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Plasma VEGF-D and sFLT-1 are potential biomarkers of hemodynamics and congestion in heart failure and following heart transplantation

BackgroundInflammation and tyrosine-kinases are known mediators in the pathobiology of cardiovascular disease. Plasma biomarkers reflecting these systems may provide a noninvasive complement reflecting hemodynamics, aiding in clinical decision-making. We therefore aimed to investigate the plasma levels of vascular and inflammatory proteins, and their associations with invasive hemodynamics in adva

Consuming Seaweeds: In The Laboratory And Beyond

Based on fieldwork in a sensory science laboratory in Sweden, this paper brings the social aspects of conducting an analytical sensory panel together with consumers’ understandings of the everyday consumption context and existing practices. As part of an interdisciplinary project investigating seaweed as a new food in a Swedish context, this paper explores how seaweed as a new resource is made edi

Unveiling the Supply Chain Digital Transformation of Small and Medium Enterprises

The global shift to a knowledge-based economy is driven by rapid advancements in information and communication technology (ICT). Within this landscape, digital transformation of supply chains is crucial for enterprises, particularly small and medium-sized businesses (SMEs), seeking to boost performance and efficiency in competitive markets. Despite increased awareness of this importance, there is

Mapping of friction, wear and particle emissions from high-speed train brakes

This study reports contact pressure-sliding speed maps for friction, wear and particle emissions from high-speed train brakes. Two particle spectrometers measured the airborne wear particles generated with a pin-on-disc tribometer. Particles were characterized with transmission electron microscopy and energy dispersive X-ray fluorescence. The results indicate that both the friction and wear of bra

Transition from Schizotypal Disorder to Non-Affective Psychotic Disorders Including Schizophrenia: A Nationwide Swedish Cohort Study

This study evaluated the transition rates from schizotypal disorder to non-affective psychosis and schizophrenia in particular aiming to identify clinical and demographic factors associated with these transitions. We conducted a nationwide cohort study using data from the Swedish Patient Register and the Cause of Death Register, including patients aged 18 and older diagnosed with schizotypal disor

Exploring digital health : a qualitative study on adults’ experiences with health apps and wearables

Purpose: From an active ageing perspective, investigating how adults use apps and wearables for health purposes might improve well-being strategies supported by widely adopted technologies. This study investigated adults’ perceptions of using apps and wearables for health purposes. Methods: A qualitative interview study was conducted. Adults (+18) using an app/wearable to monitor at least one heal

World Stroke Organization : Global Stroke Fact Sheet 2025

Background: Among non-communicable disorders (NCDs), stroke remains the second leading cause of death and the third leading cause of death and disability combined (as expressed by disability-adjusted life-years lost—DALYs) in the world. Aims: The study was aimed to estimate global, regional and nationa burden of stroke and its risk factors from 1990 to 2021. Methods: Finding presented in this pape

Uniformity of refugee status in EU law and secondary movements: insights from QY v Germany and A., v Generalstaatsanwaltschaft Hamm

In QY v Bundesrepublik Deutschland (Effect of a decision granting refugee status) the Court of Justice held that Member State are not required under EU to automatically recognize the positive decision issued by another Member State. Such a positive decision does have some significance, but very far from being anything close to automatically binding as to the positive conclusion that the applicant

Human antimicrobial/host defense peptide LL-37 may prevent the spread of a local infection through multiple mechanisms : an update

BACKGROUND: Human cathelicidin LL-37 shows activity towards both gram-positive and gram-negative bacteria, and it is also active against some types of viruses. Besides its antimicrobial effects, the peptide modulates innate immunity through binding and inactivation of bacterial endotoxins and promoting chemotaxis of immune cells.RESULTS: LL-37 is reported to interact with plasma membrane receptors

Extending the Lund-Malmö creatinine-based GFR equation to cystatin C–validation results from the European Kidney Function Consortium (EKFC) cohort of children and adults

The aim of the present study was to extend the creatinine-based Lund-Malmö GFR equation for use with rescaled cystatin C (r-LMRCys) and validate it against measured GFR (mGFR) in the EKFC cystatin C cohort of children (n = 2,293) and adults (n = 7,727). Rescaling was obtained by dividing each biomarker by a Q-value, representing the population-specific median biomarker level among healthy individu

Impact of TCF7L2 rs7903146 on clinical presentation and risk of complications in patients with type 2 diabetes

Aims: TCF7L2 rs7903146 is the most impactful single genetic risk variant for type 2 diabetes. However, its role on disease progression, complications and mortality among people with type 2 diabetes at diagnosis remains unclear. Materials and Methods: We assessed the per allele impact of the rs7903146 T-allele on clinical characteristics and complication risk in 9231 individuals with type 2 diabete

Lipid-induced condensate formation from the Alzheimer’s Aβ peptide triggers amyloid aggregation

The onset and development of Alzheimer’s disease is linked to the accumulation of pathological aggregates formed from the normally monomeric amyloid-β peptide within the central nervous system. These Aβ aggregates are increasingly successfully targeted with clinical therapies at later stages of the disease, but the fundamental molecular steps in early stage disease that trigger the initial nucleat

Bystander Intervention Programs Focusing on Sexual Violence in Academia—A Scoping Review

Sexual violence within academia is a major concern, and increased attention is being given to bystander interventions to combat these behaviors. This scoping review aimed to investigate bystander intervention programs focused on the prevention of sexual violence in universities worldwide. Literature searches were conducted using ERC, ERIC, Web of Science, PsycInfo, and PubMed databases. The inclus

Negotiating for influence and resources : A study of Swedish teachers’ and principals’ experiences of aggressive emails from parents

This article focuses on teachers’ and principals’ experiences of aggressive emails in home–school collaborations with parents. Semi-structured interviews with 31 teachers and principals from primary, lower and upper secondary schools in Sweden were conducted. Three categories were identified in the material which illuminate the phenomenon of cyberaggression towards principals and teachers from par

Study on the Influence of External Electric Field Control and Vibrational Quantum Effect on the Charge Separation Mechanism in Fullerene-Based Systems

Based on the DCV-C60 system of fullerene acceptor organic solar cell active materials, the charge transfer process of D-A type molecular materials under the action of an external electric field (Fext) was explored. Within the range of electric field application, the excited state characteristics exhibit certain regular changes. Based on reducing the excitation energy, the excitation mode shows a t

Work-related cyber mistreatment from guardians, members of the public, and pupils in the context of educational work – From incivility to aggression

This study explores the nature of work-related cyber mistreatment from guardians, pupils, and members of the public as experienced by educational workers. Thematic analysis of data collected by semi-structured interviews with 31 teachers and principals resulted in two overarching themes; directly addressed cyber mistreatment in email and unwanted negative exposure on social media. The data spans o