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Treatment with Antithrombotics in the Last Year of Life—Incidence of Bleeding and Side Effects After Deprescribing

Background: Patients in palliative care are often treated with antithrombotics, even in the late stages of disease. Clear guidelines regarding deprescribing are lacking. Objective: The aims of this study were to investigate bleeding as a side effect of antithrombotic treatments the last year in life and map the timing of deprescribing. Methods: A retrospective cohort study was performed. All medic

Gambling Habits and Attitudes among Athlete and Non-Athlete High School Students in Skåne Region, Sweden

Previous literature has reported increased rates of gambling problems in athletes compared to non-athletes. More liberal gambling-related attitudes have been suggested as a reason, although this rarely has been researched. The present study aimed to examine gambling experience, gambling problems, and gambling-related attitudes and parental gambling experience in high school students, comparing stu

Intratumoral Distribution of [177Lu]Lu-PSMA-617 Over Time and in Relation to Diagnostic Tracers in Animal Models of Prostate Cancer

Introduction: Prostate-specific membrane antigen (PSMA) is a target for diagnostic positron emission tomography (PET)-tracers and radiopharmaceutical therapy (RPT), for example, [177Lu]Lu-PSMA-617, in prostate cancer. This autoradiography study investigates [177Lu]Lu-PSMA-617 intratumoral distribution over time, compared with PSMA expression, proliferation (Ki67), and [68Ga]Ga-PSMA-11, [18F]F-PSMA

Managing the Past and the Future : Evolving Professional Roles of Archivists in Contemporary Sweden

This paper focuses on contemporary archival professionals in Sweden. The research questions posed are: RQ1: What are the different facets of archival work commonly described in employment advertisements directed at archival professionals? RQ2: What are the desirable personal traits that employers seek when hiring an archival professional? The material consists of job advertisements from the year 2

Non-invasive pressure-volume loops show high arterial elastance in children with repaired tetralogy of Fallot

BACKGROUND: Children with repaired tetralogy of Fallot (rToF) often have pulmonary regurgitation with right ventricular (RV) dilatation and dysfunction, whereas less is known about the effect on the left ventricle (LV). The aim was to investigate LV haemodynamic variables derived from non-invasive pressure-volume loops in children with rToF and how they compare to controls and previous research on

Total adiponectin in indigenous Melanesians on Kitava

Objectives: Experimental and small human studies have indicated that high total adiponectin levels have beneficial cardiometabolic effects. In contrast, however, high total adiponectin levels are also associated with higher all-cause and cardiovascular mortality in thoroughly adjusted epidemiological studies. To gain further insight into these seemingly contradictory results, we report results on

Consistency between the ACGIH TLV for hand activity and proposed action levels for wrist velocity and forearm muscular load based on objective measurements : an example from the assembly industry

Objectives. This study aimed to investigate the consistency between results of the American Conference for Governmental Occupational Hygienists (ACGIH) threshold limit value (TLV) for hand activity and proposed action levels of objective measurements in risk assessments of work-related musculoskeletal disorders. Methods. Wrist velocities and forearm muscular load were measured for 11 assemblers du

Partial Clinical Remission of Type 1 Diabetes in Swedish Children : A Longitudinal Study from the Swedish National Quality Register (SWEDIABKIDS) and the Better Diabetes Diagnosis (BDD) Study

Aims/Hypotheses: To investigate the frequency and characteristics of partial remission in Swedish children with type 1 diabetes and whether the insulin delivery method, that is, continuous subcutaneous insulin infusion (CSII) or multiple daily injections (MDIs), affects incidence and duration of this period, 2007-2011. Factors that increase the proportion of subjects who enter partial remission an

Revised criteria for diagnosis and staging of Alzheimer's disease : Alzheimer's Association Workgroup

The National Institute on Aging and the Alzheimer's Association convened three separate work groups in 2011 and single work groups in 2012 and 2018 to create recommendations for the diagnosis and characterization of Alzheimer's disease (AD). The present document updates the 2018 research framework in response to several recent developments. Defining diseases biologically, rather than based on synd

LES of pilot n-heptane ignition and its interaction with the lean premixed methane–air mixture in a dual-fuel combustion engine

Large eddy simulations of pilot fuel ignited, lean premixed, natural gas engines are performed to study the pilot-ignition process and its subsequent interaction with the premixed charge. The injection pressure (Pinj) and injection duration (Δinj) are varied (i.e. 800 bar/760μs, 800 bar/500μs, and 400bar/760μs) to study the impact of the injection process on the subsequent combustion evolution. Op

Realizing Room-Temperature Ferromagnetism in Molecular-Intercalated Antiferromagnet VOCl

2D van der Waals (vdW) magnets are gaining attention in fundamental physics and advanced spintronics, due to their unique dimension-dependent magnetism and potential for ultra-compact integration. However, achieving intrinsic ferromagnetism with high Curie temperature (TC) remains a technical challenge, including preparation and stability issues. Herein, an applicable electrochemical intercalation

Excess Mortality and Loss of Life Expectancy After Myocardial Infarction : A Registry-Based Matched Cohort Study

BACKGROUND: The effect of myocardial infarction (MI) on life expectancy is difficult to study because the prevalence of MI hinders direct comparison with the life expectancy of the general population. We sought to assess this in relation to age, sex, and left ventricular ejection fraction (LVEF) by comparing individuals with MI with matched comparators without previous MI. METHODS: We included pat

Optimal Seeding in Large-Scale Super-Modular Network Games

We study optimal seeding problems for binary super-modular network games. The system planner's objective is to design a minimal cost seeding guaranteeing that at least a predefined fraction of the players adopt a certain action in every Nash equilibrium. Since the problem is known to be NP-hard and its exact solution would require full knowledge of the network structure, we focus on approximate so

Agnes Smedley and the Indian anarchists in Weimar Berlin

This article examines the entangled worlds of anti-colonialism and anarchism in Weimar era Berlin. Looking particularly at Agnes Smedley and her partner in Berlin, Virendranath Chattopadhyaya, as well as M.P.T.Acharya and others, the article explores the ways in which these figures approached the question of anarchism in relation to Indian anti-colonialism. While recent scholarship has focused on

Cohort study of prediction of venous thromboembolism in emergency department patients with extremity symptoms

Despite diagnostic algorithms, identification of venous thromboembolism (VTE) in emergency departments (ED) remains a challenge. We evaluated symptoms, background, and laboratory data in 27,647 ED patients presenting with pain, swelling, or other symptoms from the extremities, and identified predictors of VTE diagnosis within one year. Predictors of a clinical decision to perform phlebography, ult

The welfare state

The first keyword, Welfare State, sets out to problematise the term itself. The welfare state is a national construct, a ‘national social state’ as Etienne Balibar calls it. Thus, transnational or global migration is often construed as a disruptive force, potentially destabilising the welfare state and the nation. This keyword entry critically examines common conceptions of what the welfare state