Popular Abstract in Swedish Celldöd är en lika viktig process som celldelning. Under hela ens liv måste vävnadens storlek regleras och gamla eller skadade celler förnyas. Detta styrs av en process som kallas programmerad cell död. Denna process är noggrant reglerad så att enbart oönskade celler tas bort. Om regleringen sätts ur funktion leder detta till ohämmad celldelning och cancer. Ett problem HAMLET (Human alpha-lactalbumin made lethal to tumor cells) is a molecular complex of alpha-lactalbumin and oleic acid, that induces programmed cells death in tumor cells but leaves healthy differentiated cells unaffected. It has a broad anti-tumor activity as more than 40 cell lines from different origin are sensitive. The cell death activity of HAMLET is retained in vivo. HAMLET limits the progr

This article gives an overview of some ethical problems raised in connection to nutritional genomics, especially the use of knowledge from nutrigenomics as a basis for personalised nutrition after a genetic test.

The aim of this controlled study was to evaluate a 1-year learner-centred educational project in end-of-life care for home care staff in a rural district of Sweden. Another rural district in the same region served as a control area. A 20-item questionnaire measuring attitudes towards end-of-life care was designed, and the Hospital Anxiety and Depression (HAD) scale was used to measure mental well

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Objective and Background. To evaluate risk factors for shoulder dystocia and brachial plexus injury using a case-control study at the departments of obstetrics and gynecology at the four largest hospitals in southern Sweden. All cases of shoulder dystocia between 1987 and 1993 inclusive were identified. For each case, two control infants with similar birthweight (+/- 100 g) and identical year of b

Popular Abstract in Swedish Syftet med denna avhandling är att analysera och förklara den institutionella förändringen vad gäller läkemedelsförsäljning i Sverige. Avhandlingens bidrag är studier av denna specifika institutionella utveckling där nyinstitutionell ekonomisk teori har använts för att undersöka drivkrafterna. Avhandlingen består av tre artiklar. Syftet med den första artikeln är att beThe aim of this thesis is to analyze and to explain the institutional change in the provision of pharmaceuticals in Sweden. The thesis’ contribution is studies of this specific institutional development. New Institutional Economic theory is used to scrutinize the driving forces of this development. The thesis consist of three papers. The purpose of the first paper is to discuss and to analyze the

Recent theoretical analysis suggests that a reduction in the cost of exporting increases the degree of assortative matching between workers and firms in export-oriented industries. Changes that reduce the cost of imports have an ambiguous impact on matching. We combine detailed Swedish matched worker-firm data from 1995 – 2005 with tariff data to test these hypotheses. The data cover 94 sectors su

The formation of various aluminides and intermetallic compounds in the Al-Ni-Ti ternary system offers great potential for a wide variety of applications. In the present work, reactions occurring during the heating of compacted ternary Al-Ni-Ti elemental powder mixtures were studied using differential scanning calorimetry (DSC). The effect of composition on the reaction behavior was studied by vary

Phage display technology has emerged as a leading approach to select proteins with improved properties for many different types of applications. The selection typically selects not only for improved binding properties but also for other factors such as efficiency of protein production and folding in Escherichia coli, the host in which the proteins and the phage are produced. Furthermore, the selec

The streaming instability is a promising mechanism to overcome the barriers in direct dust growth and lead to the formation of planetesimals. Most previous studies of the streaming instability, however, were focused on a local region of a protoplanetary disk with a limited simulation domain such that only one filamentary concentration of solids has been observed. The characteristic separation betw

Hassles and uplifts, a concept used in measuring daily stress events, was applied to working mothers' everyday life. The aim was to explore the stability in working mothers' experiences in patterns of daily occupations, operationalized as hassles and uplifts, between the year 2000 (baseline) and the year 2005 (follow-up). Further, the intention was to reveal possible differences in the number, ori

A short and efficient total synthesis of rac-desoxygaliellalactone and (+)-desoxygaliellalactone, via the biosynthetic intermediate pregaliellalactone, is described. The synthesis was achieved in only three steps, for (+)-desoxygaliellalactone including an enantioselective alkyl propiolate addition to 4-pentenal, a palladium catalysed alkylative lactonisation and an intramolecular Diels-Alder cycl

Popular Abstract in Swedish Den här avhandlingen innehåller fyra uppsatser som på ett eller annat sätt relaterar till befolkningsströmningar såsom dess ekonomiska konsekvenser och orsaker. I den första uppsatsen används en hushållsundersökning från Kina för att undersöka huruvida utbildning bidrar till att höja inkomsterna hos hushåll i jordbrukssektorn. Genom regressionsanalys uppmäts korrelatioAbstract Population movements are more substantial today than at any other point in human history. If managed effectively, migration can be beneficial for all aspects of social and economic life. This thesis contains four papers, all of which are related to the economic consequences and determinants of migration, within and across countries. The first paper employs a household survey to explore

Novel magneto-resistive memory effect is demonstrated, which appears in lithographically patterned Y-shaped, three-terminal nanostructures, consisting of three nanowires joined in one point, formed in the epitaxial layer of a ferromagnetic (Ga, Mn) As semiconductor. The effect, in which the zero-field resistance of a pair of nanowires depends on the direction of the previously applied magnetic fie

The distinction between the agent-relative and the agent-neutral plays a prominent role in recent attempts to taxonomize normative theories. Its importance extends to most areas in practical philosophy, though. Despite its popularity, the distinction remains difficult to get a good grip on. In part this has to do with the fact that there is no consensus concerning the sort of objects to which we s

In this study the cutting tool temperature that develops during rough turning of hardened cold-work tool steel is modelled on the basis of experimental data. The data obtained from a series of thermocouples, placed on a PCBN insert, into an anvil, and into a toolholder, were used as the input for the model. An inverse problem was solved, where the heat fluxes and heat transfer coefficients were co

Using a new concept—the law of the limit to land productivity—this article builds a three (physical, economic, and institutional) worlds’ land-use model with inverse logics of different development stages in a time perspective: before, in, and after the population trap. This model extends the span of the Malthusian population model to history after the Industrial Revolution and makes static proper

We performed a detailed study of the ratio of low-alpha to high-alpha stars in the Galactic halo as observed by the Gaia-ESO Survey. Using a sample of 381 metal-poor stars from the second internal data release, we found that the value of this ratio did not show evidence of systematic trends as a function of metallicity, surface gravity, Galactic latitude, Galactic longitude, height above the Galac