Inversion efficiency model yields improved accuracy in MP2RAGE-based T1-mapping in the human brain at 7.0T
Introduction: Estimation of the longitudinal relaxation time T1 from the MP2RAGE pulse sequence is based on a monoexponential signal evolution model. However, magnetization transfer caused by the inversion pulse induces a fast relaxation component which appears as a reduction in the efficiency of the inversion. This may explain the underestimation of T1 derived from MP2RAGE. To address this system