Published 12 January 2020 When imputing missing baseline values, all methods underestimated equally the true value, but LME3 and MICE correctly estimated remission and low disease activity rates. When imputing missing follow-up values at 6, 12, or 24 months, NAO provided the least biassed estimate of the mean disease activity and corresponding remission rate. These results were not affected by the

https://www.lupop.lu.se/article/imputing-missing-data-function-and-disease-activity-rheumatoid-arthritis-registers-what-best - 2025-01-10

Published 12 January 2020 The score included 31 conditions selected from a list of 65 candidates whose weights were assigned according to the Cox model coefficients. The model was built from a sample of 5.4 million National Health Service (NHS) beneficiaries from the Italian Lombardy Region and applied to the remaining 2.7 million NHS beneficiaries. Predictive performance was assessed by discrimin

https://www.lupop.lu.se/article/new-population-based-risk-stratification-tool-was-developed-and-validated-predicting-mortality - 2025-01-10

Published 13 January 2020 Previous simulation studies of the case–control study design using incidence density sampling, which required individual matching for time, showed biased estimates of association from conditional logistic regression (CLR) analysis; however, the reason for this is unknown. Separately, in the analysis of case–control studies using the exclusive sampling design, it has been

https://www.lupop.lu.se/article/bias-control-analysis-case-control-studies-incidence-density-sampling - 2025-01-10

Published 13 January 2020 In Sweden, the patients’ diagnoses are recorded in administrative registers. The research value of these registers is determined by their diagnostic validity, that is, if the diagnosis recorded meets the relevant diagnostic criteria. The aim of the study was to assess the validity of post-traumatic stress disorder (PTSD)-diagnoses as compared with case notes in medical re

https://www.lupop.lu.se/article/validation-study-randomly-selected-cases-ptsd-diagnoses-identified-swedish-regional-database - 2025-01-10

Published 14 January 2020 Estimating the number of individuals living in a country is an essential task for demographers. This study assesses the potential bias in estimating the size of different migrant populations due to over-coverage in population registers. Over-coverage-individuals registered but not living in a country-is an increasingly pressing phenomenon; however, there is no common unde

https://www.lupop.lu.se/article/over-coverage-population-registers-leads-bias-demographic-estimates - 2025-01-10

Published 14 January 2020 A healthy lifestyle has been shown to reduce the risk of coronary artery disease (CAD). The extent to which lifestyle influences the risk of CAD for people with pre-existing non-modifiable risk factors is less studied. We therefore examined the associations between a favorable lifestyle and incidence of CAD in population subgroups based on gender, age, educational level,

https://www.lupop.lu.se/article/favorable-lifestyle-lowers-risk-coronary-artery-disease-consistently-across-strata-non-modifiable - 2025-01-10

Published 15 January 2020 Selective participation may hamper the validity of population-based cohort studies. The resulting bias can be alleviated by linking auxiliary register data to both the participants and the non-participants of the study, estimating propensity scores for participation and correcting for participation based on these. However, registry holders may not be allowed to disclose s

https://www.lupop.lu.se/article/correcting-selective-participation-cohort-studies-using-auxiliary-register-data-without - 2025-01-10

Published 15 January 2020 New publication in The Lancet

https://www.lupop.lu.se/article/data-must-be-shared-also-researchers-outside-europe-0 - 2025-01-10

Published 10 January 2020 Monday January 13 at 9-12, we will have our very first LUPOP drop-in! Come to the Tornblad Building, have a look at the LUPOP office and ask questions on population studies! For address and directions, visit https://www.lupop.lu.se/tornblad. 

https://www.lupop.lu.se/article/first-lupop-drop - 2025-01-10

Published 19 December 2017 It is now open to proposals within the research areas health, working life and welfare. There are three kinds of grants to apply for: Project grants, junior research grants and postdoc grants. The deadline is the 1st of February. For more information about this, and the call for proposals regarding research on how to prevent sick leave and promote the return to work, see

https://www.lupop.lu.se/article/fortes-open-call-proposals-now-open - 2025-01-10

Published 13 January 2020 Länksamling hos SND Läs mer här.

