are theoretically investigated with quantum chemistry method, as well as 2D and 3D real space analysis methods, since molecule construction with photoinduced ele

Structure Functions and general final state properties in the linked dipole chain model

We have in an earlier paper, [1], presented a generalization, the Linked Dipole Chain Model LDC, of the model developed by Ciafaloni-Catani-Fiorani-Marchesini, [2], to decribe the structure functions and the states in Deep Inelastic Scattering events. In this paper we would like to present an investigation of a set of general features of the LDC Model, viz the behaviour of the structure functions

End-to-side nerve repair - A study in the forelimb of the rat

Popular Abstract in Swedish De perifera nervstammarna i extremiteterna förmedlar signaler, dels till muskler, dels från känselkroppar som är belägna i bl a huden. Nervstammarna kan av olika orsaker utsättas för skador orsakade av vassa eller skärande föremål eller av olika typer av slitvåld. Nervskador ger ett mycket stort handikapp för den enskilde patienten som förlorar muskelfunktion och känselNerve injuries have a profound impact on individuals, suffering for the patients and induce cost for society. When dealing with severe nerve injuries that create a gap between nerve segments or when the injury is at the brachial plexus level, the clinical alternatives are limited. The brachial plexus model and its branches in the forelimb was evaluated as an experimental model for studies of nerve

Unified model of fractal conductance fluctuations for diffusive and ballistic semiconductor devices

We present an experimental comparison of magnetoconductance fluctuations measured in the ballistic, quasiballistic, and diffusive scattering regimes of semiconductor devices. In contradiction to expectations, we show that the spectral content of the magnetoconductance fluctuations exhibits an identical fractal behavior for these scattering regimes and that this behavior is remarkably insensitive t