Glypican-1 is a glycosylphosphatidylinositol anchored cell surface S-nitrosylated heparan sulfate proteoglycan that is processed by nitric oxide dependent degradation of its side chains. Cell surface-bound glypican-1 becomes internalized and recycles via endosomes, where the heparan sulphate chains undergo nitric oxide and copper dependent autocleavage at N-unsubstituted glucosamines, back to the

Deletion of the tumor suppressor gene p53 has been shown to improve the outcome in experimental models of focal cerebral ischemia and kainate-induced seizures. To evaluate the potential role of p53 in traumatic brain injury, genetically modified mice lacking a functional p53 gene (p53(-/-), n = 9) and their wild-type littermates (p53(+/+), n = 9) were anesthetized and subjected to controlled corti

With more advanced manufacturing technologies, small and medium sized enterprises can compete with low-wage labor by providing customized and high quality products. For small production series, robotic systems can provide a cost-effective solution. However, for robots to be able to perform on par with human workers in manufacturing industries, they have to become flexible and autonomous in their t

Results of epidemiological studies have suggested that consumption of green tea could lower the risk of type 2 diabetes. Intervention studies show that green tea may decrease blood glucose levels, and also increase satiety. This study was conducted to examine the postprandial effects of green tea on glucose levels, glycemic index, insulin levels and satiety in healthy individuals after the consump

OBJECTIVES: The aim of this study was to determine if there were any long-lasting elevated anxiety levels in women attending colposcopy after an abnormal cervical smear. DESIGN: Prospective study. SETTING: Department of Obstetrics and Gynaecology, Malmö University Hospital, Sweden. POPULATION: One hundred consecutive women were invited to participate when referred for colposcopy. METHODS: Women in

Magnetic resonance spectroscopy (MRS) is a non-invasive technique that can be used to detect and quantify multiple metabolites. This chapter will review some of the applications of MRS to the study of brain functions. Typically, (1)H-MRS can detect metabolites reflecting neuronal density and integrity, markers of energy metabolism or inflammation, as well as neurotransmitters. The complexity of th

To compare work-loss in RA patients starting their first biologic with high vs moderate disease activity.

We report on lifetime measurements of the 3d(5)(S-6)4s4p(P-3)y P-6 degrees states of Fe II using time-resolved vacuum ultraviolet (VUV) laser spectroscopy. A laser-produced plasma has been used as the source of free Fe+ ions. The tunable VUV radiation was obtained employing resonantly enhanced sum-difference four-wave-mixing of short laser pulses. We obtained tau((6)P(3/2)degrees) = 3.90(20) ns, t

Popular Abstract in Swedish Nuförtiden är det tryckta bokomslaget en självklar del av boken som produkt och konsumentvara. I avhandlingen studeras etableringen av bokomslaget och dess betydelse för omstruktureringen av bokmarknaden i Sverige decennierna kring 1800. Från mitten av 1700-talet blev den färdigbundna boken en betydelsefull del av bokhandelns utbud. Förlag och bokhandel började sälja deThe aim of the dissertation is to examine the significance of the paperbound book on the book market as part of the history of consumption. It is an examination of the materiality of the book, in which the form and function, economics and distribution of the binding during the last century of the hand-press era are studied. The intention has been to show that the ready-bound book was a means for t