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The Impact of COVID-19 on Parkinson's Disease : A Case-Controlled Registry and Questionnaire Study on Clinical Markers and Patients' Perceptions

Introduction. Parkinson's disease (PD) is a neurodegenerative disease with motor and nonmotor symptoms. Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Objectives. To explore how COVID-19 affects motor, nonmotor, and general health aspects of PD and to map how PD patients perceive their change in symptoms since fa

Circular Economy regulation : An emerging research agenda

Circular Economy regulation is rapidly adopted at different levels of governance, including municipalities, private and industry standards, national law and supranational standard-setting. There are increasing demands from policymakers, businesses and civil society for theoretical insights and more knowledge on the effects of policies and laws ('policy learning'). However, despite this mounting in

Completeness of certain compact Lorentzian locally symmetric spaces

We show that a compact Lorentzian locally symmetric space is geodesically complete if the Lorentzian factor in the local de Rham–Wu decomposition is of Cahen–Wallach type or if the maximal flat factor is one-dimensional and time-like. Our proof uses a recent result by Mehidi and Zeghib and an earlier result by Romero and Sánchez.

Into the Metaverse: Technological Advances Shaping the Future of Consumer and Retail Marketing

This chapter explores how technological advances can shape our future consumption, marketing, and society. Using a McLuhanian theoretical lens, and the metaverse as an illustrative example of emerging technological development, the chapter unpacks the marketing and socio-political implications of technological advances. It delves into how brands have been using the current rendition of the metaver

Shigella IpaA mediates actin bundling through diffusible vinculin oligomers with activation imprint

Upon activation, vinculin reinforces cytoskeletal anchorage during cell adhesion. Activating ligands classically disrupt intramolecular interactions between the vinculin head and tail domains that bind to actin filaments. Here, we show that Shigella IpaA triggers major allosteric changes in the head domain, leading to vinculin homo-oligomerization. Through the cooperative binding of its three vinc

Introducing Space for Peace

Space for Peace is a Special Issue that advances the spatial turn in peace and conflict studies. It brings to the fore the purchase of using space as an analytic category by advancing spatial theorization and providing empirical case studies. This introduction draws out the main tenets of spatial approaches and responds to the question: Why space? Moreover, it outlines the chapters in the Special

Att skapa framtidens resande : 15 förutsättningar för lärande i innovationsarbete

Den här rapporten handlar om lärande från experiment och vänder sig till dig som arbetar med innovation i svenska regioner och kommuner. I fokus ligger frågor kring organisatoriskt lärande, som här förstås som ett medel för att uppnå strategisk förnyelse av en organisation. Lärande är således nära besläktat med förändring. Vår utgångspunkt är att allt lärande kan förstås som en form av översättnin

Radiological properties of neurological injury following acute type A aortic dissection repair

Objective: The study objective was to assess the radiological properties of acute type A aortic dissection–related neurological injuries and identify predictors of neurological injury. Methods: Our single-center, retrospective, observational study included all patients who underwent acute type A aortic dissection repair between January 1998 and December 2021. Multivariable analyses and Cox regress

Immigrants from more tolerant cultures integrate deeper into destination countries

We highlight a new factor behind integration: tolerance in the immigrants’ background culture. We hypothesize that it is easier to partake of economic, civic-political and social life in a new country for a person stemming from a culture that embodies tolerance towards people who are different. We test this by applying the epidemiological method, using a tolerance index based on two indicators fro

Digitalization: A Potential Tool for Sustainable Consumption?

Given the outsized impact that digitalization has had on consumption over the last two decades, the lack of academic interest in sustainable consumption is noteworthy. In this book chapter, we set the scene for the fundamentally important discussion about how digitalization affects consumption. We ask whether digitalization is a positive or a negative force for shaping consumption levels and patte

Using imlifidase to elucidate the characteristics and importance of anti-GBM antibodies produced after start of treatment

BACKGROUND: Autoantibodies are common in glomerulonephritis, but the clinical benefit of rapid elimination is not determined, even in anti-glomerular basement membrane (GBM) disease. Even less is known about the importance of autoantibody characteristics, including epitope specificity and IgG subclass distribution. By utilizing samples from the GOOD-IDES-01 trial, where imlifidase, cleaving all Ig

7T magnetic resonance angiographic imaging of basilar artery perforator aneurysms – initial experience of a non-invasive alternative to DSA

Background: Perforator aneurysms of the basilar artery (PABA) are rare causes of subarachnoid haemorrhage (SAH) and challenging to diagnose. We present two cases of SAH caused by PABA diagnosed by cone beam computed tomography angiography (CBCTA) and a novel non-invasive method – 7T magnetic resonance imaging (7T MRI). Methods: Two patients with SAH, diagnosed with PABA, were imaged on day 9 and 1

Defending the islands, defending the self: Taiwan, sovereignty and the origin of the Diaoyu/Senkaku Islands dispute as ontological security-seeking

The dispute over the Diaoyu/Senkaku Islands is generally analysed as a Sino-Japanese competition over material and strategic interests, regional preponderance, and nationalistic symbolism. Yet, such explanations cannot fully explain the endurance of the conflict and overlook its origin in the period leading up to the UN’s derecognition of Taiwan’s sovereignty in 1971. Drawing on the concept of ont