By johanna [dot] sandahl [at] med [dot] lu [dot] se (Johanna Sandahl) - published 25 November 2020 Vinay Swaminathan studies cell movement in health and disease. “To understand how cells get hijacked in diseases, we need to understand how cells work.” Vinay Swaminathan is one of the researchers at Wallenberg Centre for Molecular Medicine at Lund University (WCMM LU). This autumn, every week, we pr

https://www.medicine.lu.se/article/meet-weeks-wallenberg-researcher-vinay-swaminathan - 2025-03-14

By tove [dot] gilvad [at] med [dot] lu [dot] se (Tove Gilvad) - published 25 November 2020 Martin Magnusson and Amra Jujic (Photo: Tove Gilvad) Diabetes is currently treated using incretin hormones to reduce the risk of cardiovascular disease and other medical issues that the illness can trigger. Now researchers from Lund University in Sweden have noted new links between these hormones and arterio

https://www.medicine.lu.se/article/incretin-hormone-levels-linked-arteriosclerosis - 2025-03-14

By johanna [dot] sandahl [at] med [dot] lu [dot] se (Johanna Sandahl) - published 2 December 2020 João Duarte. Photo: Kennet Ruona João Duarte is linking cognitive impairment and diabetes. “Our findings might one day contribute to the development of metabolic or brain disease therapeutics.” João Duarte is one of the researchers at Wallenberg Centre for Molecular Medicine at Lund University (WCMM L

https://www.medicine.lu.se/article/meet-weeks-wallenberg-researcher-joao-duarte - 2025-03-14

By johanna [dot] sandahl [at] med [dot] lu [dot] se (Johanna Sandahl) - published 9 December 2020 Anja Meissner. Photo: Kennet Ruona Anja Meissner is looking for new treatments for cardiovascular diseases. “We are interested in understanding processes involved in disease onset and progression.” Anja Meissner is one of the researchers at Wallenberg Centre for Molecular Medicine at Lund University (

https://www.medicine.lu.se/article/meet-weeks-wallenberg-researcher-anja-meissner - 2025-03-14

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 11 December 2020 Mikael Dolsten (Photo: Pfizer) Mikael Dolsten, head of research at Pfizer, who led the development of Pfizer’s and BioNTech’s Covid-19 vaccine, will take up the appointment of visiting professor of Pharmacology at Lund University in Sweden on 1 January 2021. “During my years as a student and researcher in Lund

https://www.medicine.lu.se/article/mikael-dolsten-appointed-visiting-professor-lund-university - 2025-03-14

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 15 December 2020 It has long been known that the choice of shoe, surface and type of sport can all be contributing factors when someone suffers an anterior cruciate ligament rupture. Researchers at Lund University in Sweden have now observed that genes also play a decisive role. Karin Magnusson. By analysing data from the Swed

https://www.medicine.lu.se/article/genes-play-role-common-knee-injury - 2025-03-14

By agata [dot] garpenlind [at] med [dot] lu [dot] se (Agata Garpenlind) - published 17 December 2020 Sebastian Albinsson and Fatima Daoud. Photo: Agata Garpenlind Researchers at Lund University have shown that a group of proteins are crucial for smooth muscle function in the gastrointestinal tract. A lack of these proteins leads to a lethal condition called intestinal pseudo obstruction in mice. T

https://www.medicine.lu.se/article/impaired-bowel-movement-due-lack-protein - 2025-03-14

By agata [dot] garpenlind [at] gmail [dot] com (Agata Garpenlind) - published 19 January 2021 Sinem Tas. Photo: Agata Garpenlind The fight against COVID-19 continues. In Lund, researchers have been awarded a large Vinnova grant to identify a compound that could be used to prevent viral infection, and thus save lives. The project is a co-operation between preclinical, clinical researchers and a com

https://www.medicine.lu.se/article/new-interdisciplinary-co-op-between-researchers-healthcare-and-industry-formed-fight-virus - 2025-03-14

By agata [dot] garpenlind [at] gmail [dot] com (Agata Garpenlind) - published 19 January 2021 Pontus Gourdon in the lab. Photo: Magnus Bergström Lund University represents one of the most attractive locations within structural biology in entire Northern Europe, says Pontus Gourdon, who has been awarded a Wallenberg Academy Fellows prolongation grant 2020 from Knut and Alice Wallenberg Foundation.

https://www.medicine.lu.se/article/adopting-long-term-research-approach-thanks-prolongation-grant - 2025-03-14

