Prostate cancer is a heterogeneous disease for which the molecular mechanisms are still not fully elucidated. Prostate cancer research has traditionally focused on genomic and epigenetic alterations affecting the proteome, but over the last decade non-coding RNAs, especially microRNAs, have been recognized to play a key role in prostate cancer progression. A considerable number of individual micro

Background: The K3326X variant in BRCA2 (BRCA2∗c.9976A>T p.Lys3326∗rs11571833) has been found to be associated with small increased risks of breast cancer. However, it is not clear to what extent linkage disequilibrium with fully pathogenic mutations might account for this association. There is scant information about the effect of K3326X in other hormonerelated cancers. Methods: Using weighted lo

Essay published in Inchiesta about the emerging discipline of street art studies.

The Radon transform and its adjoint, the back-projection operator, can both be expressed as convolutions in log-polar coordinates. Hence, fast algorithms for the application of these operators can be constructed by using FFT, if data is resampled at log-polar coordinates. Radon data is typically measured on an equally spaced grid in polar coordinates, and reconstructions are represented (as images

This paper reviews the growing literature on “state capacity” in political science and related disciplines and proposes a new conceptualization of state capacity. The paper argues that most existing definitions and theories of state capacity are too closely tailored to explaining a particular set of outcomes – such as economic growth – which limits the applicability of the concept of state capacit

Relying on three new indicators of the information capacity of states, this paper provides new evidence on the ability of states to collect and process information about the territories and populations that they govern. The three indicators are (a) the availability of a reliable census, (b) the establishment of a permanent government agency tasked with processing statistical information about the

Since the German reform of asylum law in 1993, statistics indicate a significant decrease of protection claims and an increasing number of deportations. This article presents relevant domestic legislation and international agreements contributing to this development It focuses on how domestic and international law interact to inhibit or end the presence of protection seekers on German territory. I

The main objective of this paper is to challenge the treatment of first-person epistemic and evidential complement-taking predicates (CTPs) in Martin and White’s (2005) APPRAISAL theory, and to offer suggestions for improving the model. Based on the combined results of a corpus-based analysis of CTPs and of a psycholinguistic experiment, we demonstrate that several co-textual and situational facto

Recension av Peter Edelbergs doktorsavhandling.Review of Peter Edelbergs Ph.D. dissertation.

On the way to parenthood - (re)productions of gender, ethnicity, race and class in midwife consultations.The premise of this article is that subject positions, which parents-to-be hold during pregnancy, influence their future parenthood. The article examines how such subject positions are produced in midwife consultations. It shows how the man in a heterosexual couple is positioned as peripheral w

Global climate change is a major threat to biodiversity. Large-scale analyses have generally focused on the impacts of climate change on the geographic ranges of species and on phenology, the timing of ecological phenomena. We used long-term monitoring of the abundance of breeding birds across Europe and the United States to produce, for both regions, composite population indices for two groups of

We present the WD2014 chronology for the upper part (0-2850 m; 31.2 ka BP) of the West Antarctic Ice Sheet (WAIS) Divide (WD) ice core. The chronology is based on counting of annual layers observed in the chemical, dust and electrical conductivity records. These layers are caused by seasonal changes in the source, transport, and deposition of aerosols. The measurements were interpreted manually an

Special journal edition on "New Wave in Swedish Cinema".

Specialnummer om brittisk film.

We have previously reported that the xyloside 2-(6-hydroxynaphthyl) β-D-xylopyranoside (XylNapOH), in contrast to 2-naphthyl β-D-xylopyranoside (XylNap), specifically reduces tumor growth both in vitro and in vivo. Although there are indications that this could be mediated by the xyloside-primed glycosaminoglycans (GAGs) and that these differ in composition depending on xyloside and cell type, det

This essay suggests that the conceptualization of strategic communication as a field uniting several disciplines was an important step forward, but progress in absolute terms has been disappointing so far. Individual researchers open up new avenues of exploration and regularly arrive at answers to questions internally consistent with their respective perspectives. But the body of reasonably verifi