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Host modulation of excessive innate immune responses

A fundamental role of the innate immune system is to elicit a proper response against both invading pathogens and tissue damage or danger signals. Although the innate immune system often is successful in eliminating danger, an excessive host-response can result in severe tissue injury. Factors that contribute to the elimination of the microbe are the same factors that cause tissue injury. Therefor

Supporting Visual Editors using Reference Attributed Grammars

Reference attributed grammars (RAGs) extend Knuth’s attribute grammars with references. These references can be used to extend the abstract syntax tree to a graph. We investigate how RAGs can be used for implementing tools for visual languages. Programs in those languages can often be expressed as graphs.

New Galloylated Flavonoid Glycosides from Geranium stepporum DAVIS

Two new galloylated flavonoid glycosides, quercetin-3-O-(3 ''-O-galloyl)-beta-glucopyranoside (1) and quercetin-3-O-(3 ''-O-galloyl)-beta-galactopyranoside (2) were isolated from the aerial parts of Geranium stepporum along with the four known flavonoids, quercetin 3-O-beta-glucopyranoside (3), quercetin 3-O-beta-galactopyranoside (4), quercetin 3-O-(6 ''-O-galloyl)-beta-glucopyrinoside (5) and qu

Variations in graft and patient survival after kidney transplantation in Sweden: caveats in interpretation of center effects when benchmarking

P>Benchmarking and comparisons between transplantation centers are becoming more common. A crude comparison indicated a 50% difference in patient survival between centers in Sweden. A 'task group' was formed to refute or confirm and learn from this observation. Patient survival and graft survival of 5 933 patients transplanted at three different transplantation centers in Sweden (Stockholm, Gotebo

Effect of dietary alpha-ketoglutarate on blood lipid profile during hypercholesterolaemia in rats

Objective. The aim of the study was to determine the effect of -ketoglutarate on the blood lipid profile using a rat animal model with experimentally induced hypercholesterolaemia. Material and methods. The female and male (30/30) Wistar rats had ad libitum access to a diet containing cholesterol (1 %) and lard (10 %) throughout the entire experimental period (120 days). On day 60 of the study, bo

On decays of light unflavoured pseudoscalar mesons

The ongoing and planned experimental activities with direct reference to light unflavoured pseudoscalar mesons motivate a new theoretical study regarding their properties. An overview including details on new precise calculations is presented.

Soil erosion estimation based on rainfall disaggregation

Abstract in UndeterminedSoil loss estimation remains one of the most difficult research tasks all over the world. Current simulation tools are still not detailed enough to allow for realistic scenarios to handle soil erosion problems. A common problem is the lack of rainfall data at a sufficient level of detail. The present study uses a cascade disaggregation model to generate short time scale rai

Moderate hyperkalemia in hospitalized patients with cirrhotic ascites indicates a poor prognosis

Objective. Development of ascites in patients with liver cirrhosis is an ominous sign with a poor outcome. A liver transplantation must be considered, and it then becomes important to know if there are any factors indicating a worsened prognosis. Material and methods. We used official registers for a follow-up study of at least 5 years considering the prognosis of 155 prospectively recruited in-pa

Organizing disciplinary power in a knowledge organization

This article provides a systematic attempt to analyze the effects of performance appraisals, here conceptualized as tools for executing disciplinary power, and how the agency of employees is shaped. The article demonstrates how agency is enrolled by a broad set of disciplinary technologies aimed at behavior as well as the self, orchestrated in way that effectively short-circuits resistance. Drawin

Can a Chiral System Be Built on a Strongly Asymmetric Nucleon Configuration?

The multi-particle-plus-triaxial-rotor (MPR) model calculations were performed for several nuclei in the 100, 130 and 190 mass regions. It was found that chiral geometry can form even for very asymmetric nucleon configurations. However, the near-degeneracy of the partner bands may not be as good as the one observed for symmetric or slightly asymmetric configurations. DOI:10.5506/APhysPolB.44.341

Snake mitochondrial genomes: phylogenetic relationships and implications of extended taxon sampling for interpretations of mitogenomic evolution

Background: Snake mitochondrial genomes are of great interest in understanding mitogenomic evolution because of gene duplications and rearrangements and the fast evolutionary rate of their genes compared to other vertebrates. Mitochondrial gene sequences have also played an important role in attempts to resolve the contentious phylogenetic relationships of especially the early divergences among al

Competing water dissociation channels on rutile TiO2(110)

The interplay between two different water dissociation channels on rutile TiO2(110) was studied with the use of synchrotron radiation photoelectron spectroscopy. It was found that water dissociation at oxygen vacancies competes with water dissociation on defect-free regions such that one vacancy assisted dissociation event cancels one dissociation event on defect-free regions. The quenching affect

On the complexity of approximating the Hadwiger number

Unless P = NP there is no polynomial time approximation scheme (PTAS) for the problem of finding, for a graph G, the largest h such that the complete graph K-h is a minor of G. (C) 2008 Elsevier B.V. All rights reserved.

Prevalence of Tibiofemoral Osteoarthritis 15 Years After Nonoperative Treatment of Anterior Cruciate Ligament Injury: A Prospective Cohort Study.

BACKGROUND: The occurrence of osteoarthritis (OA), associated meniscal injuries, meniscectomy, and patient-related measures for patients treated nonoperatively after anterior cruciate ligament (ACL) injuries have not been well described in the literature in terms of natural history. HYPOTHESIS: Patients with ACL injury can achieve a low occurrence of tibiofemoral OA and good knee function when tre