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Peripheral versus central extracorporeal membrane oxygenation for postcardiotomy shock : Multicenter registry, systematic review, and meta-analysis

Background: We hypothesized that cannulation strategy in venoarterial extracorporeal membrane oxygenation (VA-ECMO) could play a crucial role in the perioperative survival of patients affected by postcardiotomy shock. Methods: Between January 2010 and March 2018, 781 adult patients receiving VA-ECMO for postcardiotomy shock at 19 cardiac surgical centers were retrieved from the Postcardiotomy Veno

Profiles of bystanders' motivation to defend school bully victims from a self-determination perspective

This study was aimed at exploring which latent profiles emerge based on ratings of self-determined motivation to defend victims of bullying, and to explore if they are related to bystander roles and victimization in bullying, as well as student–teacher relations. Data were collected from 1,800 Swedish and Italian students, with an age range between 10 and 18 years (M = 12.6, standard deviation = 1

Psychological readiness is related to return to sport following hip arthroscopy and can be assessed by the Hip-Return to Sport after Injury scale (Hip-RSI)

PURPOSE: Psychological readiness may play an important role in the return to sport (RTS) process following hip arthroscopy (HA), but there are limited tools for the measurement of this construct. The aim of this study was to modify the Swedish version of the Anterior Cruciate Ligament-Return to Sport after Injury (ACL-RSI) scale for use in HA patients and evaluate its psychometric properties.METHO

Experimental optimization of X-ray propagation-based phase contrast imaging geometry

Propagation-based phase contrast imaging (PB-PCI) with an X-ray lab source is a powerful technique to study low absorption samples, e.g. soft tissue or plastics, on the micrometer scale but is often limited by the low flux and coherence of the source. The setup geometry is essential for the performance since there is a trade-off where a short source distance yields a high contrast-to-noise ratio (

The transfer of clinical prediction models for early trauma care had uncertain effects on mistriage

Objectives: This study aimed to assess how transfers of clinical prediction models for early trauma care between different care contexts within a single health system affected mistriage rates. Study Design and Setting: Patients aged 15 years or older, registered between 2011 and 2016 in the Swedish national trauma registry, SweTrau, were included. Three data set groups were created: high- and low-

NOMI after cardiac arrest. Could refined diagnostics improve outcome?

Intestinal ischaemia is usually classified into acute mesenteric ischaemia (AMI), chronic mesenteric ischaemia and colonic ischaemia. Coeliac, inferior and superior mesenteric arterial/venous emboli/thrombi and non-occlusive mesenteric ischaemia (NOMI) can cause AMI. NOMI pathophysiology involves hypoperfusion, aggravated by bacterial translocation, reperfusion injury, apoptosis and decreased prol

Evaluation of a miniaturized thermal biosensor for the determination of glucose in whole blood

A miniaturized thermal biosensor has been evaluated as part of a flow-injection analysis system for the determination of glucose in whole blood. Glucose was determined by measuring the heat evolved when samples containing glucose passed through a small column with immobilized glucose oxidase and catalase. Samples of whole blood (1 μl) can be measured directly, without any pretreatment. The correla

Time-Resolved Grazing Incidence X-Ray Absorption Spectroscopy for the In Situ Investigation of the Initial Stages of Sputter-Deposited Copper Thin Films

The sputter deposition and the growth of thin copper films on float glass substrates are in situ studied using grazing incidence, reflection mode X-ray absorption fine structure spectroscopy with subsecond time resolution. The experimental data are compared with model calculations, assuming the presence of crystalline, face-centered cubic metallic Cu nanostructures. From a detailed analysis of the

HC-IgA antibodies of different specificities are normally present in serum : quantitation by ELISA and relationship to the major Ig classes

Enzyme-linked immunosorbent assays (ELISA) were developed for direct measurement of protein HC-IgA complexes (HC-IgA) in serum with antibody specificity for rabbit IgG (rheumatoid factor (RF) activity), lipopolysaccharide from Yersinia enterocolitica serotype O:3 (Y3) and tetanus toxoid (TT). About 80% of patients with rheumatoid arthritis had increased concentrations of HC-IgA-RF. The values were

Recent investigations on calorimetric biosensors

New applications of a flow-calorimetric biosensor system, the enzyme thermistor (ET) are described. The ET measures the reaction heat in a small column containing immobilized biocatalyst as a temperature change of the effluent from the column. Since most biological reactions are exothermic, the ET has a very broad applicability and numerous assays of clinical as well as biotechnological interest h

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A method of manufacturing a protein chip for identifying aminoacyl-tRNA synthetases, suitable for detecting basic amino acids in proteins. It is characterized in, immoblizing aminoacyl-tRNA synthetases corresponding to 20 basic amino acids in arrays onto the surface of the chip, then fixing 20 kinds of tRNAs labelled by fluorescence onto the corresponding synthetases, then obtaining a chip of amin

Diagnostic value of analysis of cystatin C and protein HC in biological fluids

Cystatin C, a 13 kDa-protein, is produced by most nucleated cells and is catabolized by the renal tubular cells after passing the glomerular filter. It belongs to the family 2 of the cystatin superfamily of proteins. The function of cystatin C is to regulate the activity of cysteine proteinases and cystatin C seems to be the main cysteine proteinase inhibitor of most investigated human biological

A rapid enzyme-linked immunosorbent assay for serum amyloid A using sequence-specific antibodies

A microtitre plate based enzyme-linked immunosorbent assay for determining the concentration of serum amyloid A (SAA) is described. The method employs easily produced sequence-specific rabbit antibodies and the preferential absorption of SAA to polystyrene, which obviates the use of capture antibodies and allows an assay time of only 3.5 h, so that the diagnostic potential of the SAA level as a ra

The influence of different scattering algorithms on room acoustic simulations in rectangular rooms

Raytracing is a widespread tool for room acoustic simulations, and one of its main advan-tages is the inclusion of surface scattering. Although surface scattering has been acknowledged as a central aspect of accurate raytracing simulations for many years, there is ongoing research into its effects and how to implement it better. This study evaluates three different algorithms for surface scatterin

Symmetric shift-invariant subspaces and harmonic maps

The Grassmannian model represents harmonic maps from Riemann surfaces by families of shift-invariant subspaces of a Hilbert space. We impose a natural symmetry condition on the shift-invariant subspaces that corresponds to considering an important class of harmonic maps into symmetric and k-symmetric spaces. Using an appropriate description of such symmetric shift-invariant subspaces we obtain new

Cross-country differences in preferences for leisure

The starting point of this paper is to document considerable cross-country variation in the “labor wedge”, a common measure of labor market frictions. Its variation is theoretically isomorphic to differences in a preference-for-leisure parameter. The paper proceeds to investigate what might explain the variation. It presents three separate empirical exercises supportive of the view that, to a subs

Nontypeable haemophilus influenzae P5 binds human C4b-binding protein, promoting serum resistance

Nontypeable Haemophilus influenzae (NTHi) is a Gram-negative human pathogen that causes infections mainly in the upper and lower respiratory tract. The bacterium is associated with bronchitis and exacerbations in patients suffering from chronic obstructive pulmonary disease and frequently causes acute otitis media in preschool children. We have previously demonstrated that the binding of C4b bindi

Bayesian Optimization with a Prior for the Optimum

While Bayesian Optimization (BO) is a very popular method for optimizing expensive black-box functions, it fails to leverage the experience of domain experts. This causes BO to waste function evaluations on bad design choices (e.g., machine learning hyperparameters) that the expert already knows to work poorly. To address this issue, we introduce Bayesian Optimization with a Prior for the Optimum