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Blood pharmacokinetics of various mabs labeled with a new tri-chelating reagent for simultaneous conjugation with DOTA and biotin prior to radiolabeling
Quality of life in older people receiving ADL help: Help, help providers, and complaints.
Popular Abstract in Swedish Äldre personer som erhåller permanent hjälp i sitt dagliga liv har ökat i takt med att livslängden ökat. Många äldre personer kommer troligen framöver att erhålla hjälp i sitt ordinära boende, eftersom den kommunala vården och omsorgen framför allt inom särskilt boende har minskat i omfattning i förhållande till antalet äldre över 65 år. Svensk policy strävar mot att alThe aim of this thesis was to investigate self-reported diseases and complaints, quality of life (QoL), help received with activities of daily living among older people and in relation to who provided the help, and in comparison with those without ADL help. The aim was also to investigate older people’s experiences of receiving help. Data were collected using postal questionnaires in two populatio
Spatial variation and patterns of soil microbial community structure in a mixed spruce-birch stand
To explore the spatial variation of the soil microbial community within a mixed Norway spruce-birch stand, and to test if the spatial patterns of the microbial community are related to the position of trees, we sampled the forest floor at two spatial scales and used the phospholipid fatty acid (PLFA) patterns as indicators of the microbial community structure. Of the 32 most common PLFAs, 20 (62%)
Pia Köhlmyr. "To Err is Human ...": An investigation of grammatical errors in Swedish 16-year-old learners' written production in English
Predominance of CIN versus MSI in the development of rectal cancer at young age.
BACKGROUND: Development of proximal and distal colorectal cancers involve partly different mechanisms associated with the microsatellite instability (MSI) and the chromosomal instability (CIN) pathways. Colorectal cancers in patients under 50 years of age represent about 5% of the total number of tumors and have been associated with an increased frequency of MSI tumors. However, MSI and CIN may pl
Structure and magnetism on in situ ultrathin epitaxial films: XMCD and EXAFS on Fe/Ag(100)
We have made in situ investigations of epitaxial ultrathin Fe films on Ag(100). This system is known to exhibit a reorientation of the magnetization, dependent of Fe thickness and temperature. Our aim here is to correlate the local structure with the magnetic properties of this system. The X-ray absorption fine structure has been recorded in situ both in the near edge as well as in the extended X-
Bacterial destruction of mica during bioleaching of kaolin and quartz sand by Bacillus cereus
Growth and metabolic activities of Bacillus cereus were found to cause the extraction of iron atoms from the octahedral position in mica in the kaolin sample (49%) and in the quartz sands sample (17%) after 3 months of bioleaching, while aluminium removal was only 5%. Mica destruction was detected in kaolin and quartz sands samples by X-ray diffraction analysis and also by i.r. adsorption spectros
Endovascular healing is inadequate for fixation of Dacron stent-grafts in human aortoiliac vessels
BACKGROUND: migration and kinking of stent-grafts can occur late after endovascular aneurysm repair. It is unknown if endovascular grafts incorporate enough to be permanently anchored. In this report, healing of aortic stent-grafts was assessed in humans. PATIENTS AND METHODS: we retrieved 23 Dacron stent-grafts from patients treated for an aortic aneurysm since 1993. Twelve stent-grafts were expl
Water contamination effects of the lubricant on the hydrogen absorbing tendency of deep groove ball bearings
One-way wave operators for nonstationary dielectrics
Propagation of transverse electric and magnetic (TEM) pulses in nonstationary, linear, homogeneous, and isotropic dielectric and magnetic materials is investigated using an exact wave splitting. Key intrinsic properties are the index of refraction and the relative admittance, which are both temporal integral operators with kernels that depend on two time variables. In addition, the Sommerfeld fore
Ekokardiografi förfinar diagnostiken vid hjärtsvikt
Eko-doppler med vävnadsdoppler ger säkrare hjärtsviktsdiagnostik och kan utföras vid sängkanten. Vävnadsdoppler har givit ny insikt i patofysiologin vid hjärtsvikt. Färgvävnadsdoppler är grunden för parametriska hjärtbilder och kan användas för icke-invasiv skattning av fyllnadstryck. Systolisk och diastolisk funktion är alltid kopplade. Man bör därför använda begreppen »svikt med normal EF« respe
Kylterapi efter hävt hjärtstopp tycks skydda hjärnan. Behandling bör ske enligt protokoll och behandlingsdata registreras
30 år av framgångsrik mykobakterieforskning. AHRI i Addis Abeba unik forskningsmiljö i u-land
The Armauer Hansen Research Institute (AHRI) in Addis Abeba, Ethiopia, was established by the Swedish and Norwegian Save the Children organisations in collaboration with the University of Bergen, with the principal objective of pursuing basic research in leprosy. The institute has a commendable record of achievement, and has made significant contributions to our understanding of leprosy and its co
Characterization of two distinct aryl hydrocarbon receptor (AhR2) genes in Atlantic salmon (Salmo salar) and evidence for multiple AhR2 gene lineages in salmonid fish
The aryl hydrocarbon receptor (AhR) mediates the toxicity of several environmental contaminants, e.g. 2,3,7,8-tetrachlorodibenzo-p-dioxin, and other halogenated hydrocarbons in vertebrates. This receptor initiates the transcription of several biotransformation enzymes, which in turn are responsible for causing severe harm to biological tissue. Here we describe the isolation and complete characteri
On-line diagnostic tool for measurement of the time delay between two ultrashort light pulses
Ultrafast accelerator-based sources combined with synchronized femtosecond lasers are currently being developed. The method described here is intended as a jitter monitor at such facilities. We report on the possibility of extracting a time-offset signal between two different synchronized ultrashort light pulses. The method is based on sum-frequency generation in a nonlinear crystal. Aiming at ext
Paleolitisk kost och evolutionsmedicin: nyckel till västvärldens sjukdomar
Development of lentiviral vectors for CNS gene transfer
Popular Abstract in Swedish Att leverera ett läkemedel till hjärnan är svårt då blod-hjärnbarriären effektivt stoppar de flesta kemiska substanser eller kräver att läkemedlet ges i höga systemiska doser. Om läkemedlet passerar blod-hjärnbärriaren påverkar det i så fall alla strukturer och celltyper. Detta är problematiskt i hjärnan då det här finns avgränsade strukturer med olika funktion, ibland Gene therapy in the brain is a promising treatment strategy that in the future may be used for several brain disorders, including Parkinson's disease, Alzheimer's disease and lysosomal storage diseases. By introducing a new gene, rather than providing a classical pharmacological drug, gene therapy offers the opportunity to treat neurological disorders by a single intervention. However, gene therap
Results of the first World Health Organization international collaborative study of detection of Human Papillomavirus DNA.
Twenty-nine laboratories in 12 countries participated in a study to assess the performance of various human papillomavirus (HPV) detection assays through the use of a recombinant HPV DNA standard reagent panel. The panel was designed by a group of HPV experts, and samples were prepared and distributed by the World Health Organization International Laboratory for Standards and Biologicals in The Ne
Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues
Using PCR with degenerate primers and screening of a human B-cell lymphoblast cDNA library, a full-length cDNA encoding a 375-amino-acid protein was isolated. It contains seven regions of hydrophobic amino acids probably representing membrane-spanning domains of a novel heptahelix receptor, tentatively named CMKRL2. It shows nearly 30% overall identity with the high-affinity IL8 receptor and simil