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Development and prevention of ischemic contracture (“stone heart”) in the pig heart

Stone heart (ischemic contracture) is a rare and serious condition observed in the heart after periods of warm ischemia. The underlying mechanisms are largely unknown and treatment options are lacking. In view of the possibilities for cardiac donation after circulatory death (DCD), introducing risks for ischemic damage, we have investigated stone heart in pigs. Following cessation of ventilation,

Sustainability and semantic diversity : A view from the Malayan rainforest

Sustainable development goals assume that basic notions such as health, life and water can be universally and easily expressed and understood across diverse communities and stakeholders. Yet there is growing evidence pointing to considerable semantic diversity in how humans represent the world in language. In this paper I discuss such semantic diversity in the context of key notions of sustainabil

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Chromothripsis is a mutational phenomenon characterized by massive, clustered genomic rearrangements that occurs in cancer and other diseases. Recent studies in selected cancer types have suggested that chromothripsis may be more common than initially inferred from low-resolution copy-number data. Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Can

Recurrence and transience of Rademacher series

We introduce the notion of a-walk S(n) = a1X1 +… + anXn, based on a sequence of positive numbers a = (a1, a2,…) and a Rademacher sequence X1,X2,…. We study recurrence/ transience (properly defined) of such walks for various sequences of a.

Heterotopic mineral deposits in intact rat Achilles tendons are characterized by a unique fiber-like structure

Heterotopic mineralization entails pathological mineral formation inside soft tissues. In human tendons mineralization is often associated with tendinopathies, tendon weakness and pain. In Achilles tendons, mineralization is considered to occur through heterotopic ossification (HO) primarily in response to tendon pathologies. However, refined details regarding HO deposition and microstructure are

Secure Software Updates for IoT Based on Industry Requirements

This paper analyzes the problem and requirements of securely distributing software updates over the Internet,to devices in an Industrial Control System (ICS) and more generally in Internet of Things (IoT) infrastructurescontrolling a physical system, such as power grids and water supply systems. We present a novel approachthat allows to securely distribute software updates of different types, e.g.

Teaching Process Improvement and Hitting All Key Criteria for a Modern University Course

While process improvement is an increasingly important topic for organizations, academic institutions find it hard to teach the topic in a cross functional real world project manner. This paper describes a unique course which is theoretically sound, academically rigorous, multi-disciplinary, and practically relevant while providing the students with a transformational learning opportunity. The cou

Obesity and the risk of cardiometabolic diseases

The prevalence of obesity has reached pandemic proportions, and now approximately 25% of adults in Westernized countries have obesity. Recognized as a major health concern, obesity is associated with multiple comorbidities, particularly cardiometabolic disorders. In this Review, we present obesity as an evolutionarily novel condition, summarize the epidemiological evidence on its detrimental cardi

Becoming Male Sex Worker, Doing Masculinities. Socio-Sexual Interactions and Gender Production in Men Selling Sex to Men in Italy and Sweden

Although masculinity is a powerful concept in both sociology and gender studies, previous research forgot to analyse sex work under this perspective. Even though the actors involved are men, and previous studies have highlighted the importance of masculinity not only in the relation manto- woman but also in the “gay world”, there is a lack of attention in male sex working. Then, the aim of this pa

Imaging-based assessment of fatty acid composition in human bone marrow adipose tissue at 7 T : Method comparison and in vivo feasibility

Purpose: To demonstrate the feasibility and accuracy of chemical shift–encoded imaging of the fatty acid composition (FAC) of human bone marrow adipose tissue at 7 T, and to determine suitable image-acquisition parameters using simulations. Methods: The noise performance of FAC estimation was investigated using simulations with a range of inter-echo time, and accuracy was assessed using a phantom

Straffbar exploatering i arbete? : Arbetet i restaurangen NJA 2022 s. 23

Införandet av människoexploateringsbrottet i 4 kap. 1 b § BrB aktualiserar ett antal frågor som tidigare inte behandlats i praxis. Bestämmelsen prövades för första gången av Högsta domstolen i NJA 2022 s. 23, vilket är det avgörande denna artikel kommenterar. Författaren visar att domstolen ställt upp en ordning för hur prövningen ska gå till, diskuterar innebörden av rekvisitet exploatering samt

Beyond Urban Sketching: Ethnographic Drawing as a Visual Analytical Method

starting point. Through active participation as an urban sketcher through digital publishing,dialogue and interaction, I analyze my analytical process and urban sketching practice. Theaim is to examine ethnographic drawing as a visual cultural analytical method. My contributionis based the connection between urban ideals and innovative, creative environments in alocal context. An overall knowledgeIn this article I have chosen a contemporary phenomenon, urban sketching, as an empirical starting point. Through active participation as an urban sketcher through digital publishing, dialogue and interaction, I analyze my analytical process and urban sketching practice. The aim is to examine ethnographic drawing as a visual cultural analytical method. My contribution is based the connection betwe

Learning insertion of a Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) catheter : Is clinical experience necessary? A prospective trial

Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an emerging and potentially life-saving procedure, necessitating qualified operators in an increasing number of centres. The procedure shares technical elements with other vascular access procedures using the Seldinger technique, which is mastered by doctors not only in endovascular specialties but also in trauma surg

Intensified role of the European Union? : European Research Infrastructure Consortium as a legal framework for contemporary multinational research collaboration

This chapter gives an introduction to the European Research Infrastructure Consortium (ERIC) – a European Union (EU) policy tool introduced in 2009 with the purpose to set up and operate collaborative Research Infrastructures by granting them a legal personality and qualities of an international organization. The shared responsibility between the member states and the EU in the research and innova

Heat dissipation from photosynthesis contributes to maize thermoregulation under suboptimal temperature conditions

The extent to which plants thermoregulate to maintain relatively stable metabolic function in response to gradual and rapid temperature changes that jeopardize crop production is unclear. Maize thermoregulation was investigated based on leaf temperature (TL) measurements and its relationship with photochemistry and stomatal conductance (gs) under dry and wet soil scenarios. Seasonal climatology wa