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Antitumor effect of radioactive cisplatin (191Pt) on nude mice

PURPOSE: To investigate the effect of (191)Pt-cisplatin in vivo in terms of the antitumor effect and general toxicity on tumor-bearing nude mice. METHODS AND MATERIALS: Tumor-bearing (human squamous cell carcinoma, AB) nude mice were divided into four groups and given, i.p., physiological saline (controls), cisplatin, (191)Pt-cisplatin (80 MBq/mg), or (191)Pt-cisplatin (160 MBq/mg), respectively.

Fluorescence lidar imaging of fungal growth on high-voltage outdoor composite insulators

Remote fluorescence imaging of fungal growth on polymeric high-voltage insulators was performed using a mobile lidar system with a laser wavelength of 355 nm. Insulator areas contaminated by fungal growth could be distinguished from clean surfaces and readily be imaged. The experiments were supported by detailed spectral studies performed in laboratory using a fibre-optic fluorosensor incorporatin

Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps

Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide. Pneumococci can counteract the action of neutrophils with an antiphagocytic capsule and through electrochemical repulsion of antimicrobial peptides via addition of positive charge to the surface. Pneumococci are captured, but not killed in neutrophil extracellular traps (NETs). Here, we study the role of the polysaccha

Anticipation requires adaptation

To successfully interact with a dynamic world, our actions must be guided by a continuously changing anticipated future. Such anticipations must be tuned to the processing delays in the nervous system as well as to the slowness of the body, something that requires constant adaptation of the predictive mechanisms, which in turn require that sensory information be processed at different time-scales.

Influence of packaging material and storage condition on the sensory quality of broccoli

The sensory quality of broccoli stored in modified atmosphere packages was studied. Oriented polypropylene (OPP), polyvinyl chloride (PVC) and low-density polyethylene (LDPE) were used as packaging materials. The LDPE contained an ethylene-absorbing sachet. The samples were stored for I week, either at a constant temperature of 10 degreesC or for 3 days at 4 degreesC, followed by 4 days at 10 degr

Density functional theory for polymer fluids with molecular weight polydispersity

We develop a density-functional theory for polydisperse polymer fluids satisfying the Schulz-Flory distribution. The resulting equations are remarkably simple and quickly solved, the computational effort scaling with the polydispersity index, rather than the average molecular weight. Equilibrium, or "living", polymers enter naturally as very polydisperse samples. We illustrate the importance of po

Identification of mecA-related oxacillin resistance in staphylococci by the E test and the broth microdilution method

A set of 165 strains of different staphylococcal species, 67 Staphylococcus aureus, 71 novobiocin-sensitive coagulase-negative staphylococci (CNS) and 27 novobiocin-resistant CNS was used. The oxacillin and methicillin MICs were recorded after 24 and 42 h of incubation at 35 degrees C and at 30 degrees C. Significantly higher MICs were recorded at 30 degrees C compared with 35 degrees C. While a p

The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice

The nonobese diabetic ( NOD) Nss1 and Idd5 loci have been associated with sialadenitis development in mice. In this study the NOD Nss1 and Idd5 loci were backcrossed onto the healthy control strain B10. Q by using the speed congenic breeding strategy, resulting in three congenic strains: B10. Q. Nss1, B10. Q. Nss1/Idd5 heterozygous and B10. Q. Nss1/Idd5 homozygous. We investigated the effects of t

Diffusion of glucose and insulin in a swelling N-isopropylacrylamide gel

The diffusional characteristics for poly(N-isopropylacrylamide) (NiPAAm) gel have been investigated. This gel is a critical gel which means that small changes in the environment influence the gel volume considerably. The effective diffusion coefficients for the solutes glucose and insulin were determined in batch experiments with the solutes diffusing out from small cylindrical gel bodies with dia

A prospective multicentre study in Sweden and Norway of mental distress and psychiatric morbidity in head and neck cancer patients

A Swedish/Norwegian head and neck cancer study was designed to assess prospectively the levels of mental distress and psychiatric morbidity in a heterogeneous sample of newly diagnosed head and neck cancer patients. A total of 357 patients were included. The mean age was 63 years, and 72% were males. The patients were asked to answer the HAD scale (the Hospital Anxiety and Depression scale) six ti

Determination of hyperfine-induced transition rates from observations of a planetary nebula

Observations of the planetary nebula NGC3918 made with the STIS instrument on the Hubble Space Telescope reveal the first unambiguous detection of a hyperfine-induced transition 2s2p P-3(0)o-->2s(2) S-1(0) in the berylliumlike emission line spectrum of N IV at 1487.89 Angstrom. A nebular model allows us to confirm a transition rate of 4x10(-4) sec(-1)+/-33% for this line. The measurement represent

Gas sensing by tunable multimode diode laser using correlation spectroscopy

A novel method to use multimode diode lasers for gas detection is demonstrated. The relationship between the intensity decay of partially absorbed multiple modes and the target gas concentration is presented. The gas concentration is retrieved by a linear-regression-based procedure applied on simultaneously recorded absorption signals in a dual-beam wavelength-modulation configuration. Signals of

Extended term analysis of Mo II

The spectrum of singly ionized molybdenum has been recorded with Fourier transform spectrometers in the wavelength interval 1500-7000 Angstrom. We report improved energy values for a total of 330 levels, 153 even and 177 odd, which belong to the 4d(5), 4d(4)5s, 4d(3)5s(2), 4d(4)6s, 4d(4)5d, 4d(4)5p and 4d(3)5s5p configurations. 110 of the levels have been found in the present analysis. We have als

Pax3-fkhr and pax7-fkhr fusion genes impact outcome of alveolar rhabdomyosarcoma in children

Rhabdomyosarcoma is a highly malignant embryonic tumor of childhood. Two specific translocations t(2;13)(q35;q14) and t(1;13)(p36;q14) have been identified in about 75-80% of ARMS cells. The aim of this multicenter study was to analyze the relationships between the identified fusion transcripts and survival including some selected clinical parameters. The extent of disease was graded according to