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How many individuals to use in a QA task with fixed total effort? - Defect detection as a function of time

Increasing the number of persons working on quality assurance (QA) tasks, e.g., reviews and testing, increases the number of defects detected – but it also increases the total effort unless effort is controlled with fixed effort budgets. Our research investigates how QA tasks should be configured regarding two parameters, i.e., time and number of people. We define an optimization problem to answer

Global observations of aerosol-cloud-precipitation-climate interactions

Cloud drop condensation nuclei (CCN) and ice nuclei (IN) particles determine to a large extent cloud microstructure and, consequently, cloud albedo and the dynamic response of clouds to aerosol-induced changes to precipitation. This can modify the reflected solar radiation and the thermal radiation emitted to space. Measurements of tropospheric CCN and IN over large areas have not been possible an

Quantification of left-to-right shunt through Patent Ductus Arteriosus by colour Doppler

Popular Abstract in Swedish Ductus arteriosus är ett kärl som finns hos foster för att styra blodet förbi lungorna. Kärlet stänger sig normalt inom 3 dagar efter födelsen men kan kvarstå öppet framför allt hos mycket för tidigt födda barn. Vid födelsen leder tryckförändringar i cirkulationen till att flödet i ductus vänder och blodet styrs istället till lungorna. Flödet genom ductus hos för tidigtThe aim of this thesis was to develop a non-invasive method to quantify the size of a shunt through a patent ductus arteriosus (PDA) by ultrasound and to test its usability in clinical settings. There is no consensus regarding the optimal management strategy for a PDA in premature infants. Non-steroidal anti-inflammatory drugs (NSAID) are the first treatment of choice. The use of NSAIDs, especiall

Complement factor I in health and disease.

Factor I (FI) is a crucial inhibitor controlling all complement pathways due to its ability to degrade activated complement proteins C3b and C4b in the presence of cofactors such as factor H, C4b-binding protein, complement receptor 1 or CD46. Complete deficiency of FI, which is synthesized mainly in the liver is rare and leads to complement consumption resulting in recurrent severe infections, gl

High-dose chemotherapy with autologous stem cell support in patients with metastatic non-seminomatous testicular cancer - a report from the Swedish Norwegian Testicular Cancer Group (SWENOTECA)

Background. The SWENOTECA IV protocol from 1995 is a prospective population-based study in metastatic non-seminomatous germ cell testicular cancer (NSGCT), designed for early identification of patients with poor response to standard cisplatin-based chemotherapy. A slow tumor marker decline (HCG T(1/2) > 3 days, AFP T(1/2) > 7 days) after BEP or BEP plus ifosfamide was regarded as poor response. Th

Measurement of charm and beauty jets in deep inelastic scattering at HERA

Measurements of cross sections for events with charm and beauty jets in deep inelastic scattering at HERA are presented. Events with jets of transverse energy E-T(jet) > 6 GeV and pseudorapidity - 1.0 < eta(jet) < 1.5 in the laboratory frame are selected in the kinematic region of photon virtuality Q(2) > 6 GeV2 and inelasticity variable 0.07 < y < 0.625. Measurements are also made requiring a jet

Path Dependence Research in Regional Economic Development: Cacophony or Knowledge Accumulation?

Henning M., Stam E. and Wenting R. Path dependence research in regional economic development: cacophony or knowledge accumulation, Regional Studies. The concept of path dependence has gained momentum in the social sciences, particularly in economic geography. This paper explores the empirical literature on path dependence and path creation in regional economic development. It offers a critical ref

From diets to foods: Using linear programming to formulate a nutritious, minimum-cost porridge mix for children aged 1 to 2 years

Background. Linear programming has been used extensively as a tool for nutritional recommendations. Extending the methodology to food formulation presents new challenges, since not all combinations of nutritious ingredients will produce an acceptable food. Furthermore, it would help in implementation and in ensuring the feasibility of the suggested recommendations. Objective. To extend the previou

Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study

Background: Our aim was to compare the effects of a Paleolithic ('Old Stone Age') diet and a diabetes diet as generally recommended on risk factors for cardiovascular disease in patients with type 2 diabetes not treated with insulin. Methods: In a randomized cross-over study, 13 patients with type 2 diabetes, 3 women and 10 men, were instructed to eat a Paleolithic diet based on lean meat, fish, f

Effects of Liming on Potential Oxalate Secretion and Iron Chelation of Beech Ectomycorrhizal Root Tips.

