Sökresultat

Ett alternativ för att studera immunceller i cellkulturer utan djurprodukter Cancer är ett samlingsnamn för en rad olika sjukdomar som kan uppstå var som helst i människokroppen. Tillståndet kännetecknas av att tumörer bildas i en viss kroppsdel som kan spridas till andra delar. Tumörer är komplexa strukturer som inte bara innehåller cancerceller. Cancercellerna i en tumör omringas av en så-kallaThe use of cancer cell cultures, including immune cells, is essential in cancer research for developing immunotherapies in pre-clinical investigations. However, so far, a large number of animal-derived products are utilised in cell culturing, where experimental variations and reproducibility problems have been reported. Most studies have also only investigated the differentiation of monocytes into

Developing a new tool for the study of human brain development “If the human brain were so simple that we could understand it, we would be so simple that we couldn’t” physicist Emerson Pugh once said. Nevertheless, despite its complexity, researchers are trying to figure out one of the human body's most vital organs. Understanding the development of the brain is crucial to understanding how i

It is difficult to definitively say who the greatest Formula One driver is. It is a subjective assessment and can depend on a variety of factors, including the driver’s skill, their results and accomplishments, their team and car, and the era in which they competed. Some of the most successful and highly regarded Formula One drivers include Michael Schumacher, Ayrton Senna, Lewis Hamilton, Alain P

Zooarchaeological studies have played a crucial role in understanding the pre-historic societies of Scania. The analysis of animal remains from archaeological sites has provided insights into the subsistence strategies, economic practices, and cultural beliefs of the people who lived in the region. Remains from horse, dog, wild boar, and man are commonly observed in offering and burial contexts. D

De antroprogena kemikalierna PFAS, som står för poly- och perfluorerade alkylsubstanser, är nästan omöjliga att bryta ned och har en förmåga att ansamlas i oss människor och andra organismer. De är även kopplade till en rad olika hälsoproblem som olika former av cancer, hormonell obalans och fertilitetsproblem. Samtidigt är dessa kemikalier vitt använt i olika industriella samt vardagliga produkteAqueuous Film Forming Foam (AFFF) containing Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) is one of the major sources of groundwater contamination in Sweden. Groundwater contamination caused by the use of AFFF in correlation to fire training events was investigated in Kallinge, Sweden. At the site groundwater was previously used as a drinking water source consequently affecting the inhabit

When a fuel cell stack is assembled it is compressed to ensure gas tightness, and as a consequence, the Gas Diffusion Layer (GDL) will intrude into the channels of the Bipolar Plate (BPP). In this work, the GDL is studied in compression tests and through intrusion measurements. Based on the collected data from the measurements, an approximative method is developed to calculate the intruded profile

Att social isolering och ofrivillig ensamhet har negativa effekter på den psykiska och fysiska hälsan är ingen nyhet. Ensamhet är en folksjukdom. Och undersökningar visar att den ofrivilliga ensamheten har starka kopplingar till boendet och det egna hemmet. Tiden under Covid-19-pandemin har präglats hårt av uppmaningen om ”social distansiering”. Ännu mer tid har spenderats i eller i närheten av h

When installing new research equipment at the synchrotron research laboratory MAX IV, a final positional accuracy of tens of microns is usually needed. To obtain that accuracy, initial reference points must be placed within 2 mm from the nominal target points in CAD, in a process referred to as bluelining. It is currently a manual process where points from a virtual environment are transferred to

Ungefär en tredjedel av Sveriges befolkning är friluftsaktiva i skog- och mark minst en gång i veckan. Detta intresse ökar för varje år, och under Covid-19-pandemin nådde andelen friluftsintresserade nya höjder där femtio procent av Sveriges totala befolkning aktivt deltog i utomhusaktiviteter. Men, även fast intresse för utemiljöer och naturupplevelser finns, har alla inte samma möjlighet att ta About a third of Sweden's population is active outdoors in forests and fields at least once a week. This interest increases every year, and during the Covid-19 pandemic the percentage of people interested in the outdoors reached new heights where fifty percent of Sweden's total population actively participated in outdoor activities. But, even if there is a strong interest in outdoor enviro

In this Master’s thesis, we describe two recent methods aimed at constructing complex-valued harmonic morphisms and p-harmonic functions on Riemannian manifolds. The main tools for these constructions are the common eigenfunctions of the classical Laplace-Beltrami operator τ and the recently introduced conformality operator κ. We then apply the above methods for constructing solutions on the compa

Omkring 10% av Sveriges befolkning lider av kronisk njursjukdom. För de flesta patienter med långt gången, så kallad terminal njursjukdom är njurtransplantation den bästa behandlingen, både för patientens livskvalitet och ur ett hälsoekonomiskt perspektiv. Många patienter som har en villig donator passar inte med denna på grund av icke kompatibla blodgrupper eller för att de har antikroppar motBackground: For most patients with end stage renal disease (ESRD) kidney transplantation is the best treatment option. Best outcomes are achieved with living donation. To increase access to living donation for patients who are not compatible with their living donors, Kidney Exchange Programs (KEPs) have evolved. By exchanging donors, compatibility can be achieved thus enabling transplantation.

