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Background: Concurrent chemoradiotherapy is standard treatment for limited stage small-cell lung cancer (SCLC). Twice-daily thoracic radiotherapy of 45 Gy in 30 fractions is considered to be the most effective schedule. The aim of this study was to investigate whether high-dose, twice-daily thoracic radiotherapy of 60 Gy in 40 fractions improves survival. Methods: This open-label, randomised, phas

This perspective describes advances in determining membrane protein structures in lipid bilayers using small-angle neutron scattering (SANS). Differentially labeled detergents with a homogeneous scattering length density facilitate contrast matching of detergent micelles; this has previously been used successfully to obtain the structures of membrane proteins. However, detergent micelles do not mi

In vehicular communications systems the channel estimation filter suppresses the additive noise in channel estimates obtained from pilot symbols. Vehicular channels show local stationarity for a finite region in time and frequency, only. Such a process can be divided into consecutive stationarity regions, allowing to calculate a Wiener filter. We analyze the increase of the mean square error (MSE)

Writing over two decades ago, Stuart Hall (1991) first told the story of European identity as contradictory processes of marking symbolic boundaries and constructing symbolic frontiers between inside and outside, interior and exterior, belonging and otherness, which are central to any account of the political psychology of European integration. The study of European integration has come a long way

Two branches of gated ring oscillators (GRO) act as the delay lines in 2-dimension Vernier time-to-digital converter (TDC). The proposed architecture reduces dramatically the inherent latency of vernier structure. The already small quantization noise of the standard Vernier TDC is further first-order shaped by the GRO operation. The TDC has been simulated in 90nm CMOS technology. Operating from 50

Tungsten (W) and niobium (Nb) belong to the refractory metal group and are used as alloying elements in steels and superalloys for high demand products. These metals are also used in a high purity single-phase state for products within nuclear, space, military and research facilities.In the current study, tool wear development and surface quality at different cutting conditions have been evaluated

Recension av Poitr Wawrzeniuk, Med polska ögon: försvarsförmåga och hotbilder kring Östersjön i polsk militärrapportering 1919-1939

Wild bee populations are threatened by current agricultural practices in many parts of the world, which may put pollination services and crop yields at risk. Loss of pollination services can potentially be predicted by models that link bee abundances with landscape‐scale land‐use, but there is little knowledge on the degree to which these statistical models are transferable across time and space. Wild bee populations are threatened by current agricultural practices in many parts of the world, which may put pollination services and crop yields at risk. Loss of pollination services can potentially be predicted by models that link bee abundances with landscape-scale land-use, but there is little knowledge on the degree to which these statistical models are transferable across time and space.

Political theory of European union, through an engagement between political concepts and theoretical understandings, provides a means of identifying the EU as a political object. It is argued that understanding the projects, processes and products of European union, based on ‘sharing’ or ‘communion’, provides a better means of perceiving the EU as a political object rather than terms such as ‘inte

Drought and heat events, such as the 2018 European drought, interact with the exchange of energy between the land surface and the atmosphere, potentially affecting albedo, sensible and latent heat fluxes, as well as CO 2 exchange. Each of these quantities may aggravate or mitigate the drought, heat, their side effects on productivity, water scarcity and global warming. We used measurements of 56 e

The nature of the Neolithic Pitted Ware Culture (PWC) has been debated in Scandinavian archaeology since the beginning of the 20th century. This material culture post-dates the inception of an agro-pastoral Neolithic economy in the region (TRB) but demonstrate a semi-foraging lifeway. The PWC is considered elusive in the sense that the economy has been interpreted as either based on maritime forag

Alternating and parallel overlapping domain decomposition methods for the minimization of the total variation are presented. Their derivation is based on the predual formulation of the total variation minimization problem. In particular, the predual total variation minimization problem is decomposed into overlapping domains yielding subdomain problems in the respective dual space. Subsequently the

The minimization of a functional consisting of a combined L1/L2 data fidelity term and a total variation regularization term with a locally varying regularization parameter for the removal of mixed Gaussian–impulse noise is considered. Based on a related locally constrained optimization problem, algorithms for automatically selecting the spatially varying parameter are presented. Numerical experim