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Unpigmented skin cancer is the most prevalent form of cancer, and it burdens healthcare substantially even if it is not as aggressive as the more well-known malignant melanoma. Dermatoscopy images are commonly used for diagnosis, but differentiating between the many sub-diagnoses is a hard task. In this study we focus on these unpigmented cancers, performing both detection of basal cell carcinoma
BACKGROUND AND AIMS: Adhering to the EAT-Lancet diet has been observed to be associated with lower risks of various morbidities. This study aimed to investigate the association of adhering to the EAT-Lancet diet with incident chronic obstructive pulmonary disease (COPD) and identify plasma proteins mediating such association.METHODS: This prospective study involved 202 340 participants free of COP
Background: The burden of non-motor symptoms in Parkinson's disease (PD) can be measured with the Non-Motor Symptoms Scale (NMSS) and the International Parkinson and Movement Disorder Society Non-Motor Rating Scale (MDS-NMS), for which scoring systems, structure and clinical coverage differ. Objectives: The goal was to develop conversion formulas between the NMSS and the MDS-NMS scores. Methods: D
The monocarboxylate transporter (MCT) membrane protein family has 14 human members that perform key cellular functions, such as regulating metabolism. MCT8 and MCT10 have unique cargo specificity, transporting thyroid hormone and, in the case of MCT10, aromatic amino acids. Dysfunctional MCT8 causes the severe Allan-Herndon-Dudley syndrome, yet the (patho)physiology and function of MCT8 and MCT10
Introduction: Tumor deposits are an important negative prognostic factor for long-term oncological outcomes in colorectal cancer patients, independent of lymph node status. Several novel models have been proposed to further integrate tumor deposits into the TNM-staging system, but their comparative performance remains unclear. The aim of this study was to identify, compare and validate novel progn
Based on in-depth interviews with young people experiencing over-indebtedness in Sweden, the paper illustrates the social consequences of over-indebtedness among young adults, particularly in terms of how debt problems affect the entry into adulthood. Combining theories of the indebted subject, social exclusion, emerging adulthood and liminality, the analysis shows that over-indebted young subjectBased on in-depth interviews with young people experiencing over-indebtedness in Sweden, the paper illustrates the social consequences of over-indebtedness among young adults, particularly in terms of how debt problems affect the entry into adulthood. Combining theories of the indebted subject, social exclusion, emerging adulthood and liminality, the analysis shows that over-indebted young subject
A core principle of the Safe System approach is shared responsibility among stakeholders and road users. Traditionally, public actors have shouldered most of the stakeholder responsibility, and traffic safety has mainly been viewed as a duty of governments [1,2]. However, the United Nations and the World Health Organisation call on all stakeholders, both public and private, to take on the responsi
Traffic accidents pose a significant global challenge, causing nearly 1.2 million fatalities annually (WHO 2023). This alarming statistic places traffic accidents among the leading causes of death worldwide. In most countries, the police are responsible for compiling official accident statistics. They collect data at the scene of the accident, including details about the vehicles involved, the cir
As indicated in several earlier chapters in this anthology, traffic safety data are of many different types and studied in a large number of different activities. Many professional studies make use of already existing data, such as accident data records from police, insurance companies and hospitals, as well as statistical data derived from such databases. Other data are collected for specific pur
Background: In a previous study, we explored real-world programmed death-ligand 1 (PD-L1) testing and treatment patterns for patients with advanced non-small cell lung cancer (NSCLC) in the era of immune-oncology. The present study aimed to investigate overall survival (OS) with PD-(L)1 inhibitors with longer-term follow-up in the Swedish setting. Materials and methods: Data were extracted from th
Introduction: Comorbidities and public health conditions in haemophilia are receiving increasing attention. Aim: To analyse the prevalence of comorbidities and mortality in people with haemophilia (PwH) compared to matched controls in subgroups (factor consumption and sex). Methods: This study used longitudinal individual-level data (11 years) from national registers in three Nordic countries (Den
Youth anxiety disorders are common and heterogeneous. The Pediatric Anxiety Rating Scale (PARS) is a clinician-administered tool designed to assess overall anxiety severity, independent of specific symptoms. The thresholds on PARS for the reliable change index (RCI), the minimal clinically important difference (MCID), treatment response, and full and partial remission remain unclear. Using the Cli
This study shows that Leiopus taeniatus (Gmelin, 1790) (Coleoptera, Cerambycidae) is not a junior subjective synonym of Leiopus nebulosus (Linnaeus, 1758) but a senior subjective synonym of Leiopus punctulatus (Paykull, 1800), as revealed by Ivan I. Lepyokhin’s (Lepechin’s) original diagnosis and illustration of an unnamed “Cerambyx” beetle in his 1768–1772 expedition itinerary, subsequently adopt
Purpose: To assess implementation of an electronic patient reported outcomes platform, Recovery Tracker, which characterizes short term recovery following radical orchiectomy in patients with testicular cancer. Methods: Recovery Tracker was assigned based on procedure codes to patients undergoing radical orchiectomy at our institution. Patients were surveyed daily for the 10-day postoperative peri
