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This study pools published data to describe the increase in glomerular filtration rate (GFR) from very premature neonates to young adults. The data comprises measured GFR (using polyfructose, Cr-51-EDTA, mannitol or iohexol) from eight studies (n=923) and involved very premature neonates (22 weeks postmenstrual age) to adulthood (31 years). A nonlinear mixed effects approach (NONMEM) was used to e

We present electrical characterization of broken gap GaSb-InAsSb nanowire heterojunctions. Esaki diode characteristics with maximum reverse current of 1750 kA/cm2 at 0.50 V, maximum peak current of 67 kA/cm2 at 0.11 V, and peak-to-valley ratio (PVR) of 2.1 are obtained at room temperature. The reverse current density is comparable to that of state-of-the-art tunnel diodes based on heavily doped p-

The 'Technological Innovation System' (TIS) framework and its system functions have become a popular analytical tool for the study of clean-tech innovation. There is increasing attention for the role of emerging economies in global clean-tech innovation, but the applicability of TIS to emerging economies cases is not entirely straightforward. A key issue is the limited geographical considerations,

The acute-phase protein C-reactive protein (CRP) recruits C1q to the surface of damaged cells and thereby initiates complement activation. However, CRP also recruits complement inhibitors, such as C4b-binding protein (C4bp) and factor H, which both block complement progression at the level of C3 and inhibits inflammation. To define how CRP modulates the classic complement pathway, we studied the i

We analyze the frequency and nature by which new firms are acquired by established businesses. Acquisitions are often considered to reflect a technology transfer process and to also constitute one way in which a "symbiosis" between new technology-based firms (NTBFs) and established businesses is realized. Using a micro-level dataset for Sweden in which we follow new entrants up to 18 years after e

Photoexcited states of a pyrazolate bridged PtPt dimer and a supramolecular RuCo complex with bipyridine-type ligands were studied using the pump-and-probe X-ray absorption spectroscopy method. The local structure refinement based on the fitting of XANES difference spectra has been performed. The theoretical analysis included the full multiple scattering calculations and the multidimensional inter

Background: Little is known about how parental gender equality early in their children lives can influence daughters’ decision to use contraceptive pills. Aim:The study aimed at exploring whether maternal working time and paternity leave in Sweden during the first two years of their daughters’ lives is associated with the use of oral contraceptives when they are adolescents or young adults. Materi

Abstract in German In diesem Kapitel beschäftigen wir uns mit vier Hindernissen, die einer produktiven Forschung über einen möglichen Einfluss der Sprache auf das Denken im Weg stehen. Zunächst ist da die Behauptung, es sei unmöglich, Sprache vom Denken zu trennen, die Frage des „Einflusses“ sei also nichtig. Als zweites gibt es das Argument, es sei unmöglich, Sprache von Kultur allgemein, insbesoIn this article, we discuss four obstacles that stand in the way for a productive investigation into the kind of influence that language may have on thinking. The first is that it is impossible to distinguish language from thought, so that the question of possible “influence” is mute. The second is that it is impossible to disentangle language from culture in general, and from social interaction i

According to the social defeat (SD) hypothesis, published in 2005, long-term exposure to the experience of SD may lead to sensitization of the mesolimbic dopamine (DA) system and thereby increase the risk for schizophrenia. The hypothesis posits that SD (ie, the negative experience of being excluded from the majority group) is the common denominator of 5 major schizophrenia risk factors: urban upb

Objectives To study the effect of insulin treatment in combination with metformin or an insulin secretagogue, repaglinide, on glycaemic regulation in non-obese patients with type 2 diabetes. Design Randomised, double blind, double dummy, parallel trial. Setting Secondary care in Denmark between 2003 and 2006. Participants Non-obese patients (BMI <= 27) with preserved beta cell function. Interventi

Short-term properties of atrial fibrillation (AF) frequency, f-wave morphology, and irregularity parameters have been thoroughly studied, but not long-term properties. In the present work, f-wave morphology is characterized by principal component analysis, introducing a novel temporal parameter defined by the cumulative normalized variance of the three largest principal components . Based on 7-day

The present paper shows the importance of the resolution of large unsteady flow structures in numerical simulations of cavitating flows. Three-dimensional simulations of the flow through a throttle geometry representative for fuel injectors have been performed to characterise the inception and development of cavitation, adopting the implicit Large Eddy Simulation approach. The two-phase flow has b

The gas-phase decompositions of a thiazole-substituted dioxetanone, in both the natural and anionic forms, were investigated theoretically in a CASSCF/CASPT2 study. The neutral conjugated thiazole (with or without a hydroxyl group) substitution on the dioxetanone has no evident effect on the dissociation; however, a subsequent deprotonation - invoking charge-transfer excitations from the thiazole

It is generally acknowledged that wetlands and barrier islands can reduce surge and waves. However, while a general qualitative understanding of these interactions is available in the scientific literature, quantification of these interactions is lacking and has previously been based on limited data of relatively poor quality. The overall aim of this study was to improve the understanding of the i

The presence of different time scales in a dynamic model significantly hampers the efficiency of its simulation. In multibody systems the fact is particularly relevant, as the mentioned time scales may be very different, due for example to the coexistence of mechanical components controlled by electronic drive units, and may also appear in conjunction with significant nonlinearities. This paper pr

Deficiencies of complement proteins of the classical pathway are strongly associated with the development of autoimmune diseases. Deficiency of Clr has been observed to occur concomitantly with deficiency in Cls and 9 out of 15 reported cases presented systemic lupus erythernatosus (SLE). Here, we describe a family in which all four children are deficient in Cls but only two of them developed SLE.