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ANIBAL, stable isotope-based quantitative proteomics by aniline and benzoic acid labeling of amino and carboxylic groups

Identification and relative quantification of hundreds to thousands of proteins within complex biological samples have become realistic with the emergence of stable isotope labeling in combination with high throughput mass spectrometry. However, all current chemical approaches target a single amino acid functionality (most often lysine or cysteine) despite the fact that addressing two or more amin

Patterns of somatic diagnoses in older people with intellectual disabilities : A Swedish 11-year register-based study of inpatient data

Aim: To investigate patterns of somatic inpatient ICD-10 diagnoses in people with intellectual disabilities (ID) 55 years and older in relation to age over an 11-year period, and to compare these patterns with a general population sample. Method: The study was based on Swedish national registers. The ID group (n=7936) comprised people who were aged 55 or above in 2012. They were age- and sexmatche

Defining authenticity in product design

Now, more than ever, we are told that ‘authenticity’ is an added value that customers want. The objective of this study is to determine what authenticity relevant for design is and whether it can be used as a standardised procedure to improve product design. In this study, industrial designers have been interviewed about their views on authenticity. This paper is a combined result of a literature Now, more than ever, we are told that 'authenticity' is an added value that customers want. The objective of this study is to determine what kind of authenticity is relevant to design, and whether it can be used as a standardised procedure to improve product design. In this study industrial designers were interviewed about their views on authenticity. The paper represents the combined result of a

Rapid short-term poly-beta-hydroxybutyrate production by Thiosphaera pantotropha in the presence of excess acetate

During substrate-limited growth, some strains of Thiosphaera pantotropha nitrify heterotrophically and denitrify aerobically. These processes are thought to be used as NADH overflow mechanisms, resulting from a restricted oxygen respiration capacity. In this study, the behavior of T. pantotropha regarding the NADH overflow in the presence of substantial concentrations of substrate was examined. Co

Feasibility study for the implementation of an automatic system for the detection of social interactions in the waiting area of automatic milking stations by using a video surveillance system

A well-planned waiting area is crucial for automatic milking systems. In an enclosed waiting area, cows of different rank compete for entering the milking station and they are exposed for a variety of social interactions. Such interactions could increase standing time and delay milking, which may result in stress, lameness, impaired welfare and reduced performance. The aim was to monitor the waiti

The long-run demand for money : a Wicksellian approach

The income velocity of money in several countries such as Sweden, the United States and Great Britain, displays a U-shaped pattern for the last one hundred years. This paper proposes an explanation of this secular behavior based on an extension of Wicksell’s work on velocity emphasizing the influence of institutional changes. The secular fall in velocity in the last half of the 19th century and th

A rapid method for analysis of fermentatively produced D-xylonate using ultra-high performance liquid chromatography and evaporative light scattering detection

An ultra-high performance liquid chromatogra-phy (UHPLC) based method for the analysis of D-xylonate was developed using an amide column in combination with an evaporative light scattering (ELS) detector. Separation of D-xylonate from other components of the fermentation medium was achieved. The dynamic range of the method was 0.2–7.0 g/L.

Resistivity inversion software comparison

The application of geophysics may assist in solving environmental, geotechnical and exploration problems. One commonly used method in such applications is electrical resistivity tomography (ERT). In order to interpret the results, inversion is needed to create models estimating distribution of resistivity in the ground. Several inversion programs are available for geophysicists to use. It is there

Direct Electron Transfer of Cellobiose Dehydrogenase on Positively Charged Polyethyleneimine Gold Nanoparticles

Efficient conjugation between biomolecules and electrode materials is one of the main challenges in the field of biosensors. Cellobiose dehydrogenase (CDH) is a monomeric enzyme, which consists of two separate domains: one catalytic dehydrogenase domain (DHCDH) carrying strongly bound flavin adenine dinucleotide (FAD) in the active site and a cytochrome domain (CYTCDH) carrying a b-type heme conne

Osmotic pressures of lysozyme solutions from gas-like to crystal states

We obtained osmotic pressure data of lysozyme solutions, describing their physical states over a wide concentration range, using osmotic stress for pressures between 0.05 bar and about 40 bar and volume fractions between 0.01 and 0.61. The osmotic pressure vs. volume fraction data consist of a dilute, gas-phase regime, a transition regime with a high-compressibility plateau, and a concentrated reg

Visible light-driven water oxidation with a subporphyrin sensitizer and a water oxidation catalyst

A new subporphyrin was synthesized for use as a molecular sensitizer in electrochemical and dye-sensitized photoelectrochemical water oxidation. A photoelectrochemical cell with a TiO2 electrode modified with the sensitizer and a molecular water oxidation catalyst generated higher photocurrent than reference cells that have electrodes modified with either the photosensitizer or the catalyst under

Inclusive and exclusive processes with a leading neutron in ep collisions

The inclusive and exclusive processes associated with a leading neutron in ep collisions at high energies are described using the color dipole formalism. We demonstrate that the available experimental HERA data on the xL (Feynman momentum) distribution of leading neutrons can be very well described taking into account the nonlinear (saturation) effects in the QCD dynamics. Moreover, we present our

A computer-assisted systematic quality monitoring method for cervical hip fracture radiography

BACKGROUND: A thorough quality analysis of radiologic performance is cumbersome. Instead, the prevalence of missed cervical hip fractures might be used as a quality indicator.PURPOSE: To validate a computer-based quality study of cervical hip fracture radiography.MATERIAL AND METHODS: True and false negative and positive hip trauma radiography during 6 years was assessed manually. Patients with tw