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Dynamic Risk Management in Air Traffic Management System Failures

Context This research looks at managing uncertainty and recovery processes following failure of a sociotechnical system. The provision of Air Traffic Services (ATS) is an essential service that must continue to function supporting at a minimum; medical flights, search and rescue operations, humanitarian aid, State and military flights (as demonstrated during the recent global pandemic). Purpose Th

The frontlines of contested urbanism : Mega-projects and mega-resistances in Dharavi

Currently, there appears to be an unhealthy disjunction between grand expectations and acknowledged reality in the face of urban transformations underway throughout the world. Drawing on the "right to the city" discourses, adopting a Lefebvrian approach to the production of space, and a critical regionalist approach to housing and the built environment, the article explores the conceptual analytic

Are green cities healthy and equitable? Unpacking the relationship between health, green space and gentrification

While access and exposure to green spaces has been shown to be beneficial for the health of urban residents, interventions focused on augmenting such access may also catalyse gentrification processes, also known as green gentrification. Drawing from the fields of public health, urban planning and environmental justice, we argue that public health and epidemiology researchers should rely on a more

From Occupying Plazas to Recuperating Housing : Insurgent Practices in Spain

Urban insurgencies have spread across the globe like wildfire in recent years. The indignado plaza occupations in Spain are often cited as beacons of popular and widespread dissent. This article argues that urban insurgencies with the highest emancipatory potential in Spain today are found in the practices of the housing rights movement—the Plataforma de Afectados por la Hipoteca (PAH, or Platform

The use and usefulness of point-of-care tests in patients with pharyngotonsillitis – an observational study in primary health care

Background: Rapid antigen detection tests (RADT) for Group A streptococci (GAS) and point-of-care tests for C-reactive protein (CRP) are commonly used in patients with pharyngotonsillitis in Sweden and Denmark although CRP testing is not supported by guidelines. We aimed to describe (1) the proportion of patients tested with RADT and/or CRP, (2) the relation between test results and antibiotic pre

Highly efficient eco-friendly sodium titanate sorbents of Cs(i), Sr(ii), Co(ii) and Eu(iii) : synthesis, characterization and detailed adsorption study

Development of useful all-around materials which can quickly and efficiently adsorb radionuclides in response to environmental radioactive contamination is an urgent research objective. In response to this need, our team developed a simple preparation method for stable sodium titanates which can serve as efficient agents for removal of radionuclides from water. With an emphasis on an environmental

The predictive value of highly malignant EEG patterns after cardiac arrest : evaluation of the ERC-ESICM recommendations

Purpose: The 2021 guidelines endorsed by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) recommend using highly malignant electroencephalogram (EEG) patterns (HMEP; suppression or burst-suppression) at > 24 h after cardiac arrest (CA) in combination with at least one other concordant predictor to prognosticate poor neurological outcome. We evalu

Pre- and Postoperative Antioxidant Use, Aryl Hydrocarbon Receptor (AhR) Activation and Clinical Outcome in Different Treatment Groups of Breast Cancer Patients

BACKGROUND: Cancer patients often use antioxidants that may interact with adjuvant treatments. The purpose was to investigate pre- and postoperative antioxidant use in relation to clinicopathological characteristics and prognosis in different breast cancer treatment groups.METHODS AND PATIENTS: Pre- and postoperative antioxidant (vitamin A, C, E, carotenoids, or Q10) or multivitamin use was self-r

Brain energy metabolism : A roadmap for future research

Although we have learned much about how the brain fuels its functions over the last decades, there remains much still to discover in an organ that is so complex. This article lays out major gaps in our knowledge of interrelationships between brain metabolism and brain function, including biochemical, cellular, and subcellular aspects of functional metabolism and its imaging in adult brain, as well

All-Cause and Cause-Specific Mortality among Individuals with Hypochondriasis

Importance: Hypochondriasis, also known as health anxiety disorder, is a prevalent, yet underdiagnosed psychiatric disorder characterized by persistent preoccupation about having serious and progressive physical disorders. The risk of mortality among individuals with hypochondriasis is unknown. Objective: To investigate all-cause and cause-specific mortality among a large cohort of individuals wit

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies

The main protease Mpro, nsp5, of SARS-CoV-2 (SCoV2) is one of its most attractive drug targets. Here, we report primary screening data using nuclear magnetic resonance spectroscopy (NMR) of four different libraries and detailed follow-up synthesis on the promising uracil-containing fragment Z604 derived from these libraries. Z604 shows time-dependent binding. Its inhibitory effect is sensitive to

Herrens år 1402

Det här är en roman; den femte av mina kriminalromaner om Thierry av Liège, vilka utspelar sig under Tyska ordens innehav av Gotland 1398-1408.

Long-term outcomes with haloperidol versus placebo in acutely admitted adult ICU patients with delirium

Purpose: We assessed long-term outcomes in acutely admitted adult patients with delirium treated in intensive care unit (ICU) with haloperidol versus placebo. Methods: We conducted pre-planned analyses of 1-year outcomes in the Agents Intervening against Delirium in the ICU (AID-ICU) trial, including mortality and health-related quality of life (HRQoL) assessed by Euroqol (EQ) 5-dimension 5-level