By agata [dot] garpenlind [at] gmail [dot] com (Agata Garpenlind) - published 19 January 2021 Harmful variants in cellular networks divided by different forms of cancer. Lund researcher Mauno Vihinen has received a grant from the Cancer Foundation to develop AI methods that in the long run enable improved cancer diagnosis. One of the researchers who has received a grant from the Cancer Foundation

https://www.medicine.lu.se/article/improved-and-tailored-prediction-methods-cancer - 2025-03-14

Published 17 September 2021 Photo: Pixabay / Arek Socha 1) We found 15 national/regional registries of congenital heart disease worldwide. 2) Registry coverage ranged from 25 to 100% of all eligible cases. 3) The best registries contain demographic, clinical, physical, and laboratory data. 4) Regular verification is essential for quality data and valid statistical findings. Read the paper at https

https://www.lupop.lu.se/article/national-and-regional-registries-congenital-heart-diseases-strengths-weaknesses-and-opportunities - 2025-03-14

Published 18 September 2021 Quantitative bias analyses allow researchers to adjust for uncontrolled confounding, given specification of certain bias parameters. When researchers are concerned about unknown confounders, plausible values for these bias parameters will be difficult to specify. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/09000/The_Importance_of_M…

https://www.lupop.lu.se/article/importance-making-assumptions-bias-analysis - 2025-03-14

Published 18 September 2021 Photo: Pixabay / Colin Behrens The benefits of using data from national registers as endpoints in epidemiological studies include faster, less resource-intensive access to nationwide data and considerably lower loss to follow-up, compared to manual data collection in a limited geographical area. Read the paper at https://www.dovepress.com/validating-acute-myocardial-inf

https://www.lupop.lu.se/article/validating-acute-myocardial-infarction-diagnoses-national-health-registers-use-endpoint-research - 2025-03-14

Published 19 September 2021 The integrative data approach is an effective way to conduct cancer research assessing multilevel factors on cancer outcomes among small populations. Read the paper at https://cebp.aacrjournals.org/content/30/8/1506.long

https://www.lupop.lu.se/article/integrating-electronic-health-record-cancer-registry-and-geospatial-data-study-lung-cancer-asian - 2025-03-14

Published 19 September 2021 Photo: Pixabay / www_slon_pics This first publication of the Austrian Society of Esophageal Surgery shows that the outcome of esophageal surgery for cancer in Austria compares well with that of renowned international centers. However, a more comprehensive approach including as many national centers as possible will improve outcome research, offer quality management, and

https://www.lupop.lu.se/article/esophageal-resection-austria-preparing-national-registry - 2025-03-14

Published 20 September 2021 Photo: Pixabay / geralt The CARTR Plus registry is a robust resource for ART data in Canada. It provides easily accessible aggregated data for Canadian fertility clinics, and it contains data that are internationally comparable. Read the paper at https://academic.oup.com/hropen/article/2020/3/hoaa022/5848715

https://www.lupop.lu.se/article/cartr-plus-creation-art-registry-canada - 2025-03-14

Published 20 September 2021 Photo: Pixabay / geralt Parameters representing adjusted treatment effects may be defined marginally or conditionally on covariates. The choice between a marginal or covariate-conditional parameter should be driven by the study question. However, an unappreciated benefit of marginal estimators is a reduction in susceptibility to finite-sample bias relative to the unpena

https://www.lupop.lu.se/article/decreased-susceptibility-marginal-odds-ratios-finite-sample-bias - 2025-03-14

Published 21 September 2021 Confounding, selection bias, and measurement error are well-known sources of bias in epidemiologic research. Methods for assessing these biases have their own limitations. Read the paper at https://journals.lww.com/epidem/Fulltext/2021/09000/Multiple_bias_Sensi…

https://www.lupop.lu.se/article/multiple-bias-sensitivity-analysis-using-bounds - 2025-03-14

Published 21 September 2021 Photo: Pixabay / Brian Merrill Monitoring survival in cancer is a common concern for patients, physicians, and public health researchers. The traditional cohort approach for monitoring cancer prognosis has a timeliness problem. In this paper, we propose a survivorship-period-cohort (SPC) model for examining the effects of survivorship, period, and year-of-diagnosis coho

https://www.lupop.lu.se/article/survivorship-period-cohort-model-cancer-survival-application-liver-cancer-taiwan-1997-2016 - 2025-03-14

Published 22 September 2021 Life-course epidemiology is useful for describing and analyzing complex etiological mechanisms for disease development, but existing statistical methods are essentially confirmatory, because they rely on a priori model specification. Read the paper at https://academic.oup.com/aje/article/190/9/1898/6189737

https://www.lupop.lu.se/article/data-driven-model-building-life-course-epidemiology - 2025-03-14