Liming is used to counteract forest decline induced by soil acidification. It consists of Ca and Mg input to forest soil and not only restores tree mineral nutrition but also modifies the availability of nutrients in soil. Ectomycorrhizal (ECM) fungi are involved in mineral nutrient uptake by trees and can recover them through dissolution of mineral surface. Oxalate and siderophore secretion are c

Experiences from the implementation of structured patient discharge information for safe medication reconciliation at a Swedish university hospital

Study objectives: A method for medication reconciliation that reduces medication errors and healthcare contacts when a patient is discharged from hospital, LIMM-DI (Lund integrated medicines management-discharge information) had been previously developed by the authors. LIMM-DI is structured information written for the patient and sent to the next caregiver. In this study, the use (implementation

Synchrotron X-ray diffraction studies of LiMn2O4 and Li4Mn5O12 structures at high pressure

Experimental study of the phase transition in the lithium-excess lithium-manganese spinel over the pressure range 0-13 GPa has shown its suppression. This observation implies that the Li/Mn ratio, associated with the manganese oxidation state, plays an important role in the high-pressure phase transformation of the lithium-manganese spinels. As indicated by the results, the occupation of the octah

Intentional suppression can lead to a reduction of memory strength: Behavioral and electrophysiological findings

Abstract in UndeterminedPrevious research has shown that the intentional suppression of unwanted memories can lead to forgetting in later memory tests. However, the mechanisms underlying this effect remain unclear. This study employed recognition memory testing and event-related potentials (ERPs) to investigate whether intentional suppression leads to the inhibition of memory representations at an

Broad-band multispectral microscope for imaging transmission spectroscopy employing an array of light-emitting diodes

Optical spectral analysis and multispectral imaging provide powerful means for characterizing samples in a wide variety of applications and on many spatial scales. We present a simple implementation of these techniques in the context of microscopy. A modified commercial microscope equipped with a CMOS imaging detector, combined with an array of light emitting diodes with emission ranging from ultr

Hemoglobin adducts as a measure of variations in exposure to acrylamide in food and comparison to questionnaire data

Measurement of haemoglobin (Hb) adducts from acrylamide (AA) and its metabolite glycidamide (GA) is a possibility to improve the exposure assessment in epidemiological studies of AA intake from food. This study aims to clarify the reliability of Hb-adduct measurement from individual single samples for exposure assessment of dietary AA intake. The intra-individual variations of AA- and GA-adduct le

Field-induced assembly of colloidal ellipsoids into well-defined microtubules.

Current theoretical attempts to understand the reversible formation of stable microtubules and virus shells are generally based on shape-specific building blocks or monomers, where the local curvature of the resulting structure is explicitly built-in via the monomer geometry. Here we demonstrate that even simple ellipsoidal colloids can reversibly self-assemble into regular tubular structures when

Sparse Chroma Estimation for Harmonic Audio

This work treats the estimation of the chromagram for harmonic audio signals using a block sparse reconstruction framework. Chroma has been used for decades as a key tool in audio analysis, and is typically formed using a Fourier-based framework that maps the fundamental frequency of a musical tone to its corresponding chroma. Such an approach often leads to problems with tone ambiguity, which we

The effect of temperature on the adiabatic laminar burning velocities of CH4-air and H-2-air flames

The effect of temperature on the adiabatic laminar burning velocities of CH4 + air and H-2 + air flames was analyzed. Available measurements were interpreted using correlation S-L = S-LO (T/T-o)(alpha). Particular attention was paid to the variation of the power exponent a with equivalence ratio at fixed ( atmospheric) pressure. Experimental data and proposed empirical expressions for a as a funct