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Upregulated TRPC1 Channel in Vascular Injury In Vivo and Its Role in Human Neointimal Hyperplasia.

Occlusive vascular disease is a widespread abnormality leading to lethal or debilitating outcomes such as myocardial infarction and stroke. It is part of atherosclerosis and is evoked by clinical procedures including angioplasty and grafting of saphenous vein in bypass surgery. A causative factor is the switch in smooth muscle cells to an invasive and proliferative mode, leading to neointimal hype

Electrochromic devices operating with electrolytes based on boronate ester compounds and various alkali metal salts

Various polymer electrolytes based on boronate esters and different lithium and sodium salts have been evaluated in electrochromic (EC) devices based on WO3 films. The results showed that the ionic conductivity of the electrolytes was not the most important parameter for the colouration performance of these devices. The use of solid electrolytes containing LiClO4 resulted in a higher colouration p

Lack of relation between glycosylated haemoglobin concentrations and number of daily insulin injections: cross sectional study in care of ambulatory diabetes

Diabetic treatment aims at achieving a normal blood glucose concentration as reflected by the glycosylated haemoglobin concentration. Intensive treatment by insulin pump or multiple insulin injections is thought to achieve this. In an unselected group of outpatient diabetics metabolic control was the same after one, two, three, or more injections, which suggests that the mode of treatment was opti

Giorgio Agamben and the spatialities of the camp: An introduction

The Italian political philosopher Giorgio Agamben's conclusion that the camp has replaced the city as the biopolitical paradigm of the West is as difficult to digest as it is easy to see how it responds to contemporary political tendencies in the world today. In this introduction to this theme issue on Giorgio Agamben and the spatialities of the camp, a detailed exposition emulating the structure

Methodological improvements for measuring eicosanoids and cytokines in exhaled breath condensate.

Background: Exhaled breath condensate (EBC) is simple to cottect and as such a non-invasive method that has attracted substantial interest in the last few years. However, several methodological concerns have been raised and it has been difficult to reproduce results between different centres. Because of low concentrations of inflammatory markers, potential loss in the sampling system may have grea

Study of restriction fragment length polymorphism in the cystatin C gene of elderly patients with dementia and aged Down's syndrome patients

Using a full length cystatin C cDNA probe and the Alu I restriction enzyme a total of 33 patients with senile dementia, Alzheimer type and 31 Down's syndrome patients have been investigated for the presence of the 630 bp Alu I restriction fragment length polymorphism in the cystatin C gene detected in Icelandic patients with hereditary cystatin C amyloid angiopathy. Results showed that all the pat

Uniform spectral radius and compact Gelfand transform

We consider the quantization of inversion in commutative p-normed quasi-Banach algebras with unit. The standard questions considered for such an algebra A with unit e and Gelfand transform x bar right arrow (x) over cap are: (i) Is K-nu = sup{parallel to(e - x)(-1)parallel to(p) : x is an element of A, parallel to x parallel to(p)

Control and Rent-Seeking: The Role of the State in the Thai Cassava Industry

What we can conclude from this study is that the state and the market are not perfect substitutes in allocating resources and sustaining economic development separately. The case of the Thai cassava industry seems to suggest that the Thai state is not benevolent, but predatory in nature. The central point is that the Thai state cannot be simply seen as weak and predatory without understanding the

Signal transduction and calcium sensitivity of smooth muscle contraction

Popular Abstract in Swedish Glatt muskulatur ingår i flera fysiologiskt viktiga organsystem och är involverade i flera sjukdomsprocesser. Glatt muskelkontraktion regleras av variationer i intracellulärt calcium; höjda nivåer aktiverar kinaset MLCK som fosforylerar myosin och initierar kontraktion. Myosin fosfatas (MLCP) avfosforylerar myosin vilket leder till relaxation. Flera intracellulära signaSmooth muscles are components of several physiologically important organs and often involved in disease. Smooth muscle contraction is regulated by variations in intracellular [Ca2+]; increased levels activate the myosin light chain kinase (MLCK) which phosphorylates myosin and initiates contraction. Myosin phosphatase (MLCP) dephosphorylates myosin and promotes relaxation. Several cellular signali

The n ->pi* electronic transition in microsolvated formaldehyde. A coupled cluster and combined coupled cluster/molecular mechanics study

In this article, we study the n - pi* electronic transition in aqueous microsolvated formaldehyde using the coupled cluster (CC) and coupled cluster/molecular mechanics (CC/MM) methods. The CC models used are the coupled cluster singles and doubles (CCSD) and the coupled cluster second-order approximate singles and doubles (CC2) methods. The CC/MM model includes electrostatic and mutual polarizati

Development of a tRNA-Synthetase Microarray for Protein Analysis

Proteins are composed of 20 different amino acids. In the translation process, each of these 20 amino acids is specifically recognized by their cognate aminoacyl-tRNA synthetase. The fidelity of this recognition system is essential if translation is to function properly. The development of an in vitro system based on this recognition scheme would make a powerful analytical tool with which to analy

Nanomagnetic and Micromagnetic Properties of Rocks Minerals and Sulphide Oxidation Products

Magnetic and related properties of rocks and products from oxidation of sulphide minerals have been investigated with magnetisation measurements (rocks and oxidation products), magnetic force microscopy (rocks), scanning electron microscopy (rocks and oxidation products), transmission electron microscopy (oxidation products), Mössbauer spectroscopy (oxidation products) and powder X-ray diffraction