https://www.lupop.lu.se/article/internationella-resurser-att-hitta-data-och-relaterade-tjanster - 2025-01-10

Published 16 January 2020 The effect of neighbourhood deprivation on CHD might depend on age. Accounting for individuals’ baseline age may therefore be important for understanding neighbourhood environmental effects on the development of CHD over time. However, because of high correlation of neighbourhood deprivation over time, single-point-in-time assessments may be adequate for CHD risk predicti

https://www.lupop.lu.se/article/accumulated-neighbourhood-deprivation-and-coronary-heart-disease-nationwide-cohort-study-sweden - 2025-01-10

Published 16 January 2020 The number of chronic conditions and medications are important for the odds of hospitalisation, while the use of PIM, according to the definition used in this study, was no significant in the full model. New publication in BMJ Journals

https://www.lupop.lu.se/article/importance-potentially-inappropriate-medications-number-chronic-conditions-and-medications-risk - 2025-01-10

Published 17 January 2020 Coronary artery disease (CAD) is more frequent among individuals with dysglycemia. Preventive interventions for diabetes can improve cardiometabolic risk factors (CRFs), but it is unclear whether the benefits on CRFs are similar for individuals at different genetic risk for CAD. We built a 201-variant polygenic risk score (PRS) for CAD and tested for interaction with diab

https://www.lupop.lu.se/article/interaction-between-type-2-diabetes-prevention-strategies-and-genetic-determinants-coronary-artery - 2025-01-10

Published 17 January 2020 The caesarean section rate has increased rapidly in Sierra Leone, but the distribution remains uneven. Caesarean section mortality is high, but there is wide variation. More access to caesarean sections for maternal and neonatal complications is needed in underserved areas, and expansion should be coupled with efforts to limit late presentation, to offer assisted vaginal

https://www.lupop.lu.se/article/rate-and-perioperative-mortality-caesarean-section-sierra-leone - 2025-01-10

Published 18 January 2020 Survival without major comorbidities among persons born extremely preterm (22-27 weeks), very preterm (28-33 weeks), late preterm (34-36 weeks), or early term (37-38 weeks), compared with full-term (39-41 weeks). Comorbidities were defined using the Adolescent and Young Adult Health Outcomes and Patient Experience (AYA HOPE) Comorbidity Index, which includes conditions th

https://www.lupop.lu.se/article/prevalence-survival-without-major-comorbidities-among-adults-born-prematurely - 2025-01-10

Published 18 January 2020 In this large national cohort, preterm birth was associated with an increased risk of lipid disorders in early- to midadulthood. Persons born prematurely may need early preventive evaluation and long-term monitoring for lipid disorders to reduce their future cardiovascular risks. New publication in PLOS Medicine

https://www.lupop.lu.se/article/association-preterm-birth-lipid-disorders-early-adulthood-swedish-cohort-study - 2025-01-10

Published 19 January 2020 Alcohol use disorders (AUD) is well known to aggregate in families and is associated with socioeconomic status (SES). The objective was to study the effect of education, income and neighborhood SES in adulthood on AUD, and to explore whether the potential associations were confounded by shared familial factors, by using a co-relative control design. New publication in PLO

https://www.lupop.lu.se/article/socioeconomic-status-and-alcohol-use-disorders-across-lifespan-co-relative-control-study - 2025-01-10

Published 19 January 2020 Short sleep duration (<8 hours) was associated with poor self-reported health, increased screen time, and nighttime texting among respondents. These results provide information for parents, educators, and school health professionals to encourage young people to adopt healthy screen habits and sleep hygiene. New publication in SAGE Journals

https://www.lupop.lu.se/article/sleep-duration-associated-self-reported-overall-health-screen-time-and-nighttime-texting-among - 2025-01-10

Published 20 January 2020 To ascertain the mortality rate and causes of death in patients with systemic lupus erythematosus (SLE) within a defined region in southern Sweden during the time period 1981–2014 and determine whether these have changed over time. New publication in SAGE Journals

https://www.lupop.lu.se/article/good-survival-rates-systemic-lupus-erythematosus-southern-sweden-while-mortality-rate-remains - 2025-01-10