Telomeres, the guardians of the chromosomes Telomeres are structures found at the end of eukaryotic chromosomes. They are composed of a repetitive DNA sequence and proteins, and their main function is to protect the chromosome ends. In human somatic cells telomeres shorten with each cell division, acting as a biological clock of cell aging. However, cancer cells are able to divide infinitely by r

Vitesklausulen är ett vanligt förekommande avtalsvillkor, särskilt mellan kommersiella parter. Det är inte heller ovanligt att dessa vitesklausuler författas på det engelska språket. Anledningen (eller anledningarna) till varför avtalsparterna väljer engelska som avtalsspråk varierar, och bero-ende på anledningarna varierar också domstolens bedömning av vitesklau-sulen då svensk lag utgör avtalsstClauses stipulating an agreed sum payable upon breach of contract are a common feature in contracts, especially in commercial contracts. For dif-ferent reason(s), such clauses are often written in English. The reason(s) for writing a contract in English may vary but affect how the clause is con-strued under Swedish law. The thesis uses both the legal dogmatic method and the comparative method, whe

Syftet med detta examensarbete är att vidareutveckla en analysmodell inom deformationslokalisering för att få en bredare kunskap om det mekaniska beteendet hos ett geomaterial. Undersökning av lokala egenskaper hos ett jordprov kräver en fullfältsmätnin-gsteknik som i detta arbete är ultraljudstomografi. Anvädning av ultraljudtomografi inom ramarna av geomekanik har med tiden påvisat goda result

Vid sidan av strävan att uppnå AI-modeller som kan skapa extremt verklighetstrogna texter och bilder existerar även målet att kunna generera mänskligt tal. Målet med detta område, kallat "talsyntes", är att skapa en syntetisk mänsklig röst som har förmågan att läsa upp en given text. Detta kan t.ex. användas i automatiserad kundtjänst eller för personliga assistenter. Själva problemet haThe emergence of machine learning based text-to-speech systems have made fully automated customer service voice calls, spoken personal assistants, and the creation of synthetic voices seem well within reach. However, there are still many technical challenges with creating such a system which can generate audio quickly and of high enough quality. One critical component of the typical text-to-speech

Currently, there are no given directives and regulations on how hydrogen refueling stations should be designed in Sweden. A proposal regarding hydrogen refueling stations H2-TSA, is being developed by Energigas Sverige and is expected to be published in 2023. The aim of this thesis is to contribute to development and future revisions of H2-TSA. It is done by analyze how a general hydrogen refuelin

The focus of this thesis is the myths and ideologies inscribed into the aesthetics, narratives and gameplay of post-apocalyptic videogames. The aim is to discuss how the conditions and conventions of the game medium shape what is presented to us as a modern, secular form of apocalypticism. The case studies presented are the two well-known videogames Fallout 4 and The Last Of Us. The research focus

Arabinoxylan (AX) is a beneficial dietary fibre found in cereals such as oats. This crop also possesses high quality proteins and other fibres like b-glucan that help reduce LDL and postprandial blood glucose levels. Lines with a higher content of AX have been recently identified, and the current study aimed to investigate the structure of the AX fibre in these lines in comparison to the commercia

This thesis aims to study how the legitimacy of the EU’s pandemic crisis response in connection to green policies, in the interinstitutional exchange, is supported or undermined by connected frames and a subordinate master frame over the course of the first six months of the unfolding pandemic. Six EU institutions’ residents, who “have a say” on economic crisis measures, were picked from the Europ

Bakgrund: Majoriteten av personer med schizofreni upplever begränsningar relaterat till aktivitet och delaktighet i vardagliga aktiviteter. Symtombilden består till stor del av positiva och negativa symtom och en bristande sjukdomsinsikt. Det råder begränsad evidens kring hur arbetsterapeutiska interventioner påverkar aktivitet och delaktighet för personer med schizofreni. Syfte: Att kartlägga arbBackground: Most people with schizophrenia experience limitations related to activity and participation in everyday activities. The symptoms largely consist of positive and negative symptoms and a lack of disease insight. There is limited evidence on how occupational therapy interventions affect people with schizophrenia. Aim: To map occupational therapy interventions that affect activity and part